EP0842187A4 - Human cystatin e - Google Patents

Human cystatin e

Info

Publication number
EP0842187A4
EP0842187A4 EP95922973A EP95922973A EP0842187A4 EP 0842187 A4 EP0842187 A4 EP 0842187A4 EP 95922973 A EP95922973 A EP 95922973A EP 95922973 A EP95922973 A EP 95922973A EP 0842187 A4 EP0842187 A4 EP 0842187A4
Authority
EP
European Patent Office
Prior art keywords
human cystatin
cystatin
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95922973A
Other languages
German (de)
French (fr)
Other versions
EP0842187A1 (en
Inventor
Jian Ni
Guo-Liang Yu
Reiner Gentz
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0842187A1 publication Critical patent/EP0842187A1/en
Publication of EP0842187A4 publication Critical patent/EP0842187A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
EP95922973A 1995-06-05 1995-06-05 Human cystatin e Withdrawn EP0842187A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002223888A CA2223888A1 (en) 1995-06-05 1995-06-05 Human cystatin e
PCT/US1995/007135 WO1996039418A1 (en) 1995-06-05 1995-06-05 Human cystatin e

Publications (2)

Publication Number Publication Date
EP0842187A1 EP0842187A1 (en) 1998-05-20
EP0842187A4 true EP0842187A4 (en) 2000-04-12

Family

ID=25679905

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95922973A Withdrawn EP0842187A4 (en) 1995-06-05 1995-06-05 Human cystatin e

Country Status (3)

Country Link
EP (1) EP0842187A4 (en)
CA (1) CA2223888A1 (en)
WO (1) WO1996039418A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869259A (en) * 1997-06-09 1999-02-09 Incyte Pharmaceuticals, Inc. Carboxypeptidase inhibitor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009384A1 (en) * 1987-05-22 1988-12-01 Novo-Nordisk A/S Method of producing cystatin c or modifications hereof and dna-sequence for use when carrying out the method
EP0373771A2 (en) * 1988-11-18 1990-06-20 Taisho Pharmaceutical Co. Ltd New pharmaceutical uses for cystatins
JPH07126294A (en) * 1993-04-28 1995-05-16 Snow Brand Milk Prod Co Ltd New cysteine protease inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432264A (en) * 1987-05-22 1995-07-11 Novo Nordisk A/S Recombinant 3-des-OH-cystatin C produced by expression in a procaryotic host cell
US5212297A (en) * 1989-05-16 1993-05-18 University Of Kansas cDNA clones encoding chicken egg white cystatin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009384A1 (en) * 1987-05-22 1988-12-01 Novo-Nordisk A/S Method of producing cystatin c or modifications hereof and dna-sequence for use when carrying out the method
EP0373771A2 (en) * 1988-11-18 1990-06-20 Taisho Pharmaceutical Co. Ltd New pharmaceutical uses for cystatins
JPH07126294A (en) * 1993-04-28 1995-05-16 Snow Brand Milk Prod Co Ltd New cysteine protease inhibitor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
NI J ET AL: "Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.", JOURNAL OF BIOLOGICAL CHEMISTRY, (1997 APR 18) 272 (16) 10853-8., XP002130248 *
See also references of WO9639418A1 *
SNOW BRAND MILK PROD CO LTD: "WPI WORLD PATENT INFORMATION DERWENT,GB,DERWENT", WPI WORLD PATENT INFORMATION DERWENT,GB,DERWENT, VOL. 28, NR. 95, XP002031097 *
SOTIROPOULOU G ET AL: "Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer.", JOURNAL OF BIOLOGICAL CHEMISTRY, (1997 JAN 10) 272 (2) 903-10., XP002130249 *

Also Published As

Publication number Publication date
EP0842187A1 (en) 1998-05-20
WO1996039418A1 (en) 1996-12-12
CA2223888A1 (en) 1996-12-12

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