EP0675718A4 - Substituted pyridyl compounds useful as leukotriene antagonists. - Google Patents

Substituted pyridyl compounds useful as leukotriene antagonists.

Info

Publication number
EP0675718A4
EP0675718A4 EP19940904523 EP94904523A EP0675718A4 EP 0675718 A4 EP0675718 A4 EP 0675718A4 EP 19940904523 EP19940904523 EP 19940904523 EP 94904523 A EP94904523 A EP 94904523A EP 0675718 A4 EP0675718 A4 EP 0675718A4
Authority
EP
European Patent Office
Prior art keywords
compounds useful
substituted pyridyl
leukotriene antagonists
pyridyl compounds
leukotriene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19940904523
Other languages
German (de)
French (fr)
Other versions
EP0675718A1 (en
Inventor
Robert A Daines
Israil Pendrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0675718A4 publication Critical patent/EP0675718A4/en
Publication of EP0675718A1 publication Critical patent/EP0675718A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP94904523A 1992-12-23 1993-12-21 Substituted pyridyl compounds useful as leukotriene antagonists Withdrawn EP0675718A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99621992A 1992-12-23 1992-12-23
US996219 1992-12-23
PCT/US1993/012518 WO1994014442A1 (en) 1992-12-23 1993-12-21 Substituted pyridyl compounds useful as leukotriene antagonists

Publications (2)

Publication Number Publication Date
EP0675718A4 true EP0675718A4 (en) 1995-08-22
EP0675718A1 EP0675718A1 (en) 1995-10-11

Family

ID=25542633

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94904523A Withdrawn EP0675718A1 (en) 1992-12-23 1993-12-21 Substituted pyridyl compounds useful as leukotriene antagonists

Country Status (3)

Country Link
EP (1) EP0675718A1 (en)
JP (1) JPH08505148A (en)
WO (1) WO1994014442A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018880A1 (en) * 1990-06-07 1991-12-12 Smithkline Beecham Corporation Benzoic acid derivatives for treating leukotriene-related diseases
WO1993010780A1 (en) * 1991-12-06 1993-06-10 Smithkline Beecham Corporation Heterocyclic-substituted pyridine compounds and uses
WO1993011768A1 (en) * 1991-12-13 1993-06-24 Smithkline Beecham Corporation Pyridyl compounds for psoriasis treatment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018880A1 (en) * 1990-06-07 1991-12-12 Smithkline Beecham Corporation Benzoic acid derivatives for treating leukotriene-related diseases
WO1993010780A1 (en) * 1991-12-06 1993-06-10 Smithkline Beecham Corporation Heterocyclic-substituted pyridine compounds and uses
WO1993011768A1 (en) * 1991-12-13 1993-06-24 Smithkline Beecham Corporation Pyridyl compounds for psoriasis treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9414442A1 *

Also Published As

Publication number Publication date
WO1994014442A1 (en) 1994-07-07
JPH08505148A (en) 1996-06-04
EP0675718A1 (en) 1995-10-11

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