EP0707633A4 - System for viral inactivation of blood - Google Patents

System for viral inactivation of blood

Info

Publication number
EP0707633A4
EP0707633A4 EP94921349A EP94921349A EP0707633A4 EP 0707633 A4 EP0707633 A4 EP 0707633A4 EP 94921349 A EP94921349 A EP 94921349A EP 94921349 A EP94921349 A EP 94921349A EP 0707633 A4 EP0707633 A4 EP 0707633A4
Authority
EP
European Patent Office
Prior art keywords
blood
viral inactivation
inactivation
viral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94921349A
Other languages
German (de)
French (fr)
Other versions
EP0707633A1 (en
Inventor
Henrietta Margolis-Nunno
Bernard Horowitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Blood Center Inc
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Publication of EP0707633A1 publication Critical patent/EP0707633A1/en
Publication of EP0707633A4 publication Critical patent/EP0707633A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0439—White blood cells; Leucocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/20—Pathogenic agents
    • A61M2202/206—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP94921349A 1993-06-23 1994-06-22 System for viral inactivation of blood Withdrawn EP0707633A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8177493A 1993-06-23 1993-06-23
PCT/US1994/007018 WO1995000631A1 (en) 1993-06-23 1994-06-22 System for viral inactivation of blood
US81774 2002-02-20

Publications (2)

Publication Number Publication Date
EP0707633A1 EP0707633A1 (en) 1996-04-24
EP0707633A4 true EP0707633A4 (en) 1996-08-14

Family

ID=22166309

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94921349A Withdrawn EP0707633A4 (en) 1993-06-23 1994-06-22 System for viral inactivation of blood

Country Status (9)

Country Link
EP (1) EP0707633A4 (en)
JP (1) JPH09500015A (en)
KR (1) KR960703167A (en)
AU (1) AU698154B2 (en)
CA (1) CA2165065A1 (en)
FI (1) FI956078A (en)
NO (1) NO955291L (en)
WO (1) WO1995000631A1 (en)
ZA (1) ZA944488B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319662B1 (en) 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
US5660731A (en) * 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
JP4968974B2 (en) * 1995-06-07 2012-07-04 セラス コーポレーション Method and device for removing psoralen from blood products
US6544727B1 (en) * 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
JP2009051846A (en) * 1995-06-07 2009-03-12 Cerus Corp Method and device for removing psoralen from blood product
EP1842561A1 (en) 1995-07-14 2007-10-10 CAF - DCF cvba - scrl Method and device for UV-inactivation of virus in blood products
DE19544297A1 (en) * 1995-11-28 1997-06-05 Behringwerke Ag Process for the removal of aromatic compounds from product-containing solutions
KR100455589B1 (en) * 1995-11-02 2005-02-23 쳇엘베 베링 게엠베하 How to remove aromatic compounds from biologically active proteins or peptide-containing solutions
WO1997018844A1 (en) * 1995-11-21 1997-05-29 Pall Corporation Inactivation method and system in biological fluids
US6228995B1 (en) * 1996-04-09 2001-05-08 Therakos, Inc. Method for removal of psoralens from biological fluids
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US5952235A (en) * 1997-04-14 1999-09-14 Case Western Reserve University Detection of teratogen exposure
AU747842B2 (en) 1997-11-20 2002-05-23 Cerus Corporation New psoralens for pathogen inactivation
CA2317603A1 (en) 1998-01-06 1999-07-15 Cerus Corporation Methods for quenching pathogen inactivators in biological materials
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
DE69813634T2 (en) * 1998-07-16 2004-01-22 Shanbrom Technologies, LLC, Ojai REMOVAL OF DISINFECTANT COLORS
FR2797403B1 (en) * 1999-08-09 2002-03-15 Maco Pharma Sa TRANSFUSION LINE WITH MEANS FOR FILTERING A COLORED SUBSTANCE
KR100404235B1 (en) * 2000-09-19 2003-11-01 (주)바이오니아 Multi-layer filter for purification of nucleic acid
FR2817152B1 (en) * 2000-11-29 2003-05-09 Maco Pharma Sa POCKET SYSTEM AND METHOD FOR VIRAL INACTIVATION OF A PRE-DELEUCOCYTE FLUID
AU2002359918A1 (en) * 2001-12-28 2003-07-24 Terumo Kabushiki Kaisha Blood bag system and method of inactivating pathogenic microorganisms
AU2005302256B2 (en) 2004-10-29 2011-01-20 Cerus Corporation Improved quenching methods for red blood cell inactivation process
DE102006014184A1 (en) * 2006-03-24 2007-09-27 Heim, Heidrun Deactivating unwanted organisms in blood plasma, especially viruses, involves adding porphyrin to blood plasma immediately after extracting it from blood and irradiating mixture with xenon radiation
DE102007002291A1 (en) * 2007-01-16 2008-07-17 Fresenius Hemocare Deutschland Gmbh Apparatus and method for filtering a mixture of a blood component and an additive solution
CN102046006B (en) 2008-04-09 2014-09-24 塞鲁斯公司 Improved quenching methods for red blood cell pathogen inactivation
ES2895173T3 (en) 2012-06-29 2022-02-17 Emd Millipore Corp Methods to inactivate viruses during a protein purification process
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
US9782707B2 (en) 2014-03-24 2017-10-10 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US10376627B2 (en) 2014-03-24 2019-08-13 Fenwal, Inc. Flexible biological fluid filters
US9796166B2 (en) 2014-03-24 2017-10-24 Fenwal, Inc. Flexible biological fluid filters
US9968738B2 (en) 2014-03-24 2018-05-15 Fenwal, Inc. Biological fluid filters with molded frame and methods for making such filters
US10159778B2 (en) 2014-03-24 2018-12-25 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
DK3131589T3 (en) * 2014-04-15 2023-08-07 Boehringer Ingelheim Int METHOD AND USE FOR CONTINUOUS INACTIVATION OF A VIRUS WHILE PROVIDING A BIOLOGICAL PRODUCT

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003933A1 (en) * 1989-09-13 1991-04-04 Blutspendedienst Der Landesverbände Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. Process for inactivating viruses in blood and blood products

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US5176921A (en) * 1983-05-02 1993-01-05 Diamond Scientific Co. Method of blood component decontamination by glucose addition
US4748120A (en) * 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
US4855064A (en) * 1988-01-13 1989-08-08 Viratec, Inc. Apparatus and method for decontaminating virus-infected body fluids
US5049460A (en) * 1988-05-31 1991-09-17 Siemens Aktiengesellschaft Method for producing beam-shaping diaphragms for lithographic devices
EP0349188B1 (en) * 1988-06-23 1992-09-02 ASAHI MEDICAL Co., Ltd. Method for separating blood into blood components, and blood components separator unit
US5094960A (en) * 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5240829A (en) * 1989-02-10 1993-08-31 Miles Inc. Method for inactivating viruses in blood using chlorine dioxide
US5128048A (en) * 1991-05-22 1992-07-07 Baxter International Inc. Systems and methods for removing undesired matter from blood cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003933A1 (en) * 1989-09-13 1991-04-04 Blutspendedienst Der Landesverbände Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen G.G.M.B.H. Process for inactivating viruses in blood and blood products

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HANNU SUOMELA: "INACTIVATION OF VIRUSES IN BLOOD AND PLASMA PRODUCTS", TRANSFUSION MEDICINE REVIEWS, vol. VII, no. 1, January 1993 (1993-01-01), pages 42 - 57, XP000573510 *
J.L. MATTHEWS ET AL.: "PRELIMINARY STUDIES OF PHOTOINACTIVATION OF HUMAN IMMUNODEFICIENCY VIRUS IN BLOOD", TRANSFUSION, vol. 31, no. 7, 1991, US, pages 636 - 641, XP000573464 *
L.I. FRIEDMAN ET AL.: "VIRAL INACTIVATION AND REDUCTION IN CELLULAR BLOOD PRODUCTS", REVUE FRANCAISE DE TRANSFUSION ET D'HEMOBIOLOGIE, vol. 36, no. 1, January 1993 (1993-01-01), pages 83 - 91, XP000573121 *
T. BURNOUF ET AL.: "L'INACTIVATION DES VIRUS DANS LES FRACTIONS PLASMATIQUES A USAGE THERAPEUTIQUE", NOUVELLE REVUE FRANCAISE D'HEMATOLOGIE, vol. 29, no. 1, 1987, pages 93 - 96, XP000573465 *

Also Published As

Publication number Publication date
NO955291D0 (en) 1995-12-22
KR960703167A (en) 1996-06-19
EP0707633A1 (en) 1996-04-24
AU698154B2 (en) 1998-10-22
NO955291L (en) 1996-02-22
WO1995000631A1 (en) 1995-01-05
JPH09500015A (en) 1997-01-07
CA2165065A1 (en) 1995-01-05
ZA944488B (en) 1995-02-15
FI956078A (en) 1996-02-14
AU7211394A (en) 1995-01-17
FI956078A0 (en) 1995-12-18

Similar Documents

Publication Publication Date Title
ZA944488B (en) System for viral inactivation of blood
EP0720835A3 (en) Surgical system
GB9206018D0 (en) Bone fixation system
AU7232094A (en) Bone fixation system
KR970011383B1 (en) Spinal fixation system
AU5750796A (en) System for the treatment of insomnia
ZA936865B (en) Osteosynthesis aid
ZA954436B (en) Process of sterilization
AU6267596A (en) Inactivation of non-enveloped virus
ZA896450B (en) Viral treatment system
IL93094A0 (en) Blood purification system
GB9304746D0 (en) Treatment of viral infections
SG42309A1 (en) Medical use of enzymes
AU2000792A (en) Knee-cap for treatment of injured joint
AU3893495A (en) Solution sterilization system and method of operation
AU4307493A (en) Osteosynthetic auxiliary for the fixation of bones
AU3530395A (en) Treatment of viral infections
IL130160A0 (en) Inactivation of HIV co-receptors as therapy for HIV infection
EP0655919A4 (en) Treatment of human viral infections.
AU3638895A (en) Heat treatment for viral inactivation
GB9216360D0 (en) Treatment of blood
EP0412938A3 (en) System for the treatment of contactlenses
AU3787393A (en) Viral inactivation method
GB9206226D0 (en) Blood treatment system
ZA941471B (en) Treatment of viral infections

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19951215

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19960701

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 19981210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19990622