EP0683675A4 - Human monoclonal antibodies to cytomegalovirus. - Google Patents

Human monoclonal antibodies to cytomegalovirus.

Info

Publication number
EP0683675A4
EP0683675A4 EP94908670A EP94908670A EP0683675A4 EP 0683675 A4 EP0683675 A4 EP 0683675A4 EP 94908670 A EP94908670 A EP 94908670A EP 94908670 A EP94908670 A EP 94908670A EP 0683675 A4 EP0683675 A4 EP 0683675A4
Authority
EP
European Patent Office
Prior art keywords
cytomegalovirus
monoclonal antibodies
human monoclonal
human
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94908670A
Other languages
German (de)
French (fr)
Other versions
EP0683675A1 (en
Inventor
Lars G Ostberg
Paul Nadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharmaceuticals Corp
Original Assignee
Sandoz Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Pharmaceuticals Corp filed Critical Sandoz Pharmaceuticals Corp
Publication of EP0683675A1 publication Critical patent/EP0683675A1/en
Publication of EP0683675A4 publication Critical patent/EP0683675A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/089—Cytomegalovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP94908670A 1993-01-28 1994-01-28 Human monoclonal antibodies to cytomegalovirus. Withdrawn EP0683675A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1022893A 1993-01-28 1993-01-28
US7380893A 1993-06-09 1993-06-09
PCT/US1994/001068 WO1994016730A1 (en) 1993-01-28 1994-01-28 Human monoclonal antibodies to cytomegalovirus
US10228 1996-01-19
US73808 2008-06-19

Publications (2)

Publication Number Publication Date
EP0683675A1 EP0683675A1 (en) 1995-11-29
EP0683675A4 true EP0683675A4 (en) 1997-05-21

Family

ID=26680936

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94908670A Withdrawn EP0683675A4 (en) 1993-01-28 1994-01-28 Human monoclonal antibodies to cytomegalovirus.

Country Status (5)

Country Link
EP (1) EP0683675A4 (en)
JP (1) JPH08506325A (en)
AU (1) AU695584B2 (en)
CA (1) CA2153790A1 (en)
WO (1) WO1994016730A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus
WO2001082965A1 (en) * 2000-05-03 2001-11-08 Medimmune, Inc. Combination therapy of respiratory diseases using antibodies
JPWO2007094423A1 (en) * 2006-02-15 2009-07-09 株式会社イーベック Human monoclonal antibody binding to human cytomegalovirus and antigen-binding portion thereof
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US8202518B2 (en) 2007-07-04 2012-06-19 Ribovax Biotechnologies S.A. Antibodies against human cytomegalovirus (HCMV)
WO2009155535A2 (en) 2008-06-20 2009-12-23 Duke University Compositions, methods and kits for eliciting an immune response
PT3009449T (en) 2008-07-16 2018-09-28 Inst Res Biomedicine Human cytomegalovirus neutralizing antibodies and use thereof
ES2539751T3 (en) 2009-04-01 2015-07-03 Evec Incorporated Monoclonal antibody capable of binding with specific discontinuous epitope that appears in the AD1 region of the human cytomegalovirus gB glycoprotein, and antigen-binding fragment thereof
AU2011312425A1 (en) * 2010-09-29 2013-04-11 Genentech, Inc. Antibody compositions and methods of use
CN111741976A (en) 2017-12-19 2020-10-02 F星贝塔有限公司 FC-binding fragments comprising the PD-L1 antigen-binding site
BR112021000394A2 (en) 2018-07-12 2021-04-06 F-Star Beta Limited ANTIBODY MOLECULES THAT BIND TO PD-L1 AND CD137

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DUMMER: "CYTOMEGALOVIRUS INFECTION AFTER LIVER TRANSPLANTATION: CLINICAL MANIFESTATIONS AND STRATEGIES FOR PREVENTION", REVIEWS OF INFECTIOUS DISEASES, vol. 12, no. S7, 1990, pages S767 - S775, XP000647578 *
NOKTA ET AL: "HUMAN MONOCLONAL ANTI CYTOMEGALOVIRUS (CMV) ANTIBODY (MSL-109): ENHANCEMENT OF IN VITRO FOSCARNET INDUCED INHIBITION OF CMV REPLICATION", ANTIVIRAL RESEARCH, vol. 17, no. S1, 1992, pages 97, XP002027786 *
See also references of WO9416730A1 *
STRATTA ET AL: "CYTOMEGALOVIRUS INFECTION AND DISEASE AFTER LIVER TRANSPLANTATION. AN OVERVIEW", DIGESTIVE DISEASES AND SCIENCES, vol. 37, 1992, pages 673 - 688, XP000647567 *

Also Published As

Publication number Publication date
EP0683675A1 (en) 1995-11-29
CA2153790A1 (en) 1994-08-04
AU6167794A (en) 1994-08-15
JPH08506325A (en) 1996-07-09
WO1994016730A1 (en) 1994-08-04
AU695584B2 (en) 1998-08-20

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