EP0724443A4 - Methods and compositions for lowering intraocular pressure - Google Patents

Methods and compositions for lowering intraocular pressure

Info

Publication number
EP0724443A4
EP0724443A4 EP94920077A EP94920077A EP0724443A4 EP 0724443 A4 EP0724443 A4 EP 0724443A4 EP 94920077 A EP94920077 A EP 94920077A EP 94920077 A EP94920077 A EP 94920077A EP 0724443 A4 EP0724443 A4 EP 0724443A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
intraocular pressure
lowering intraocular
lowering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94920077A
Other languages
German (de)
French (fr)
Other versions
EP0724443A1 (en
Inventor
Nino Sorgente
Charles Bakhit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vide Pharmaceuticals
Original Assignee
Vide Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/096,799 external-priority patent/US5629345A/en
Application filed by Vide Pharmaceuticals filed Critical Vide Pharmaceuticals
Publication of EP0724443A1 publication Critical patent/EP0724443A1/en
Publication of EP0724443A4 publication Critical patent/EP0724443A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP94920077A 1993-06-08 1994-06-03 Methods and compositions for lowering intraocular pressure Withdrawn EP0724443A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7380293A 1993-06-08 1993-06-08
US73802 1993-06-08
US08/096,799 US5629345A (en) 1993-07-23 1993-07-23 Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
PCT/US1994/006278 WO1994028900A1 (en) 1993-06-08 1994-06-03 Methods and compositions for lowering intraocular pressure
US96799 2002-03-12

Publications (2)

Publication Number Publication Date
EP0724443A1 EP0724443A1 (en) 1996-08-07
EP0724443A4 true EP0724443A4 (en) 1997-09-10

Family

ID=26754897

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94920077A Withdrawn EP0724443A4 (en) 1993-06-08 1994-06-03 Methods and compositions for lowering intraocular pressure

Country Status (5)

Country Link
EP (1) EP0724443A4 (en)
JP (1) JPH08511024A (en)
AU (1) AU7099194A (en)
CA (1) CA2164733A1 (en)
WO (1) WO1994028900A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573758A (en) * 1995-04-28 1996-11-12 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers
ID19891A (en) * 1996-08-02 1998-08-20 Senju Pharma Co ANTI-OKULAR DISTRIBUTION COMPOSITION
DE60135972D1 (en) 2000-01-18 2008-11-13 Merck & Co Inc ORTHALMOLOGICAL COMPOSITIONS FOR THE TREATMENT OF OCULAR HYPERTENSION
US6548535B2 (en) 2000-01-18 2003-04-15 Merck & Co., Inc. Method for treating ocular hypertension
JP2005533055A (en) 2002-06-17 2005-11-04 メルク　エンド　カムパニー　インコーポレーテッド Novel maxi K channel blocker, method of use and production
JP2006510742A (en) 2002-11-08 2006-03-30 メルク　エンド　カムパニー　インコーポレーテッド Ophthalmic composition for high intraocular pressure treatment
US7196082B2 (en) 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
CN1791402A (en) 2003-03-27 2006-06-21 麦克公司 Ophthalmic compositions for treating ocular hypertension
EP1664011A4 (en) 2003-09-02 2009-02-25 Merck & Co Inc Ophthalmic compositions for treating ocular hypertension
US7410992B2 (en) 2003-09-04 2008-08-12 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
CA2537430A1 (en) 2003-09-04 2005-03-24 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
CA2574078A1 (en) 2004-07-20 2006-02-23 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171331A1 (en) * 1984-08-03 1986-02-12 Laboratoire Vaillant Defresne Liquid composition containing quinine formate
GB2177913A (en) * 1984-01-26 1987-02-04 Sanofi Sa Anti malarial compositions
EP0467710A2 (en) * 1990-07-19 1992-01-22 E.R. Squibb & Sons, Inc. Method for treating Parkinson's disease employing the ATP-sensitive potassium channel blocker quinine
EP0467709A2 (en) * 1990-07-20 1992-01-22 E.R. Squibb & Sons, Inc. Use of an ATP-sensitive potassium channel blocker to treat neuronal insult
WO1994002142A1 (en) * 1992-07-17 1994-02-03 Merck & Co., Inc. Substituted biphenylmethylimidazopyridines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895807A (en) * 1986-12-31 1990-01-23 Cherksey Bruce D Membrane channel protein and related therapeutic compounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2177913A (en) * 1984-01-26 1987-02-04 Sanofi Sa Anti malarial compositions
EP0171331A1 (en) * 1984-08-03 1986-02-12 Laboratoire Vaillant Defresne Liquid composition containing quinine formate
EP0467710A2 (en) * 1990-07-19 1992-01-22 E.R. Squibb & Sons, Inc. Method for treating Parkinson's disease employing the ATP-sensitive potassium channel blocker quinine
EP0467709A2 (en) * 1990-07-20 1992-01-22 E.R. Squibb & Sons, Inc. Use of an ATP-sensitive potassium channel blocker to treat neuronal insult
WO1994002142A1 (en) * 1992-07-17 1994-02-03 Merck & Co., Inc. Substituted biphenylmethylimidazopyridines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9428900A1 *

Also Published As

Publication number Publication date
AU7099194A (en) 1995-01-03
CA2164733A1 (en) 1994-12-22
JPH08511024A (en) 1996-11-19
EP0724443A1 (en) 1996-08-07
WO1994028900A1 (en) 1994-12-22

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Legal Events

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