EP0833835A4 - Obesity protein intermediates and their preparation and use - Google Patents

Obesity protein intermediates and their preparation and use

Info

Publication number
EP0833835A4
EP0833835A4 EP96921702A EP96921702A EP0833835A4 EP 0833835 A4 EP0833835 A4 EP 0833835A4 EP 96921702 A EP96921702 A EP 96921702A EP 96921702 A EP96921702 A EP 96921702A EP 0833835 A4 EP0833835 A4 EP 0833835A4
Authority
EP
European Patent Office
Prior art keywords
preparation
obesity protein
protein intermediates
intermediates
obesity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP96921702A
Other languages
German (de)
French (fr)
Other versions
EP0833835A1 (en
Inventor
John Edward Hale
Warren Cameron Mackellar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP0833835A1 publication Critical patent/EP0833835A1/en
Publication of EP0833835A4 publication Critical patent/EP0833835A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Child & Adolescent Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP96921702A 1995-06-22 1996-06-20 Obesity protein intermediates and their preparation and use Ceased EP0833835A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45195P 1995-06-22 1995-06-22
US451 1995-06-22
PCT/US1996/010613 WO1997000886A1 (en) 1995-06-22 1996-06-20 Obesity protein intermediates and their preparation and use

Publications (2)

Publication Number Publication Date
EP0833835A1 EP0833835A1 (en) 1998-04-08
EP0833835A4 true EP0833835A4 (en) 1999-05-26

Family

ID=21691591

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96921702A Ceased EP0833835A4 (en) 1995-06-22 1996-06-20 Obesity protein intermediates and their preparation and use

Country Status (5)

Country Link
EP (1) EP0833835A4 (en)
JP (1) JPH11508134A (en)
AU (1) AU6284896A (en)
CA (1) CA2224867A1 (en)
WO (1) WO1997000886A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2217698A1 (en) * 1996-12-20 1998-06-20 Eli Lilly And Company Anti-obesity proteins
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
DE10059336A1 (en) * 2000-11-29 2002-06-13 Scil Proteins Gmbh Production of recombinant BMP-2
DK2219031T3 (en) 2001-10-22 2013-06-17 Amgen Inc Use of leptin for the treatment of human lipoatrophy and method for determining predisposition to the treatment gene
WO2010118384A2 (en) 2009-04-10 2010-10-14 Amylin Pharmaceuticals, Inc. Amylin agonist compounds for estrogen-deficient mammals
PT2621519T (en) 2010-09-28 2017-10-04 Aegerion Pharmaceuticals Inc Leptin-abd fusion polypeptides with enhanced duration of action

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994018227A2 (en) * 1993-02-04 1994-08-18 Denzyme Aps Improved method for the refolding of proteins
WO1996005309A2 (en) * 1994-08-17 1996-02-22 The Rockefeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
WO1996027385A1 (en) * 1995-03-03 1996-09-12 Eli Lilly And Company Anti-obesity proteins
WO1996034885A2 (en) * 1995-05-05 1996-11-07 Smithkline Beecham Plc Biologically active peptide fragments of ob protein
WO1997006816A1 (en) * 1995-08-17 1997-02-27 Amgen Inc. Methods of reducing or maintaining reduced levels of blood lipids using ob protein compositions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994018227A2 (en) * 1993-02-04 1994-08-18 Denzyme Aps Improved method for the refolding of proteins
WO1996005309A2 (en) * 1994-08-17 1996-02-22 The Rockefeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
WO1996027385A1 (en) * 1995-03-03 1996-09-12 Eli Lilly And Company Anti-obesity proteins
WO1996034885A2 (en) * 1995-05-05 1996-11-07 Smithkline Beecham Plc Biologically active peptide fragments of ob protein
WO1997006816A1 (en) * 1995-08-17 1997-02-27 Amgen Inc. Methods of reducing or maintaining reduced levels of blood lipids using ob protein compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MURAKAMI T ET AL: "CLONING OF RAT OBESE CDNA AND ITS EXPRESSION IN OBESE RATS", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 209, no. 3, 26 April 1995 (1995-04-26), pages 944 - 952, XP002003621 *
See also references of WO9700886A1 *

Also Published As

Publication number Publication date
CA2224867A1 (en) 1997-01-09
AU6284896A (en) 1997-01-22
WO1997000886A1 (en) 1997-01-09
EP0833835A1 (en) 1998-04-08
JPH11508134A (en) 1999-07-21

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