EP0863770A4 - Milieu de contraste et son utilisation - Google Patents

Milieu de contraste et son utilisation

Info

Publication number
EP0863770A4
EP0863770A4 EP96916620A EP96916620A EP0863770A4 EP 0863770 A4 EP0863770 A4 EP 0863770A4 EP 96916620 A EP96916620 A EP 96916620A EP 96916620 A EP96916620 A EP 96916620A EP 0863770 A4 EP0863770 A4 EP 0863770A4
Authority
EP
European Patent Office
Prior art keywords
contrast medium
contrast
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96916620A
Other languages
German (de)
English (en)
Other versions
EP0863770A1 (fr
Inventor
Rafi Korenstein
Avi Dascalu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Israel Humanitarian Foundation Ltd
Original Assignee
Israel Humanitarian Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Israel Humanitarian Foundation Ltd filed Critical Israel Humanitarian Foundation Ltd
Publication of EP0863770A1 publication Critical patent/EP0863770A1/fr
Publication of EP0863770A4 publication Critical patent/EP0863770A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP96916620A 1995-05-31 1996-05-24 Milieu de contraste et son utilisation Withdrawn EP0863770A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL11392695 1995-05-31
IL11392695A IL113926A (en) 1995-05-31 1995-05-31 Contrast medium with improved patient's tolerance thereto and its use
PCT/US1996/007666 WO1996038183A1 (fr) 1995-05-31 1996-05-24 Milieu de contraste et son utilisation

Publications (2)

Publication Number Publication Date
EP0863770A1 EP0863770A1 (fr) 1998-09-16
EP0863770A4 true EP0863770A4 (fr) 2001-01-10

Family

ID=11067540

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96916620A Withdrawn EP0863770A4 (fr) 1995-05-31 1996-05-24 Milieu de contraste et son utilisation

Country Status (5)

Country Link
EP (1) EP0863770A4 (fr)
AU (1) AU707118B2 (fr)
CA (1) CA2222429A1 (fr)
IL (1) IL113926A (fr)
WO (1) WO1996038183A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2191118A (en) * 1937-06-03 1940-02-20 Firm Of N V Orgachemia Pyelographic preparation
US2870063A (en) * 1955-07-05 1959-01-20 Mallinckrodt Chemical Works X-ray contrast composition comprising substantially amylose-free amylopectin in aqueous solution of contrast agent
US3984571A (en) * 1970-03-10 1976-10-05 E. R. Squibb & Sons, Inc. Hydrocolloid containing liquid carrier for a diagnostic or therapeutic agent
EP0354836A1 (fr) * 1988-08-10 1990-02-14 Guerbet S.A. Polymères iodés à squelette dextrane, leurs procédés de préparation et leurs applications comme produits de contraste
US5019370A (en) * 1989-07-10 1991-05-28 University Of Kentucky Research Foundation Biodegradable, low biological toxicity radiographic contrast medium and method of x-ray imaging
WO1995010306A1 (fr) * 1993-10-15 1995-04-20 Alliance Pharmaceutical Corp. Prophylaxie relative a l'administration par voie parenterale de dispersions particulaires
WO1996035429A1 (fr) * 1995-05-10 1996-11-14 Schering Aktiengesellschaft Utilisation d'agents anti-inflammatoires non steroidiens pour ameliorer la compatibilite physiologique de preparations pharmaceutiques particulaires

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE34077E (en) * 1988-05-02 1992-09-22 Cryomedical Sciences, Inc. Blood substitute
US5199951A (en) * 1990-05-17 1993-04-06 Wayne State University Method of drug application in a transporting medium to an arterial wall injured during angioplasty
US5334370A (en) * 1993-02-04 1994-08-02 Sterling Winthrop Inc. Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2191118A (en) * 1937-06-03 1940-02-20 Firm Of N V Orgachemia Pyelographic preparation
US2870063A (en) * 1955-07-05 1959-01-20 Mallinckrodt Chemical Works X-ray contrast composition comprising substantially amylose-free amylopectin in aqueous solution of contrast agent
US3984571A (en) * 1970-03-10 1976-10-05 E. R. Squibb & Sons, Inc. Hydrocolloid containing liquid carrier for a diagnostic or therapeutic agent
EP0354836A1 (fr) * 1988-08-10 1990-02-14 Guerbet S.A. Polymères iodés à squelette dextrane, leurs procédés de préparation et leurs applications comme produits de contraste
US5019370A (en) * 1989-07-10 1991-05-28 University Of Kentucky Research Foundation Biodegradable, low biological toxicity radiographic contrast medium and method of x-ray imaging
WO1995010306A1 (fr) * 1993-10-15 1995-04-20 Alliance Pharmaceutical Corp. Prophylaxie relative a l'administration par voie parenterale de dispersions particulaires
WO1996035429A1 (fr) * 1995-05-10 1996-11-14 Schering Aktiengesellschaft Utilisation d'agents anti-inflammatoires non steroidiens pour ameliorer la compatibilite physiologique de preparations pharmaceutiques particulaires

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
ADAMS MD ET AL: "A rat EEG model for evaluating contrast media neurotoxicity.", INVESTIGATIVE RADIOLOGY, SEP 1988, VOL. 23 SUPPL 1, PAGE(S) S217-S219, XP000929806 *
AGMON YORAM ET AL: "Nitric oxide and prostanoids protect the renal outer medulla from radiocontrast toxicity in the rat.", JOURNAL OF CLINICAL INVESTIGATION, vol. 94, no. 3, 1994, pages 1069 - 1075, XP000892176, ISSN: 0021-9738 *
AINSWORTH J ET AL: "The arteriographic appearances following the use of intra-arterial vasodilator agents in occlusive arterial disease.", CLINICAL RADIOLOGY, OCT 1967, VOL. 18, NO. 4, PAGE(S) 439-44, XP000929786 *
CANTLEY LLOYD G ET AL: "Role of endothelin and prostaglandins in radiocontrast-induced renal artery constriction.", KIDNEY INTERNATIONAL 1993, vol. 44, no. 6, 1993, pages 1217 - 1223, XP000892177, ISSN: 0085-2538 *
CLAYTON D.G. ET AL: "Cardiovascular response during cerebral angiography under general and local anaesthesia", ANAESTHESIA, 1989, VOL. 44, NO. 7, PAGE(S) 599-602, XP000929807 *
DOUST, BRUCE D. ET AL: "Effects of dextran infusion, glucose infusion, and state of hydration on cerebral toxicity of arteriographic contrast media", RADIOLOGY, 1972, VOL. 103, NO. 3, PAGE(S) 607-9, XP000929792 *
FEINBERG S J ET AL: "HEMODYNAMIC FUNCTION IN DOGS WITH CHRONIC OBSTRUCTIVE JAUNDICE EFFECTS OF RADIOCONTRAST MEDIUM", JOURNAL OF SURGICAL RESEARCH 1990, vol. 49, no. 1, 1990, pages 55 - 61, XP000892197, ISSN: 0022-4804 *
HOEM NO ET AL: "Effects of intravenous radiographic contrast media on the blood pressure and on factors of the contact activation system in the rat.", ACTA PHARMACOLOGICA ET TOXICOLOGICA, SEP 1986, VOL. 59, NO. 3, PAGE(S) 189-94, XP000929789 *
MURPHY D.J.: "Cerebrovascular permeability after meglumine iothalamate administration", NEUROLOGY, 1973, VOL. 23, NO. 9, PAGE(S) 926-936, XP000929853 *
SCHMIT DB ET AL: "Safe ex vivo coronary angiography with isosmotic contrast agent.", JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, AUG 1996, VOL. 112, NO. 2, PAGE(S) 306-9, XP000929773 *
See also references of WO9638183A1 *

Also Published As

Publication number Publication date
CA2222429A1 (fr) 1996-12-05
EP0863770A1 (fr) 1998-09-16
WO1996038183A1 (fr) 1996-12-05
IL113926A (en) 2000-06-01
IL113926A0 (en) 1995-08-31
AU707118B2 (en) 1999-07-01
AU5930996A (en) 1996-12-18

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