EP0793490A4 - Compositions of tocopherol and beta-carotene - Google Patents

Compositions of tocopherol and beta-carotene

Info

Publication number
EP0793490A4
EP0793490A4 EP95944647A EP95944647A EP0793490A4 EP 0793490 A4 EP0793490 A4 EP 0793490A4 EP 95944647 A EP95944647 A EP 95944647A EP 95944647 A EP95944647 A EP 95944647A EP 0793490 A4 EP0793490 A4 EP 0793490A4
Authority
EP
European Patent Office
Prior art keywords
carotene
tocopherol
beta
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95944647A
Other languages
German (de)
French (fr)
Other versions
EP0793490A1 (en
Inventor
James P Clark
Manfred S Dunker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel Corp
Original Assignee
Henkel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Corp filed Critical Henkel Corp
Publication of EP0793490A1 publication Critical patent/EP0793490A1/en
Publication of EP0793490A4 publication Critical patent/EP0793490A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
EP95944647A 1994-12-22 1995-12-22 Compositions of tocopherol and beta-carotene Withdrawn EP0793490A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36161594A 1994-12-22 1994-12-22
US361615 1994-12-22
PCT/US1995/016769 WO1996019215A1 (en) 1994-12-22 1995-12-22 Compositions of tocopherol and beta-carotene

Publications (2)

Publication Number Publication Date
EP0793490A1 EP0793490A1 (en) 1997-09-10
EP0793490A4 true EP0793490A4 (en) 1999-12-15

Family

ID=23422755

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95944647A Withdrawn EP0793490A4 (en) 1994-12-22 1995-12-22 Compositions of tocopherol and beta-carotene

Country Status (4)

Country Link
EP (1) EP0793490A4 (en)
JP (1) JPH10511355A (en)
AU (1) AU702831B2 (en)
WO (1) WO1996019215A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329432B2 (en) 1993-06-28 2001-12-11 The Howard Foundation Mesozeaxanthin formulations for treatment of retinal disorders
AU705467C (en) * 1994-12-22 2002-12-19 Cognis Corporation Pharmaceutical compositions comprising lycopene
US6262109B1 (en) 1995-12-22 2001-07-17 Henkel Corporation Methods of preventing and/or treating high serum levels of cholesterol and/or lipids
AU719671B2 (en) * 1995-06-07 2000-05-18 Howard Foundation, The Pharmaceutically active carotenoids
IL121112A (en) 1997-06-19 2005-11-20 Lycored Natural Prod Ind Ltd Synergistic pharmaceutical or dietary compositionscomprising lycopene and vitamin e for preventing ldl oxidation
DE69822834T2 (en) * 1997-06-19 2005-03-24 Lycored Natural Products Industries Ltd. SYNERGISTIC COMPOSITIONS OF LYCOPINE AND VITAMIN E PREVENTING THE OXIDATION OF LDL
AU5416998A (en) * 1997-10-14 1999-05-03 Quest International B.V. Preparation for the enhancement of the antioxidant status of cells
DE19838636A1 (en) * 1998-08-26 2000-03-02 Basf Ag Carotenoid formulations containing a mixture of beta-carotene, lycopene and lutein
US6048891A (en) 1998-12-17 2000-04-11 Loma Linda University Medical Center Use of γ-tocopherol and its oxidative metabolite LLU-α in the treatment of natriuretic disease
US6582721B1 (en) * 1999-09-17 2003-06-24 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
US6350776B1 (en) 1999-09-20 2002-02-26 Angelo Manfredo Azzi Method of treating proliferative disease with lycopene and alpha-tocopherol
WO2005075575A1 (en) * 2004-02-10 2005-08-18 Nestec S.A. Compositions containing cis-isomers of a carotenoid compound and process
DE102005012831A1 (en) * 2005-03-17 2006-09-21 Schrezenmeier, Jürgen, Prof. Dr. Preparation of a medicament for lowering the risk factor of atherosclerosis and / or increasing insulin sensitivity
WO2006112906A1 (en) * 2005-04-13 2006-10-26 California Polytechnic State University Foundation Lycopene incorporation into egg yolks
ES2560666T3 (en) 2006-08-08 2016-02-22 Nestec S.A. Stable and bioavailable compositions containing carotenoid isomers for skin and hair
EP2904096A1 (en) * 2012-10-03 2015-08-12 Metabogen AB Identification of a person having risk for atherosclerosis and associated diseases by the person's gut microbiome and the prevention of such diseases

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2057463A1 (en) * 1991-12-11 1993-06-12 David Rowland Vitamin/mineral composition
FR2714292A1 (en) * 1993-12-23 1995-06-30 Synthelabo Medicaments contg. lysine acetyl-salicylate and vitamin E
EP0699437A1 (en) * 1994-08-25 1996-03-06 Prospa B.V. Pharmaceutical preparations containing polyunsaturated fatty acids, their esters or salts, together with antioxidant vitamins or provitamins
WO1997006697A1 (en) * 1995-08-21 1997-02-27 Unilever N.V. Antioxidant comprising food products

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2057463A1 (en) * 1991-12-11 1993-06-12 David Rowland Vitamin/mineral composition
FR2714292A1 (en) * 1993-12-23 1995-06-30 Synthelabo Medicaments contg. lysine acetyl-salicylate and vitamin E
EP0699437A1 (en) * 1994-08-25 1996-03-06 Prospa B.V. Pharmaceutical preparations containing polyunsaturated fatty acids, their esters or salts, together with antioxidant vitamins or provitamins
WO1997006697A1 (en) * 1995-08-21 1997-02-27 Unilever N.V. Antioxidant comprising food products

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BRATTSAND R: "Actions of vitamins A and E and some nicotinic acid derivatives on plasma lipids and on lipid infiltration of aorta in cholesterol-fed rabbits.", ATHEROSCLEROSIS, (1975 JUL-AUG) 22 (1) 47-61., XP002119576 *
BUTTURINI U: "Vitamins E and A in vascular diseases.", ACTA VITAMINOLOGICA ET ENZYMOLOGICA, (1982) 4 (1-2) 15-9. REF: 20, XP002119577 *
JIALAL I ET AL: "Effect of combined supplementation with alpha- tocopherol, ascorbate, and beta carotene on low-density lipoprotein oxidation [see comments].", CIRCULATION, (1993 DEC) 88 (6) 2780-6., XP002119578 *
KNEKT P ET AL: "Antioxidant vitamin intake and coronary mortality in a longitudinal population study.", AMERICAN JOURNAL OF EPIDEMIOLOGY, (1994 JUN 15) 139 (12) 1180-9., XP002119579 *
MEYERS D G: "The prevention of atherosclerosis with antioxidant vitamins.", KANSAS MEDICINE, (1994 JUL) 95 (7) 170-1., XP002119575 *
See also references of WO9619215A1 *
SPIRT J J ET AL: "The use of vitamin A and E in different forms of atherosclerosis.", Z GES INN MED, (1962 MAY 15) 17 431-6., XP002119580 *

Also Published As

Publication number Publication date
AU4741996A (en) 1996-07-10
JPH10511355A (en) 1998-11-04
WO1996019215A1 (en) 1996-06-27
EP0793490A1 (en) 1997-09-10
AU702831B2 (en) 1999-03-04

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Owner name: HENKEL CORPORATION

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Effective date: 19991104

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Effective date: 20010403