EP0822978A4 - Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts - Google Patents

Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts

Info

Publication number
EP0822978A4
EP0822978A4 EP96911759A EP96911759A EP0822978A4 EP 0822978 A4 EP0822978 A4 EP 0822978A4 EP 96911759 A EP96911759 A EP 96911759A EP 96911759 A EP96911759 A EP 96911759A EP 0822978 A4 EP0822978 A4 EP 0822978A4
Authority
EP
European Patent Office
Prior art keywords
seeding
shipping
sterilizing
culturing
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96911759A
Other languages
German (de)
French (fr)
Other versions
EP0822978A1 (en
Inventor
Alvin Peterson
Lee K Landeen
Joan Zeltinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advanced Tissue Sciences Inc
Original Assignee
Advanced Tissue Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Tissue Sciences Inc filed Critical Advanced Tissue Sciences Inc
Publication of EP0822978A1 publication Critical patent/EP0822978A1/en
Publication of EP0822978A4 publication Critical patent/EP0822978A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/06—Tubular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/24—Apparatus using programmed or automatic operation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
EP96911759A 1995-04-27 1996-04-09 Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts Withdrawn EP0822978A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US430768 1989-10-31
US43076895A 1995-04-27 1995-04-27
PCT/US1996/005151 WO1996034090A1 (en) 1995-04-27 1996-04-09 Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts

Publications (2)

Publication Number Publication Date
EP0822978A1 EP0822978A1 (en) 1998-02-11
EP0822978A4 true EP0822978A4 (en) 1999-08-18

Family

ID=23708945

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96911759A Withdrawn EP0822978A4 (en) 1995-04-27 1996-04-09 Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts

Country Status (7)

Country Link
EP (1) EP0822978A4 (en)
JP (1) JP4059301B2 (en)
KR (1) KR19990008070A (en)
AU (1) AU703117B2 (en)
CA (1) CA2219202A1 (en)
NZ (1) NZ306304A (en)
WO (1) WO1996034090A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
EP2075015B1 (en) * 1997-07-03 2015-03-11 Massachusetts Institute of Technology Tissue-engineered constructs
US6066495A (en) * 1998-03-05 2000-05-23 Tissue Engineering, Inc. Methods and apparatus for the conditioning of ligament replacement tissue
WO2002032224A1 (en) * 2000-10-06 2002-04-25 Dancu Michael B System and method to simulate hemodynamics
EP1205541A1 (en) * 2000-11-14 2002-05-15 Klaus Dr. Giehl Procedure for the long-term cultivation of organo-typic slices of brain and other postnatal tissues, in particular of adult mammals
JP2002315566A (en) 2001-04-24 2002-10-29 Takagi Ind Co Ltd Cell and tissue-culturing apparatus
JP2003061642A (en) * 2001-08-30 2003-03-04 Takagi Ind Co Ltd Cell and tissue-culturing device
EP1495108A2 (en) * 2002-04-08 2005-01-12 Millenium Biologix Inc. Automated tissue engineering system
JP4061149B2 (en) * 2002-07-24 2008-03-12 株式会社ティッシュエンジニアリングイニシアティブ Cell culture device and cell culture method
JP2006223317A (en) * 2003-05-15 2006-08-31 Univ Waseda Method of cell seeding
JP2006223101A (en) * 2003-05-15 2006-08-31 Univ Waseda Living organism tissue retaining unit and living organism tissue treating apparatus including the same
GB0410177D0 (en) * 2004-05-07 2004-06-09 Univ Wales Medicine Engineered tubular tissue structures
DE102005049905A1 (en) * 2005-10-17 2007-04-19 Medizinische Hochschule Hannover Method and device for producing a joint replacement
JP5433129B2 (en) 2006-07-10 2014-03-05 パーパス株式会社 Cell or tissue culture method
JP4981374B2 (en) 2006-07-10 2012-07-18 パーパス株式会社 Cell or tissue culture apparatus and culture method
AU2007283465A1 (en) * 2006-08-11 2008-02-14 The University Of Queensland Scaffold treatment - device and method
US8058057B2 (en) * 2008-05-30 2011-11-15 Corning Incorporated Cell culture apparatus and method
SG184798A1 (en) * 2010-05-17 2012-11-29 Univ Yale System for seeding cells onto three dimensional scaffolds
US9090863B2 (en) 2010-05-17 2015-07-28 Pall Corporation System for seeding cells onto three dimensional scaffolds
CN105296433B (en) 2014-08-01 2018-02-09 中山康方生物医药有限公司 A kind of CTLA4 antibody, its medical composition and its use
KR102231394B1 (en) 2016-05-19 2021-03-24 코지 사이토 Culture apparatus and culture method, and culture organs produced by the culture method
GB2554635A (en) * 2016-08-03 2018-04-11 Northwick Park Institute For Medical Res Ltd Bioreactors and methods for processing biological material
WO2018035710A1 (en) 2016-08-23 2018-03-01 Akeso Biopharma, Inc. Anti-ctla4 antibodies
US20200078160A1 (en) * 2016-11-07 2020-03-12 Sharklet Technologies, Inc. Vascular grafts, method of manufacturing thereof and articles comprising the same
WO2021111642A1 (en) * 2019-12-06 2021-06-10 ティシューバイネット株式会社 Method for culturing tubular cell structure
CA3189196A1 (en) * 2020-07-09 2022-01-13 Novoheart International Limited Support and system for engineered tissue

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265176A2 (en) * 1986-10-20 1988-04-27 Malcolm B. Herring Endothelial cell seeder, method and kit for seeding endothelial cells
EP0320441A1 (en) * 1987-12-07 1989-06-14 GebràœDer Sulzer Aktiengesellschaft Apparatus and process for producing a plastic support coated with living cells
EP0393788A2 (en) * 1989-04-17 1990-10-24 Koken Co. Ltd. Vascular prosthesis and manufacturing method of the same
US4990131A (en) * 1987-09-01 1991-02-05 Herbert Dardik Tubular prostheses for vascular reconstructive surgery and process for preparing same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4050893A (en) * 1974-07-22 1977-09-27 Hancock Laboratories, Inc. Arrangement for preparing natural tissue for implantation
US4015590A (en) * 1976-04-12 1977-04-05 Baylor College Of Medicine Balloon activated blood pump
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
US4911713A (en) * 1986-03-26 1990-03-27 Sauvage Lester R Method of making vascular prosthesis by perfusion
CH671683A5 (en) * 1987-03-05 1989-09-29 Sulzer Ag
EP0571527B1 (en) * 1991-02-14 1996-04-24 Baxter International Inc. Method of manufacturing pliable biological graft materials
GB9116036D0 (en) * 1991-07-25 1991-09-11 Univ Leicester Preparing grafts for implantation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265176A2 (en) * 1986-10-20 1988-04-27 Malcolm B. Herring Endothelial cell seeder, method and kit for seeding endothelial cells
US4990131A (en) * 1987-09-01 1991-02-05 Herbert Dardik Tubular prostheses for vascular reconstructive surgery and process for preparing same
EP0320441A1 (en) * 1987-12-07 1989-06-14 GebràœDer Sulzer Aktiengesellschaft Apparatus and process for producing a plastic support coated with living cells
EP0393788A2 (en) * 1989-04-17 1990-10-24 Koken Co. Ltd. Vascular prosthesis and manufacturing method of the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9634090A1 *

Also Published As

Publication number Publication date
JP4059301B2 (en) 2008-03-12
EP0822978A1 (en) 1998-02-11
WO1996034090A1 (en) 1996-10-31
CA2219202A1 (en) 1996-10-31
JPH11504216A (en) 1999-04-20
AU703117B2 (en) 1999-03-18
AU5484396A (en) 1996-11-18
KR19990008070A (en) 1999-01-25
NZ306304A (en) 1999-03-29

Similar Documents

Publication Publication Date Title
NZ306304A (en) Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native vascular grafts
AU5931896A (en) Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs
IL144187A0 (en) Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic, or native vascular grafts
GB2215209B (en) Method and apparatus for biodegradable, osteogenic, bone graft substitute device
AU4969990A (en) Stabilized sterilizing or disinfecting halogen containing composition, method and apparatus
AU1808197A (en) Medical stents, apparatus and method for making same
EP0720450A4 (en) Apparatus and method for surgically securing bone parts
DE69633888D1 (en) Osteoinductive product, process for its preparation and bone filler based thereon
AU649495B2 (en) Method and apparatus for tipping sutures
DE59607959D1 (en) INTERVOLBLE IMPLANT AND INSTRUMENTS FOR IMPLANTING AN INTERVOLBLE IMPLANT
FR2706768B1 (en)
MX9802949A (en) Method of and package for sterilized edible material.
AU6531998A (en) Method and apparatus for sterilizing packaging
EP0748612A3 (en) Surgical suturing apparatus
HU9601464D0 (en) Sanitary absorbent article, method and apparatus for packing thereof
DE69622705D1 (en) CARRIER FOR STERILIZATION AND CONTAINER SYSTEM FOR STORAGE
AU678727B2 (en) Spray-type sterilizer apparatus and sterilizing method
AU2825992A (en) Method and container for sterilizing or disinfecting
EP0478115A3 (en) Sterilant mixture and sterilization method
EP0797384A4 (en) Organ transplant solutions and method for transplanting an organ
IL124927A0 (en) Preservation solution
DE69628991D1 (en) Foamy acidified food and process for making it
AU6284490A (en) Apparatus and method for preserving and transporting body organs and tissues
GB9504830D0 (en) Surgical instrument sterilising tray
AU2057297A (en) Method and apparatus for disinfecting medical instruments

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19971104

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19990705

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 6C 12M 3/00 A, 6A 61F 2/06 B, 6A 61L 27/00 B, 6A 61L 2/24 B

17Q First examination report despatched

Effective date: 20001018

GRAH Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOS IGRA

GRAH Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOS IGRA

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20031031