EP0815137A4 - Menschlicher g-protein chemokinrezeptor hdgnr10 - Google Patents

Menschlicher g-protein chemokinrezeptor hdgnr10

Info

Publication number
EP0815137A4
EP0815137A4 EP95921613A EP95921613A EP0815137A4 EP 0815137 A4 EP0815137 A4 EP 0815137A4 EP 95921613 A EP95921613 A EP 95921613A EP 95921613 A EP95921613 A EP 95921613A EP 0815137 A4 EP0815137 A4 EP 0815137A4
Authority
EP
European Patent Office
Prior art keywords
human
chemokine receptor
protein chemokine
hdgnr10
receptor hdgnr10
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95921613A
Other languages
English (en)
French (fr)
Other versions
EP0815137A1 (de
Inventor
Yi Li
Steven M Ruben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Priority to EP01108492A priority Critical patent/EP1146122A3/de
Priority to EP01108493A priority patent/EP1149582A3/de
Priority to EP01108496A priority patent/EP1146055A3/de
Priority to EP01108491A priority patent/EP1148126A3/de
Priority to EP01108495A priority patent/EP1148127A3/de
Priority to EP01108494A priority patent/EP1145721A3/de
Publication of EP0815137A1 publication Critical patent/EP0815137A1/de
Publication of EP0815137A4 publication Critical patent/EP0815137A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP95921613A 1995-06-06 1995-06-06 Menschlicher g-protein chemokinrezeptor hdgnr10 Withdrawn EP0815137A4 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP01108492A EP1146122A3 (de) 1995-06-06 1995-06-06 Menschlicher G-protein chemokinrezeptor HDGNR10 (CCR5 Rezeptor)
EP01108493A EP1149582A3 (de) 1995-06-06 1995-06-06 Menschlicher G:Protein chemokinrezeptor HDGNR10 (CCR5 Rezeptor). Seine Verwendungen
EP01108496A EP1146055A3 (de) 1995-06-06 1995-06-06 Antikörper gegen Menschlichen G-Protein chemokinrezeptor HDGNR10 (CCR5 Rezeptor)
EP01108491A EP1148126A3 (de) 1995-06-06 1995-06-06 Menschlicher G-Protein ChemokinRezeptor HDGNR10 (CCR5 Rezeptor)
EP01108495A EP1148127A3 (de) 1995-06-06 1995-06-06 Menschlicher G-Protein ChemokinRezeptor HDGNR10 (CCR5 Rezeptor). Seine verwendungen
EP01108494A EP1145721A3 (de) 1995-06-06 1995-06-06 Menschlicher G-protein chemokinrezeptor DHDGNR10 (CCR5 Rezeptor). Pharmazeutische Zusammenstellung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/007173 WO1996039437A1 (en) 1995-06-06 1995-06-06 Human g-protein chemokine receptor hdgnr10
CA002216990A CA2216990A1 (en) 1995-06-06 1997-11-27 Human g-protein chemokine receptor hdgnr10

Related Child Applications (6)

Application Number Title Priority Date Filing Date
EP01108492A Division EP1146122A3 (de) 1995-06-06 1995-06-06 Menschlicher G-protein chemokinrezeptor HDGNR10 (CCR5 Rezeptor)
EP01108493A Division EP1149582A3 (de) 1995-06-06 1995-06-06 Menschlicher G:Protein chemokinrezeptor HDGNR10 (CCR5 Rezeptor). Seine Verwendungen
EP01108496A Division EP1146055A3 (de) 1995-06-06 1995-06-06 Antikörper gegen Menschlichen G-Protein chemokinrezeptor HDGNR10 (CCR5 Rezeptor)
EP01108494A Division EP1145721A3 (de) 1995-06-06 1995-06-06 Menschlicher G-protein chemokinrezeptor DHDGNR10 (CCR5 Rezeptor). Pharmazeutische Zusammenstellung
EP01108495A Division EP1148127A3 (de) 1995-06-06 1995-06-06 Menschlicher G-Protein ChemokinRezeptor HDGNR10 (CCR5 Rezeptor). Seine verwendungen
EP01108491A Division EP1148126A3 (de) 1995-06-06 1995-06-06 Menschlicher G-Protein ChemokinRezeptor HDGNR10 (CCR5 Rezeptor)

Publications (2)

Publication Number Publication Date
EP0815137A1 EP0815137A1 (de) 1998-01-07
EP0815137A4 true EP0815137A4 (de) 1998-08-05

Family

ID=25679666

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95921613A Withdrawn EP0815137A4 (de) 1995-06-06 1995-06-06 Menschlicher g-protein chemokinrezeptor hdgnr10

Country Status (5)

Country Link
EP (1) EP0815137A4 (de)
JP (1) JPH10510719A (de)
AU (1) AU2663295A (de)
CA (1) CA2216990A1 (de)
WO (1) WO1996039437A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
ES2325042T3 (es) 1995-06-07 2009-08-24 Progenics Pharmaceuticals, Inc. Anticuerpo monoclonal para inhibir la fusion de membrana mediada por glicoproteina de la envoltura de vih-1.
US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
US7118859B2 (en) 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
EP2034023A1 (de) 1996-03-01 2009-03-11 Euroscreen S.A. CC-Chemokinzeptor C-C CKR-5, dessen Derivate und Verwendungen
US7858298B1 (en) 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
CA2252432A1 (en) * 1996-04-26 1997-11-06 Incyte Pharmaceuticals, Inc. Mammalian mixed lymphocyte receptors, chemokine receptors [mmlr-ccr]
WO1997045543A2 (en) * 1996-05-28 1997-12-04 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health Cc chemokine receptor 5, antibodies thereto, transgenic animals
JP4183754B2 (ja) * 1996-06-14 2008-11-19 プロジェニクス・ファーマスーティカルス・インコーポレーテッド Ｈｉｖ―１感染を阻害するためのケモカイン受容体の使用
US5928881A (en) * 1996-07-11 1999-07-27 Smithkline Beecham Corporation Method of identifying agonists and antagonist for CC-CKR5 receptor
US6388055B1 (en) 1996-10-03 2002-05-14 Smithkline Beecham Corporation Mouse CC-CKR5 receptor polypeptide
US6528625B1 (en) 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same
US6153431A (en) * 1997-05-30 2000-11-28 Fond Mondiale Rech & Prev Sida Human immunodeficiency virus co-receptor variants associated with resistance to virus infection
US6204024B1 (en) 1997-09-12 2001-03-20 Akzo Nobel N.V. CCR5 RNA transcription based amplification assay
US6383746B1 (en) 1997-10-23 2002-05-07 The United States Of America As Represented By The Department Of Health And Human Services Functional promoter for CCR5
US6287805B1 (en) 1998-03-20 2001-09-11 Millennium Pharmaceuticals, Inc. Nucleic acid molecules of the protein-coupled heptahelical receptor superfamily and uses therefor
KR20030032916A (ko) * 2000-02-09 2003-04-26 휴먼 게놈 사이언시즈, 인크. Ｃｃｒ5에 대한 항체
JP2004500113A (ja) * 2000-03-27 2004-01-08 ピーイー　コーポレーション　（エヌワイ） 単離ヒトｇタンパク質共役受容体、ヒトｇｐｃｒタンパク質をコード化している核酸分子、及びそれらの使用
US7138119B2 (en) 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7175988B2 (en) 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
US7393934B2 (en) 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
EP1723178A4 (de) 2004-03-12 2007-12-12 Human Genome Sciences Inc Humaner g-protein-chemokinrezeptor (ccr5) hdgnr10
US20070026441A1 (en) 2005-07-22 2007-02-01 Olson William C Methods for reducing viral load in HIV-1-infected patients

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019436A1 (en) * 1994-01-13 1995-07-20 The Regents Of The University Of California Mammalian monocyte chemoattractant protein receptors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019436A1 (en) * 1994-01-13 1995-07-20 The Regents Of The University Of California Mammalian monocyte chemoattractant protein receptors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHARO I F ET AL: "MOLECULAR CLONING AND FUNCTIONAL EXPRESSION OF TWO MONOCYTE CHEMOATTRACTANT PROTEIN 1 RECEPTORS REVEALS ALTERNATIVE SPLICING OFTHE CARBOXYL-TERMINAL TAILS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 91, 1 March 1994 (1994-03-01), pages 2752 - 2756, XP000571082 *
See also references of WO9639437A1 *
YAMAGAMI S ET AL: "CDNA CLONING AND FUNCTIONAL EXPRESSION OF A HUMAN MONOCYTE CHEMOATTRACTANT PROTEIN 1 RECEPTOR", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 202, no. 2, 29 July 1994 (1994-07-29), pages 1156 - 1162, XP000571066 *

Also Published As

Publication number Publication date
WO1996039437A1 (en) 1996-12-12
JPH10510719A (ja) 1998-10-20
CA2216990A1 (en) 1997-12-27
AU2663295A (en) 1996-12-24
EP0815137A1 (de) 1998-01-07

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19970718

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Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

RHK1 Main classification (correction)

Ipc: C12N 15/12

17Q First examination report despatched

Effective date: 19981028

RIN1 Information on inventor provided before grant (corrected)

Inventor name: RUBEN, STEVEN, M.

Inventor name: LI, YI

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20010405

RIN1 Information on inventor provided before grant (corrected)

Inventor name: RUBEN, STEVEN, M.

Inventor name: LI, YI