EP0794782A4 - Cobalt schiff base compounds - Google Patents

Cobalt schiff base compounds

Info

Publication number
EP0794782A4
EP0794782A4 EP95944118A EP95944118A EP0794782A4 EP 0794782 A4 EP0794782 A4 EP 0794782A4 EP 95944118 A EP95944118 A EP 95944118A EP 95944118 A EP95944118 A EP 95944118A EP 0794782 A4 EP0794782 A4 EP 0794782A4
Authority
EP
European Patent Office
Prior art keywords
schiff base
base compounds
cobalt schiff
cobalt
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95944118A
Other languages
German (de)
French (fr)
Other versions
EP0794782A1 (en
Inventor
Thomas J Meade
Harry B Gray
Toshihiko Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Publication of EP0794782A1 publication Critical patent/EP0794782A1/en
Publication of EP0794782A4 publication Critical patent/EP0794782A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C251/12—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton being acyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C251/16—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/06—Cobalt compounds
    • C07F15/065—Cobalt compounds without a metal-carbon linkage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/06—Chelate

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
EP95944118A 1994-12-15 1995-12-14 Cobalt schiff base compounds Withdrawn EP0794782A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35806894A 1994-12-15 1994-12-15
US358068 1994-12-15
PCT/US1995/016377 WO1996018402A1 (en) 1994-12-15 1995-12-14 Cobalt schiff base compounds
1996-11-18

Publications (2)

Publication Number Publication Date
EP0794782A1 EP0794782A1 (en) 1997-09-17
EP0794782A4 true EP0794782A4 (en) 1999-04-14

Family

ID=23408160

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95944118A Withdrawn EP0794782A4 (en) 1994-12-15 1995-12-14 Cobalt schiff base compounds

Country Status (5)

Country Link
US (1) US6008190A (en)
EP (1) EP0794782A4 (en)
JP (1) JP2002515010A (en)
CA (1) CA2207748A1 (en)
WO (1) WO1996018402A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008190A (en) * 1994-12-15 1999-12-28 California Institute Of Technology Cobalt Schiff base compounds
US5693515A (en) * 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US6255091B1 (en) 1995-04-28 2001-07-03 Axys Pharmaceuticals, Inc. Potentiating metal mediated serine protease inhibitors with cobalt or zinc ions
IL124844A0 (en) * 1995-12-12 1999-01-26 California Inst Of Techn Cobalt schiff base compounds
WO1999003877A1 (en) * 1997-07-16 1999-01-28 California Institute Of Technology Methods of unfolding proteins using metal complexes
US6756368B1 (en) 1999-07-16 2004-06-29 The Trustees Of Columbia University In The City Of New York Use of cobalt chelates for treating or preventing virus infection
WO2001005396A1 (en) * 1999-07-16 2001-01-25 The Trustees Of Columbia University In The City Of New York Use of cobalt chelates for treating or preventing virus infection
US6780856B2 (en) * 2000-04-07 2004-08-24 California Institute Of Technology Towards increased shelf life for cobalt(III) schiff base complexes
WO2002008286A2 (en) * 2000-07-21 2002-01-31 Syngenta Participations Ag Zinc finger domain recognition code and uses thereof
US20030082561A1 (en) * 2000-07-21 2003-05-01 Takashi Sera Zinc finger domain recognition code and uses thereof
US7709460B2 (en) * 2001-04-25 2010-05-04 Cobalz Limited Method for treating or preventing a functional vitamin B12 deficiency in an individual and medical compositions for use in said method
JP2003146978A (en) * 2001-09-03 2003-05-21 Kyushu Univ METHOD FOR PRODUCING OPTICALLY ACTIVE LACTONE COMPOUND USING SALEN COBALT COMPLEX HAVING CIS-beta STRUCTURE
AU2002367173A1 (en) * 2001-12-21 2003-07-15 Achillion Pharmaceuticals, Inc. Antifungal compositions
US7101676B2 (en) * 2002-01-11 2006-09-05 Douglas Buechter Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA
WO2010111257A2 (en) * 2009-03-23 2010-09-30 Northwestern University Targeted schiff base complexes
JP6017766B2 (en) * 2011-07-26 2016-11-02 株式会社Ihi Novel anticancer agent of metal salen complex compound
CN102408453B (en) * 2011-09-20 2014-01-01 聊城大学 Salicylaldehyde Schiff base binuclear cobalt coordination compound and preparation method and application thereof
JP6046338B2 (en) * 2011-10-27 2016-12-14 株式会社Ihi Radical inhibitor
CN105753908A (en) * 2016-03-23 2016-07-13 桂林理工大学 Synthesis method and application of Co (mtyp)2 with anticancer activity
CN113105511A (en) * 2021-04-15 2021-07-13 南开大学 Method for generating hydroxyl free radicals by using Schiff base cobalt complex

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866053A (en) * 1986-05-13 1989-09-12 Chai-Tech Corporation Method of treating a burn employing a metallo-organic cobalt compound
US4948506A (en) * 1986-07-07 1990-08-14 Bend Research, Inc. Physicochemically functional ultrathin films by interfacial polymerization
US5049557A (en) * 1986-05-13 1991-09-17 Chai-Tech Corporation Metallo-organic salt compounds and pharmaceutical uses thereof
WO1991015212A1 (en) * 1990-03-30 1991-10-17 Chai-Tech Corporation Antiviral compositions and method for their use
WO1997021431A1 (en) * 1995-12-12 1997-06-19 California Institute Of Technology Cobalt schiff base compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451270A (en) * 1982-06-30 1984-05-29 Bend Research, Inc. Absorption process for producing oxygen and nitrogen and solution therefor
US4514522A (en) * 1984-07-27 1985-04-30 University Patents, Inc. Oxygen sorbent
US5324879A (en) * 1985-12-03 1994-06-28 Commonwealth Scientific And Industrial Research Organisation Oligomerization process
US5210096A (en) * 1986-05-13 1993-05-11 Chai-Tech Corporation Antiviral compositions and method for their use
US5142076A (en) * 1986-05-13 1992-08-25 Chai-Tech Corporation Metallo-organic salt compounds and pharmaceutical uses thereof
US4866054A (en) * 1986-05-13 1989-09-12 Chai-Tech Corporation Antioxidant metallo-organic treatment of inflammation
US4735634A (en) * 1986-08-28 1988-04-05 Air Products And Chemicals, Inc. Pillared cobalt complexes for oxygen separation
US6008190A (en) * 1994-12-15 1999-12-28 California Institute Of Technology Cobalt Schiff base compounds
EP0862574A1 (en) * 1995-09-28 1998-09-09 California Institute Of Technology Metal complexes as cysteine protease inhibitors

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866053A (en) * 1986-05-13 1989-09-12 Chai-Tech Corporation Method of treating a burn employing a metallo-organic cobalt compound
US5049557A (en) * 1986-05-13 1991-09-17 Chai-Tech Corporation Metallo-organic salt compounds and pharmaceutical uses thereof
US4948506A (en) * 1986-07-07 1990-08-14 Bend Research, Inc. Physicochemically functional ultrathin films by interfacial polymerization
WO1991015212A1 (en) * 1990-03-30 1991-10-17 Chai-Tech Corporation Antiviral compositions and method for their use
WO1997021431A1 (en) * 1995-12-12 1997-06-19 California Institute Of Technology Cobalt schiff base compounds

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 88, no. 18, 1 May 1978, Columbus, Ohio, US; abstract no. 130049, JAEGER, ERNST G. ET AL: "The effect of chelate periphery on the charge-transfer absorption of new tricyclic and macrocyclic organocobalt(III) complexes" XP002092782 *
FUJII, YUKI: "Determination of the optical purity of amino acids by complex formation. Determination of optimum condition for rotational measurement", BULL. CHEM. SOC. JPN. (1974), 47(11), 2856-61, XP002092781 *
See also references of WO9618402A1 *
Z. CHEM. (1977), 17(8), 307-8 *

Also Published As

Publication number Publication date
JP2002515010A (en) 2002-05-21
EP0794782A1 (en) 1997-09-17
WO1996018402A1 (en) 1996-06-20
CA2207748A1 (en) 1996-06-20
US6008190A (en) 1999-12-28

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Legal Events

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