EP0714506A4 - Method and instrument for automatically performing analysis relating to thrombosis and hemostasis - Google Patents

Method and instrument for automatically performing analysis relating to thrombosis and hemostasis

Info

Publication number
EP0714506A4
EP0714506A4 EP94925895A EP94925895A EP0714506A4 EP 0714506 A4 EP0714506 A4 EP 0714506A4 EP 94925895 A EP94925895 A EP 94925895A EP 94925895 A EP94925895 A EP 94925895A EP 0714506 A4 EP0714506 A4 EP 0714506A4
Authority
EP
European Patent Office
Prior art keywords
thrombosis
hemostasis
instrument
automatically performing
performing analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP94925895A
Other languages
German (de)
French (fr)
Other versions
EP0714506A1 (en
EP0714506B1 (en
Inventor
Timothy J Fischer
Janet B Callahan
Paul J Braun
Thomas B Givens
William C Hulette
Julie F Hoffman
John G Link
Charles H Swope
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux Inc
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of EP0714506A1 publication Critical patent/EP0714506A1/en
Publication of EP0714506A4 publication Critical patent/EP0714506A4/en
Application granted granted Critical
Publication of EP0714506B1 publication Critical patent/EP0714506B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00693—Calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00366—Several different temperatures used
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00693—Calibration
    • G01N2035/00702—Curve-fitting; Parameter matching; Calibration constants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G01N2035/0093—Scheduling random access not determined by physical position
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00712—Automatic status testing, e.g. at start-up or periodic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Quality & Reliability (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

This invention relates to a novel, fully automated spectrophotometric analyzer and method used for testing blood samples in the clinical laboratory for thrombosis and hemostasis properties. The analyzer tests samples in a fully randomized format, and is fully automated in the areas of specimen handling, sample preparation, optical inspection, data analysis and total quality control for imprecision and bias.
EP94925895A 1993-08-16 1994-08-16 Method and instrument for automatically performing analysis relating to thrombosis and hemostasis Expired - Lifetime EP0714506B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10738193A 1993-08-16 1993-08-16
US107381 1993-08-16
PCT/US1994/009226 WO1995005590A1 (en) 1993-08-16 1994-08-16 Method and instrument for automatically performing analysis relating to thrombosis and hemostasis

Publications (3)

Publication Number Publication Date
EP0714506A1 EP0714506A1 (en) 1996-06-05
EP0714506A4 true EP0714506A4 (en) 1997-06-18
EP0714506B1 EP0714506B1 (en) 2004-11-10

Family

ID=22316350

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94925895A Expired - Lifetime EP0714506B1 (en) 1993-08-16 1994-08-16 Method and instrument for automatically performing analysis relating to thrombosis and hemostasis

Country Status (9)

Country Link
EP (1) EP0714506B1 (en)
JP (1) JP3476826B2 (en)
KR (1) KR100321508B1 (en)
AT (1) ATE282195T1 (en)
AU (1) AU688365B2 (en)
CA (1) CA2168452A1 (en)
DE (1) DE69434128T2 (en)
FI (1) FI960682A0 (en)
WO (1) WO1995005590A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5708591A (en) * 1995-02-14 1998-01-13 Akzo Nobel N.V. Method and apparatus for predicting the presence of congenital and acquired imbalances and therapeutic conditions
US5619428A (en) * 1995-05-31 1997-04-08 Neopath, Inc. Method and apparatus for integrating an automated system to a laboratory
US6321164B1 (en) 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
US6898532B1 (en) 1995-06-07 2005-05-24 Biomerieux, Inc. Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6429017B1 (en) 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
US5879628A (en) * 1996-05-06 1999-03-09 Helena Laboratories Corporation Blood coagulation system having a bar code reader and a detecting means for detecting the presence of reagents in the cuvette
US6069011A (en) * 1997-12-10 2000-05-30 Umm Electronics, Inc. Method for determining the application of a sample fluid on an analyte strip using first and second derivatives
US6502040B2 (en) 1997-12-31 2002-12-31 Biomerieux, Inc. Method for presenting thrombosis and hemostasis assay data
JP4486260B2 (en) 1999-02-04 2010-06-23 バイオメリュー・インコーポレイテッド Method and apparatus for predicting the presence of hemostatic dysfunction in patient samples
JP3598019B2 (en) * 1999-06-16 2004-12-08 株式会社日立製作所 Automatic analyzer
US6977145B2 (en) * 1999-07-28 2005-12-20 Serono Genetics Institute S.A. Method for carrying out a biochemical protocol in continuous flow in a microreactor
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
JP2010159299A (en) * 2002-07-04 2010-07-22 Daiichi Sankyo Co Ltd Antipyretic composition comprising loxoprofen and ketotifen
JP4832121B2 (en) 2006-03-10 2011-12-07 シスメックス株式会社 Analysis system
RU2010119453A (en) * 2007-10-16 2011-11-27 Конинклейке Филипс Электроникс Н.В. (Nl) ASSESSMENT OF DIAGNOSTIC MARKERS
DE102008022884A1 (en) * 2008-05-08 2009-11-12 Zander, Rolf, Prof. Dr.Med. Device and method for blood coagulation diagnostics
ES2582205T3 (en) 2008-07-25 2016-09-09 F. Hoffmann-La Roche Ag Laboratory method and system for handling sample tube racks
US8753868B2 (en) 2008-08-04 2014-06-17 General Electric Company Method and system for selective isolation of target biological molecules in a general purpose system
US8501115B2 (en) 2008-10-24 2013-08-06 Statspin, Inc. Modular system for performing laboratory protocols and associated methods
WO2011139888A2 (en) * 2010-04-29 2011-11-10 Statspin, Inc. Analytical system for performing laboratory protocols and associated methods
CA2866854C (en) 2012-03-09 2020-08-18 Leica Biosystems Richmond, Inc. Device and method for controlling the temperature in a moving fluid in a laboratory sample processing system
EP3776574A1 (en) 2018-03-30 2021-02-17 Idexx Laboratories, Inc. Quality control for point-of-care diagnostic systems
CN108535503A (en) * 2018-07-12 2018-09-14 成都艾科斯伦医疗科技有限公司 Automatic coagulation analyzer and its application method
US11573211B2 (en) 2020-03-27 2023-02-07 Waters Technologies Corporation Sample automation manager
CN111760608B (en) * 2020-06-25 2022-04-15 杭州慈平医疗器械有限公司 Clinical laboratory is with blood sample processing apparatus after inspection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55136958A (en) * 1979-04-14 1980-10-25 Olympus Optical Co Ltd Automatic analyzer
JPS56147072A (en) * 1980-04-18 1981-11-14 Olympus Optical Co Ltd Automaic analyzing system
DE3133191C2 (en) * 1980-08-22 1986-01-16 Olympus Optical Co., Ltd., Tokio/Tokyo Automatic chemical analyzer
US4695430A (en) * 1985-10-31 1987-09-22 Bio/Data Corporation Analytical apparatus
US4958295A (en) * 1986-05-21 1990-09-18 Hercules Incorporated Analyzing apparatus and method for analysis of liquid samples
JP2649409B2 (en) * 1989-03-14 1997-09-03 株式会社日立製作所 Automated analysis methods for clinical tests

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
JP3476826B2 (en) 2003-12-10
WO1995005590A1 (en) 1995-02-23
AU688365B2 (en) 1998-03-12
AU7566394A (en) 1995-03-14
EP0714506A1 (en) 1996-06-05
DE69434128D1 (en) 2004-12-16
KR100321508B1 (en) 2002-06-24
KR960704219A (en) 1996-08-31
JPH09502021A (en) 1997-02-25
ATE282195T1 (en) 2004-11-15
FI960682A (en) 1996-02-15
EP0714506B1 (en) 2004-11-10
FI960682A0 (en) 1996-02-15
CA2168452A1 (en) 1995-02-23
DE69434128T2 (en) 2005-11-10

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