EP0830375A4 - Human inhibitor of apoptosis gene 1 - Google Patents

Human inhibitor of apoptosis gene 1

Info

Publication number
EP0830375A4
EP0830375A4 EP95919804A EP95919804A EP0830375A4 EP 0830375 A4 EP0830375 A4 EP 0830375A4 EP 95919804 A EP95919804 A EP 95919804A EP 95919804 A EP95919804 A EP 95919804A EP 0830375 A4 EP0830375 A4 EP 0830375A4
Authority
EP
European Patent Office
Prior art keywords
apoptosis gene
human inhibitor
inhibitor
human
apoptosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95919804A
Other languages
German (de)
French (fr)
Other versions
EP0830375A1 (en
Inventor
Wei Wu He
Peter L Hudson
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0830375A1 publication Critical patent/EP0830375A1/en
Publication of EP0830375A4 publication Critical patent/EP0830375A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP95919804A 1995-05-11 1995-05-11 Human inhibitor of apoptosis gene 1 Withdrawn EP0830375A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/005922 WO1996035703A1 (en) 1995-05-11 1995-05-11 Human inhibitor of apoptosis gene 1
CA002220670A CA2220670A1 (en) 1995-05-11 1995-05-11 Human inhibitor of apoptosis gene 1

Publications (2)

Publication Number Publication Date
EP0830375A1 EP0830375A1 (en) 1998-03-25
EP0830375A4 true EP0830375A4 (en) 2001-11-21

Family

ID=25679809

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95919804A Withdrawn EP0830375A4 (en) 1995-05-11 1995-05-11 Human inhibitor of apoptosis gene 1

Country Status (4)

Country Link
EP (1) EP0830375A4 (en)
AU (1) AU2548095A (en)
CA (1) CA2220670A1 (en)
WO (1) WO1996035703A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156535A (en) 1995-08-04 2000-12-05 University Of Ottawa Mammalian IAP gene family, primers, probes, and detection methods
AUPN727595A0 (en) * 1995-12-22 1996-01-18 Walter And Eliza Hall Institute Of Medical Research, The Therapeutic compositions
US6133437A (en) * 1997-02-13 2000-10-17 Apoptogen, Inc. Modulation of IAPs for the treatment of proliferative diseases
AU5065098A (en) * 1996-11-15 1998-06-10 University Of Ottawa Modulators of ovarial apoptosis related to iap
US6472172B1 (en) * 1998-07-31 2002-10-29 Schering Aktiengesellschaft DNA encoding a novel human inhibitor-of-apoptosis protein
EP1161546A2 (en) * 1998-10-30 2001-12-12 University of Nebraska-Lincoln Trans-species transfer of apoptotic genes and transgenic plants developed thereby
AU5544500A (en) 1999-06-15 2001-01-02 Astrazeneca Ab Livin; inhibitor-of-apoptosis protein-3 (iap-3)
JP4486365B2 (en) 2002-03-27 2010-06-23 エーゲーラ セラピューティクス インコーポレイテッド Antisense IAP nucleobase oligomers and uses thereof
US8012944B2 (en) 2003-10-30 2011-09-06 Pharmascience Inc. Method for treating cancer using IAP antisense oligomer and chemotherapeutic agent

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DUCKETT C S ET AL: "A CONSERVED FAMILY OF CELLULAR GENES RELATED TO THE BACULOVIRUS IAP GENE AND ENCODING APOPTOSIS INHIBITORS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 15, no. 11, 1996, pages 2685 - 2694, XP002032297, ISSN: 0261-4189 *
LISTON P ET AL: "SUPPRESSION OF APOPTOSIS IN MAMMALIAN CELLS BY NAIP AND A RELATED FAMILY OF IAP GENES", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 379, no. 6563, 25 January 1996 (1996-01-25), pages 349 - 353, XP002032296, ISSN: 0028-0836 *
RAJCAN-SEPAROVIC ET AL: "Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 37, no. 3, 1 November 1996 (1996-11-01), pages 404 - 406, XP002121939, ISSN: 0888-7543 *
ROTHE M ET AL: "THE TNFR2-TRAF SIGNALING COMPLEX CONTAINS TWO NOVEL PROTEINS RELATED TO BACULOVIRAL INHIBITOR OF APOPTOSIS PROTEINS", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 83, no. 7, 29 December 1995 (1995-12-29), pages 1243 - 1252, XP002032302, ISSN: 0092-8674 *
ROY N ET AL: "THE GENE FOR NEURONAL APOPTOSIS INHIBITORY PROTEIN IS PARTIALLY DELETED IN INDIVIDUALS WITH SPINAL MUSCULAR ATROPHY", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 80, no. 1, 13 January 1995 (1995-01-13), pages 167 - 178, XP002032295, ISSN: 0092-8674 *
See also references of WO9635703A1 *
UREN A G ET AL: "CLONING AND EXPRESSION O FAPOPTOSIS INHIBITORY PROTEIN HOMOLOGS THAT FUNCTION TO INHIBIT APOPTOSIS AND/OR BIND TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTORS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, May 1996 (1996-05-01), pages 4974 - 4978, XP000918891, ISSN: 0027-8424 *
VAUX D L: "TOWARD AN UNDERSTANDING OF THE MOLECULAR MECHANISMS OF PHYSIOLOGICAL CELL DEATH", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 90, February 1993 (1993-02-01), pages 786 - 789, XP000918873, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
CA2220670A1 (en) 1996-11-14
WO1996035703A1 (en) 1996-11-14
EP0830375A1 (en) 1998-03-25
AU2548095A (en) 1996-11-29

Similar Documents

Publication Publication Date Title
IL118101A0 (en) Inhibitors of farnesyltransferase
PL327569A1 (en) Promedications of thrombosin inhibitors
GB9514437D0 (en) Inhibition of gene expression
SI1445259T1 (en) Use of crystal forms of 2-methyl-thieno-benzodiazepine
PL322277A1 (en) Derivatives of pyrazol-4-ylobenzoyl
PL322549A1 (en) Inhibitors of proteinous farnesiltransferase
GB9526560D0 (en) Use of 2-Amino-Heterocycles
GB9514435D0 (en) Inhibition of gene expression
PL324451A1 (en) Derivatives of diphenylmethylenepiperidine
GB9512290D0 (en) Uses of polyhexanide
AU6692996A (en) Inhibitors of apoptosis
BR9607427A (en) Inhibition of angiogenes using interleukin 12
EP0830375A4 (en) Human inhibitor of apoptosis gene 1
SG42329A1 (en) Use of phenylcyclohexylcarboxamides
GB9621852D0 (en) Inhibition of scale
GB9525918D0 (en) Structure of armrest-driven wheelchair
GB9526691D0 (en) Medical use of proteases
PL325170A1 (en) Bipolar forms of throwaflocacin
EP0841910A4 (en) INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS
ZA955689B (en) Human inhibitor of apoptosis gene 1
HUT76555A (en) Derivatives of trans apovincaminic-acid-esters
PL323148A1 (en) Esters of crabapenemes
PL323141A1 (en) Esters of crabapenemes
PL319344A1 (en) Gene of human galactokinase
IL118238A0 (en) Synthesis of benzoquinolinones

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19971205

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20011005

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20030605

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20040622