EP0708592A4 - Mts gene, mutations therein, and methods for diagnosing cancer using mts gene sequence - Google Patents

Mts gene, mutations therein, and methods for diagnosing cancer using mts gene sequence

Info

Publication number
EP0708592A4
EP0708592A4 EP95914738A EP95914738A EP0708592A4 EP 0708592 A4 EP0708592 A4 EP 0708592A4 EP 95914738 A EP95914738 A EP 95914738A EP 95914738 A EP95914738 A EP 95914738A EP 0708592 A4 EP0708592 A4 EP 0708592A4
Authority
EP
European Patent Office
Prior art keywords
mts gene
mutations
methods
diagnosing cancer
mts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95914738A
Other languages
German (de)
French (fr)
Other versions
EP0708592A1 (en
Inventor
Alexander Kamb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Myriad Genetics Inc
Original Assignee
Myriad Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myriad Genetics Inc filed Critical Myriad Genetics Inc
Publication of EP0708592A1 publication Critical patent/EP0708592A1/en
Publication of EP0708592A4 publication Critical patent/EP0708592A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP95914738A 1994-03-18 1995-03-17 Mts gene, mutations therein, and methods for diagnosing cancer using mts gene sequence Withdrawn EP0708592A4 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US21458194A 1994-03-18 1994-03-18
US21458294A 1994-03-18 1994-03-18
US21508894A 1994-03-18 1994-03-18
US214581 1994-03-18
US215088 1994-03-18
US214582 1994-03-18
US22736994A 1994-04-14 1994-04-14
US227369 1994-04-14
US25193894A 1994-06-01 1994-06-01
PCT/US1995/003316 WO1995025429A1 (en) 1994-03-18 1995-03-17 Mts gene, mutations therein, and methods for diagnosing cancer using mts gene sequence
US251938 2002-09-19

Publications (2)

Publication Number Publication Date
EP0708592A1 EP0708592A1 (en) 1996-05-01
EP0708592A4 true EP0708592A4 (en) 1997-05-07

Family

ID=27539686

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95914738A Withdrawn EP0708592A4 (en) 1994-03-18 1995-03-17 Mts gene, mutations therein, and methods for diagnosing cancer using mts gene sequence

Country Status (9)

Country Link
EP (1) EP0708592A4 (en)
JP (1) JPH08510651A (en)
CN (1) CN1128935A (en)
AU (1) AU694502B2 (en)
CA (1) CA2162147A1 (en)
FI (1) FI955415A (en)
NO (1) NO954494L (en)
NZ (1) NZ283539A (en)
WO (1) WO1995025429A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019369A1 (en) 1994-01-14 1995-07-20 Vanderbilt University Method for detection and treatment of breast cancer
US6689561B1 (en) * 1994-04-14 2004-02-10 The Regents Of The University Of California Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment
NZ313828A (en) 1995-07-17 1999-02-25 Univ Texas Expression constructs containing the encoding region of p16 and its regulatory elements and their application in cancer therapy e.g. a replication deficient adenviral vector containing p16
US7163925B1 (en) 1995-07-17 2007-01-16 Board Of Regents, The University Of Texas System p16 expression constructs and their application in cancer therapy
US6586203B1 (en) 1995-09-27 2003-07-01 St. Jude Children's Research Hospital ARF-P19, a novel regulator of the mammalian cell cycle
US5723313A (en) 1995-09-27 1998-03-03 St. Jude Children's Research Hospital ARF-p19, a novel regulator of the mammalian cell cycle
US6407062B1 (en) 1995-09-27 2002-06-18 St. Jude Children's Research Hospital ARF-P19, a novel regulator of the mammalian cell cycle
US6037121A (en) * 1995-12-08 2000-03-14 University Technologies International Inc. DNA sequence encoding a tumor suppressor gene
US6747133B1 (en) 1995-12-08 2004-06-08 University Technologies International Inc. Antibodies against the tumor suppressor gene ING1
US6117633A (en) 1995-12-08 2000-09-12 University Technologies International Inc. DNA sequence encoding the tumor suppressor gene ING1
US6143522A (en) * 1995-12-08 2000-11-07 University Technologies International, Inc. Methods of modulating apoptosis
US5672508A (en) * 1996-01-23 1997-09-30 Mitotix, Inc. Inhibitors of cell-cycle progression, and uses related thereto
US5891857A (en) * 1996-02-20 1999-04-06 Vanderbilt University Characterized BRCA1 and BRCA2 proteins and screening and therapeutic methods based on characterized BRCA1 and BRCA2 proteins
AU2383897A (en) * 1996-04-04 1997-10-29 K.U. Leuven Research & Development New member of the multiple-tumor aberrant growth gene family
US5876972A (en) * 1996-09-23 1999-03-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Nucleic acid molecules coding for tumor suppressor proteins and methods for their isolation
AU6580598A (en) * 1997-03-21 1998-10-20 Board Of Regents, The University Of Texas System (noey2) gene compositions and methods of use
US6177410B1 (en) 1997-12-05 2001-01-23 Vanderbilt University Therapeutic methods for prostate cancer
US6440706B1 (en) 1999-08-02 2002-08-27 Johns Hopkins University Digital amplification
WO2002006481A1 (en) * 2000-07-14 2002-01-24 Japan Science And Technology Corporation Target of anticancer agent
RU2484096C1 (en) * 2012-02-08 2013-06-10 Общество с ограниченной ответственностью "Технофарма" SINGLE-DOMAIN ANTIBODY aMts1 SPECIFICALLY BINDING PROTEIN S100A4/Mts1, METHOD FOR PREPARING AND USING FOR DETECTION OF THIS PROTEIN
RU2732769C1 (en) * 2020-01-10 2020-09-22 Федеральное государственное бюджетное образовательное учреждение высшего образования "Оренбургский государственный медицинский университет" Министерства здравоохранения Российской Федерации Method for prediction of high risk of recurrence in patients with ib stage of cervical cancer who received combined treatment
CN114163510A (en) * 2021-03-24 2022-03-11 深圳市新靶向生物科技有限公司 Antigenic peptide combination related to liver cancer driver gene mutation and application thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000757A1 (en) * 1990-07-09 1992-01-23 Research Corporation Technologies, Inc. Diagnosis of metastatic cancer by the mts-1 gene
WO1994009135A1 (en) * 1992-10-16 1994-04-28 Cold Spring Harbor Laboratory Cyclin complex rearrangement and uses related thereto
WO1995028483A1 (en) * 1994-04-14 1995-10-26 Cold Spring Harbor Laboratory Cell-cycle regulatory proteins, and uses related thereto
WO1995028169A1 (en) * 1994-04-14 1995-10-26 The Regents Of The University Of California Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000757A1 (en) * 1990-07-09 1992-01-23 Research Corporation Technologies, Inc. Diagnosis of metastatic cancer by the mts-1 gene
WO1994009135A1 (en) * 1992-10-16 1994-04-28 Cold Spring Harbor Laboratory Cyclin complex rearrangement and uses related thereto
WO1995028483A1 (en) * 1994-04-14 1995-10-26 Cold Spring Harbor Laboratory Cell-cycle regulatory proteins, and uses related thereto
WO1995028169A1 (en) * 1994-04-14 1995-10-26 The Regents Of The University Of California Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
HANNON GJ ET AL: "p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest [see comments]", NATURE, SEP 15 1994, 371 (6494) P257-61, ENGLAND, XP002026856 *
JEN J ET AL: "Deletion of p16 and p15 genes in brain tumors.", CANCER RES, DEC 15 1994, 54 (24) P6353-8, UNITED STATES, XP002026858 *
KAMB A ET AL: "A cell cycle regulator potentially involved in genesis of many tumor types [see comments]", SCIENCE, APR 15 1994, 264 (5157) P436-40, UNITED STATES, XP002026855 *
OKAMOTO A ET AL: "Mutations and altered expression of p16INK4 in human cancer.", PROC NATL ACAD SCI U S A, NOV 8 1994, 91 (23) P11045-9, UNITED STATES, XP002026857 *
See also references of WO9525429A1 *
SERRANO M ET AL: "A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4", NATURE, DEC 16 1993, 366 (6456) P704-7, ENGLAND, XP002026854 *

Also Published As

Publication number Publication date
AU2186395A (en) 1995-10-09
FI955415A (en) 1996-01-09
CA2162147A1 (en) 1995-09-28
AU694502B2 (en) 1998-07-23
NZ283539A (en) 1998-02-26
NO954494D0 (en) 1995-11-08
FI955415A0 (en) 1995-11-10
JPH08510651A (en) 1996-11-12
EP0708592A1 (en) 1996-05-01
CN1128935A (en) 1996-08-14
WO1995025429A1 (en) 1995-09-28
NO954494L (en) 1996-01-17

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Legal Events

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