EP0729361A4 - Method of treating neurological disorders - Google Patents

Method of treating neurological disorders

Info

Publication number
EP0729361A4
EP0729361A4 EP95901254A EP95901254A EP0729361A4 EP 0729361 A4 EP0729361 A4 EP 0729361A4 EP 95901254 A EP95901254 A EP 95901254A EP 95901254 A EP95901254 A EP 95901254A EP 0729361 A4 EP0729361 A4 EP 0729361A4
Authority
EP
European Patent Office
Prior art keywords
neurological disorders
treating neurological
treating
disorders
neurological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95901254A
Other languages
German (de)
French (fr)
Other versions
EP0729361A1 (en
Inventor
Christopher A Maack
Debra Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celtrix Pharmaceuticals Inc
Original Assignee
Celtrix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharmaceuticals Inc filed Critical Celtrix Pharmaceuticals Inc
Publication of EP0729361A1 publication Critical patent/EP0729361A1/en
Publication of EP0729361A4 publication Critical patent/EP0729361A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
EP95901254A 1993-11-15 1994-11-15 Method of treating neurological disorders Withdrawn EP0729361A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15286893A 1993-11-15 1993-11-15
US152868 1993-11-15
PCT/US1994/013177 WO1995013823A1 (en) 1993-11-15 1994-11-15 Method of treating neurological disorders

Publications (2)

Publication Number Publication Date
EP0729361A1 EP0729361A1 (en) 1996-09-04
EP0729361A4 true EP0729361A4 (en) 1996-11-06

Family

ID=22544799

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95901254A Withdrawn EP0729361A4 (en) 1993-11-15 1994-11-15 Method of treating neurological disorders

Country Status (5)

Country Link
EP (1) EP0729361A4 (en)
JP (1) JPH09509140A (en)
AU (1) AU693489B2 (en)
CA (1) CA2176708A1 (en)
WO (1) WO1995013823A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440928B1 (en) 1988-12-06 2002-08-27 Colorado State University Research Foundation Method for treating diabetic neuropathy with NGF
ES2196194T3 (en) * 1995-12-13 2003-12-16 Aurogen Inc IGF-I AND -II INTENDED FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM.
US6514937B1 (en) 1997-02-25 2003-02-04 Celtrix Pharmaceuticals, Inc. Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3
US6015786A (en) * 1997-02-25 2000-01-18 Celtrix Pharmaceuticals, Inc. Method for increasing sex steroid levels using IGF or IGF/IGFBP-3
US6025368A (en) * 1997-02-25 2000-02-15 Celtrix Pharmaceuticals, Inc. Method for treating the symptoms of chronic stress-related disorders using IGF
JP2001514663A (en) 1997-03-12 2001-09-11 エスモンド，ロバート ダブリュー． Methods for treating or preventing Alzheimer's disease
US6417330B1 (en) 1998-06-01 2002-07-09 Celtrix Pharmaceuticals, Inc. Insulin-like growth factor binding protein variants
US6436897B2 (en) 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US7288516B1 (en) 1999-09-20 2007-10-30 Celtrix Pharmaceuticals, Inc. Null IGF for the treatment of cancer
US6040292A (en) * 1999-06-04 2000-03-21 Celtrix Pharmaceuticals, Inc. Methods for treating diabetes
AU2001291090B2 (en) 2000-09-19 2007-05-10 Bioexpertise, Llc Method for use of IGF-binding protein for selective sensitization of target cells in vivo
US7605177B2 (en) 2001-05-24 2009-10-20 Neuren Pharmaceuticals Limited Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration
US7714020B2 (en) 2001-05-24 2010-05-11 Neuren Pharmaceuticals Limited Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
ES2325983T3 (en) 2001-05-24 2009-09-28 Neuren Pharmaceuticals Limited GPE ANALOGS AND PEPTIDOMIMETICS.
US6914049B2 (en) 2001-09-18 2005-07-05 Bioexpertise, Llc IGF-binding protein-derived peptide or small molecule
US6887851B2 (en) 2001-09-18 2005-05-03 Bioexpertise, Llc IGF-binding protein-derived peptide
EP1435986B1 (en) 2001-09-18 2008-01-02 Bioexpertise, Llc Igf-binding protein-derived peptide
AU2003297259A1 (en) * 2002-11-14 2004-06-03 Wyeth Methods and compositions for treating neurological disorders
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
RU2669692C1 (en) * 2017-08-14 2018-10-15 Павел Андреевич Канаев Method for producing complex of biologically active peptides with neurotropic activity
WO2023242442A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0227619A2 (en) * 1985-12-13 1987-07-01 KabiGen AB New protein and its use
WO1993008826A1 (en) * 1991-11-08 1993-05-13 Cephalon, Inc. Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs
WO1993020836A1 (en) * 1992-04-15 1993-10-28 Cephalon, Inc. Treating disorders by application of insulin-like growth factors and analogs
WO1993025219A1 (en) * 1992-06-12 1993-12-23 Cephalon, Inc. Prevention and treatment of peripheral neuropathy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8703625D0 (en) * 1987-09-18 1987-09-18 Kabivitrum Ab NEW MEDICAL USE
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
US5093317A (en) * 1989-06-05 1992-03-03 Cephalon, Inc. Treating disorders by application of insulin-like growth factor
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
SE9101341D0 (en) * 1991-05-03 1991-05-03 Kabi Pharmacia Ab NEW MEDICINAL USE
DK0597033T3 (en) * 1991-08-01 1997-06-02 Genentech Inc IGF-1 to improve the neural state

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0227619A2 (en) * 1985-12-13 1987-07-01 KabiGen AB New protein and its use
WO1993008826A1 (en) * 1991-11-08 1993-05-13 Cephalon, Inc. Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs
WO1993020836A1 (en) * 1992-04-15 1993-10-28 Cephalon, Inc. Treating disorders by application of insulin-like growth factors and analogs
WO1993025219A1 (en) * 1992-06-12 1993-12-23 Cephalon, Inc. Prevention and treatment of peripheral neuropathy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEWIS ET AL: "THE POTENTIAL OF INSULIN-LIKE GROWTH FACTOR-I AS A THERAPEUTIC FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,USA, vol. 692, 1993, MEETING OF NOVEMBER,1992,ARLINGTON,VIRGINIA,USA, pages 201 - 208, XP002012439 *
See also references of WO9513823A1 *

Also Published As

Publication number Publication date
AU1057095A (en) 1995-06-06
JPH09509140A (en) 1997-09-16
CA2176708A1 (en) 1995-05-26
EP0729361A1 (en) 1996-09-04
WO1995013823A1 (en) 1995-05-26
AU693489B2 (en) 1998-07-02

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Inventor name: BROWN, DEBRA

Inventor name: MAACK, CHRISTOPHER A.

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STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20001214