EP0713391A4 - Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes - Google Patents

Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes

Info

Publication number
EP0713391A4
EP0713391A4 EP94922684A EP94922684A EP0713391A4 EP 0713391 A4 EP0713391 A4 EP 0713391A4 EP 94922684 A EP94922684 A EP 94922684A EP 94922684 A EP94922684 A EP 94922684A EP 0713391 A4 EP0713391 A4 EP 0713391A4
Authority
EP
European Patent Office
Prior art keywords
inhibiting
production
human immunodeficiency
immunodeficiency viruses
azaspiranes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94922684A
Other languages
German (de)
French (fr)
Other versions
EP0713391A1 (en
Inventor
Alison Mary Badger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0713391A1 publication Critical patent/EP0713391A1/en
Publication of EP0713391A4 publication Critical patent/EP0713391A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
EP94922684A 1993-07-23 1994-07-22 Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes Withdrawn EP0713391A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9315306 1993-07-23
GB939315306A GB9315306D0 (en) 1993-07-23 1993-07-23 Methods
PCT/US1994/008275 WO1995003041A1 (en) 1993-07-23 1994-07-22 Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes

Publications (2)

Publication Number Publication Date
EP0713391A1 EP0713391A1 (en) 1996-05-29
EP0713391A4 true EP0713391A4 (en) 1998-09-09

Family

ID=10739328

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94922684A Withdrawn EP0713391A4 (en) 1993-07-23 1994-07-22 Method of inhibiting the production of human immunodeficiency viruses with substituted azaspiranes

Country Status (8)

Country Link
EP (1) EP0713391A4 (en)
CN (1) CN1130870A (en)
AU (1) AU7370894A (en)
CA (1) CA2167841A1 (en)
GB (1) GB9315306D0 (en)
NZ (1) NZ269990A (en)
WO (1) WO1995003041A1 (en)
ZA (1) ZA945416B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9315340D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315351D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
BR9601909A (en) * 1995-07-13 1999-10-13 Smithkline Beecham Corp N, n-diethyl-8,8-dipropyl-2-azaspiro (4,5) decane-2-propan amine dimaleate
CN1219129A (en) * 1996-05-17 1999-06-09 安诺梅德公司 Use of substituted azaspirane in treatment of asthma
TW574036B (en) 1998-09-11 2004-02-01 Elan Pharm Inc Stable liquid compositions of botulinum toxin

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014462A1 (en) * 1991-02-19 1992-09-03 Smithkline Beecham Corporation Cytokine inhibitors
WO1993014760A2 (en) * 1992-01-28 1993-08-05 Smithkline Beecham Corporation Methods
WO1993015735A1 (en) * 1992-01-28 1993-08-19 Smithkline Beecham Corporation (non descriptive)-a method for delaying hiv individual aids by administration of substituted azaspirane compounds
WO1995003049A1 (en) * 1993-07-23 1995-02-02 Smithkline Beecham Corporation Methods of treating hiv with azaspiranes
WO1995003042A1 (en) * 1993-07-23 1995-02-02 Smithkline Beecham Corporation Method of inhibiting the replication of human immunodeficiency viruses with substituted azaspiranes
WO1995003046A1 (en) * 1993-07-23 1995-02-02 Smithkline Beecham Corporation A method of inhibiting the production of hiv

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014462A1 (en) * 1991-02-19 1992-09-03 Smithkline Beecham Corporation Cytokine inhibitors
WO1993014760A2 (en) * 1992-01-28 1993-08-05 Smithkline Beecham Corporation Methods
WO1993015735A1 (en) * 1992-01-28 1993-08-19 Smithkline Beecham Corporation (non descriptive)-a method for delaying hiv individual aids by administration of substituted azaspirane compounds
WO1995003049A1 (en) * 1993-07-23 1995-02-02 Smithkline Beecham Corporation Methods of treating hiv with azaspiranes
WO1995003042A1 (en) * 1993-07-23 1995-02-02 Smithkline Beecham Corporation Method of inhibiting the replication of human immunodeficiency viruses with substituted azaspiranes
WO1995003046A1 (en) * 1993-07-23 1995-02-02 Smithkline Beecham Corporation A method of inhibiting the production of hiv

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BADGER A M ET AL: "ANTIARTHRITIC AND SUPPRESSOR CELL INDUCING ACTIVITY OF AZASPIRANES:STRUCTURE-FUNCTION RELATIONSHIPS OF A NOVEL CLASS OF IMMUNOMODULATORY AGENTS", JOURNAL OF MEDICINAL CHEMISTRY, vol. 33, no. 11, November 1990 (1990-11-01), pages 2963 - 2970, XP000605424 *
P.S. SARIN ET AL.: "INHIBITION OF HTLV-III REPLICATION IN CELL CULTURES", NATO ASI SER., SER. A, vol. 120, 1986, pages 329 - 342, XP002069579 *
S. GOODMAN: "THERAPEUTIC EFFECTS OF ORGANIC GERMANIUM", MEDICAL HYPOTHESES, vol. 26, 1988, pages 207 - 215, XP002069578 *
See also references of WO9503041A1 *

Also Published As

Publication number Publication date
AU7370894A (en) 1995-02-20
CA2167841A1 (en) 1995-02-02
WO1995003041A1 (en) 1995-02-02
CN1130870A (en) 1996-09-11
ZA945416B (en) 1995-05-10
EP0713391A1 (en) 1996-05-29
NZ269990A (en) 1999-07-29
GB9315306D0 (en) 1993-09-08

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