EP0861322A4 - Antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for replication - Google Patents

Antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for replication

Info

Publication number
EP0861322A4
EP0861322A4 EP95937415A EP95937415A EP0861322A4 EP 0861322 A4 EP0861322 A4 EP 0861322A4 EP 95937415 A EP95937415 A EP 95937415A EP 95937415 A EP95937415 A EP 95937415A EP 0861322 A4 EP0861322 A4 EP 0861322A4
Authority
EP
European Patent Office
Prior art keywords
replication
host cell
antiviral compounds
inhibit interaction
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95937415A
Other languages
German (de)
French (fr)
Other versions
EP0861322A1 (en
Inventor
Peter Palese
Robert O'neill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mount Sinai Medical Center
Original Assignee
Mount Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mount Sinai Medical Center filed Critical Mount Sinai Medical Center
Publication of EP0861322A1 publication Critical patent/EP0861322A1/en
Publication of EP0861322A4 publication Critical patent/EP0861322A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
EP95937415A 1995-10-06 1995-10-06 Antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for replication Withdrawn EP0861322A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/013044 WO1997012967A1 (en) 1995-10-06 1995-10-06 Antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for replication

Publications (2)

Publication Number Publication Date
EP0861322A1 EP0861322A1 (en) 1998-09-02
EP0861322A4 true EP0861322A4 (en) 2002-06-26

Family

ID=22249941

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95937415A Withdrawn EP0861322A4 (en) 1995-10-06 1995-10-06 Antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for replication

Country Status (4)

Country Link
EP (1) EP0861322A4 (en)
JP (1) JPH11513252A (en)
AU (1) AU3953895A (en)
WO (1) WO1997012967A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750394A (en) 1994-05-20 1998-05-12 The Mount Sinai Medical Center Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication
US6503703B1 (en) 1995-05-19 2003-01-07 Mount Sinai School Of Medicine Of New York University Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010632A1 (en) * 1993-10-12 1995-04-20 Emory University Anti-paramyxovirus screening method and vaccine
WO1995032310A1 (en) * 1994-05-20 1995-11-30 The Mount Sinai Medical Center Identification and use of antiviral compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010632A1 (en) * 1993-10-12 1995-04-20 Emory University Anti-paramyxovirus screening method and vaccine
WO1995032310A1 (en) * 1994-05-20 1995-11-30 The Mount Sinai Medical Center Identification and use of antiviral compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9712967A1 *

Also Published As

Publication number Publication date
EP0861322A1 (en) 1998-09-02
WO1997012967A1 (en) 1997-04-10
JPH11513252A (en) 1999-11-16
AU3953895A (en) 1997-04-28

Similar Documents

Publication Publication Date Title
EP0642589A4 (en) Method and reagent for inhibiting viral replication.
AU1566595A (en) Method and reagent for inhibiting hepatitis c virus replication
AU587515B2 (en) Truss systems and components thereof
GB9509983D0 (en) Replication of data
ZA944488B (en) System for viral inactivation of blood
GB8818689D0 (en) Corona discharge treated release sheets
AU1648488A (en) Multiply folded laser systems
HUP9603071A2 (en) Purin-6-one derivatives and pharmaceuticals preparations containing them
AU6774294A (en) Methods of preventing viral replication
GB9215540D0 (en) Protein expression system
AU3731293A (en) Protein kinase c inhibitor
AU1905399A (en) Hepatitis c virus ns5b truncated protein and methods thereof to identify antiviral compounds
GB2259705B (en) Polypeptide inhibitor of viral replication
AU4772493A (en) Sulfo-derivatives of adenosine
IL87977A0 (en) Separation of gases
AU4248297A (en) Inhibition of viral replication
AU6595986A (en) Aids virus gene expression
EP0710286A4 (en) Methods and dna expression systems for over-expression of proteins in host cells
GB9215541D0 (en) Protein expression system
AU4166997A (en) Use of herpes simplex virus orf p protein in repression of viral protein synthesis and related methods
EP0861322A4 (en) Antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for replication
AU5676096A (en) Chimeric nucleic acids and proteins for inhibiting hiv-1 exp ression
AU4508493A (en) Therapeutic nucleosides
HUP9602220A2 (en) Substituted 4h-piranes and pharmaceutical preparations containing them
AU6158696A (en) Di- and tri-aminoguanidines and their use to inhibit the advanced glycosylation of proteins

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19980416

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20020510

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20020823

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20030303