EP0674658A4 - A novel protein tyrosine kinase. - Google Patents

A novel protein tyrosine kinase.

Info

Publication number
EP0674658A4
EP0674658A4 EP93923978A EP93923978A EP0674658A4 EP 0674658 A4 EP0674658 A4 EP 0674658A4 EP 93923978 A EP93923978 A EP 93923978A EP 93923978 A EP93923978 A EP 93923978A EP 0674658 A4 EP0674658 A4 EP 0674658A4
Authority
EP
European Patent Office
Prior art keywords
tyrosine kinase
protein tyrosine
novel protein
novel
kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93923978A
Other languages
German (de)
French (fr)
Other versions
EP0674658A1 (en
Inventor
Andrew Frederick Wilks
Andrew Stewart Runting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
Original Assignee
Ludwig Institute for Cancer Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Institute for Cancer Research Ltd filed Critical Ludwig Institute for Cancer Research Ltd
Publication of EP0674658A1 publication Critical patent/EP0674658A1/en
Publication of EP0674658A4 publication Critical patent/EP0674658A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP93923978A 1992-10-30 1993-10-29 A novel protein tyrosine kinase. Withdrawn EP0674658A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPL5581/92 1992-10-30
AUPL558192 1992-10-30
PCT/AU1993/000560 WO1994010197A1 (en) 1992-10-30 1993-10-29 A novel protein tyrosine kinase

Publications (2)

Publication Number Publication Date
EP0674658A1 EP0674658A1 (en) 1995-10-04
EP0674658A4 true EP0674658A4 (en) 1997-12-03

Family

ID=3776507

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93923978A Withdrawn EP0674658A4 (en) 1992-10-30 1993-10-29 A novel protein tyrosine kinase.

Country Status (3)

Country Link
EP (1) EP0674658A4 (en)
JP (1) JPH08504760A (en)
WO (1) WO1994010197A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585269A (en) * 1994-06-02 1996-12-17 The University Of North Carolina At Chapel Hill Isolated DNA encoding c-mer protooncogene
GB9517098D0 (en) * 1995-08-21 1995-10-25 Imperial College Receptor
US6521424B2 (en) 1999-06-07 2003-02-18 Immunex Corporation Recombinant expression of Tek antagonists
US7485297B2 (en) 2003-08-12 2009-02-03 Dyax Corp. Method of inhibition of vascular development using an antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004694A1 (en) * 1992-08-25 1994-03-03 Mount Sinai Hospital Corporation Endothelial lineage specific transcriptional regulatory element from tek

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR940703857A (en) * 1992-01-09 1994-12-12 티모 에스코 Tie, A NOVEL ENDOTHELIAL CELL RECEPTOR TYROSINE KINASE

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004694A1 (en) * 1992-08-25 1994-03-03 Mount Sinai Hospital Corporation Endothelial lineage specific transcriptional regulatory element from tek

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
IWAMA A ET AL: "MOLECULAR CLONING AND CHARACTERIZATION OF MOUSE TIE AND TEK RECEPTOR TYROSINE KINASE GENES AND THEIR EXPRESSION IN HEMATOPOIETIC STEM CELLS.", BIOCHEM BIOPHYS RES COMMUN 195 (1). 1993. 301-309. CODEN: BBRCA9 ISSN: 0006-291X, XP002042960 *
J. PARTANEN ET AL.: "A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains", MOLECULAR AND CELLULAR BIOLOGY, vol. 12, no. 4, April 1992 (1992-04-01), pages 1698 - 1707, XP002042962 *
See also references of WO9410197A1 *
T.N. SATO ET AL.: "tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system.", PROC. NATL. ACAD. SCI. USA, vol. 90, October 1993 (1993-10-01), pages 9355 - 9358, XP002042961 *

Also Published As

Publication number Publication date
WO1994010197A1 (en) 1994-05-11
JPH08504760A (en) 1996-05-21
EP0674658A1 (en) 1995-10-04

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Legal Events

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Effective date: 19991029