EP0666745A4 - Diagnosis and therapy for parkinson's disease. - Google Patents
Diagnosis and therapy for parkinson's disease.Info
- Publication number
- EP0666745A4 EP0666745A4 EP92918207A EP92918207A EP0666745A4 EP 0666745 A4 EP0666745 A4 EP 0666745A4 EP 92918207 A EP92918207 A EP 92918207A EP 92918207 A EP92918207 A EP 92918207A EP 0666745 A4 EP0666745 A4 EP 0666745A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- parkinson
- diagnosis
- therapy
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12Y104/03004—Monoamine oxidase (1.4.3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76230291A | 1991-09-20 | 1991-09-20 | |
US762302 | 1991-09-20 | ||
PCT/US1992/006746 WO1993005783A1 (en) | 1991-09-20 | 1992-08-17 | Diagnosis and therapy for parkinson's disease |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0666745A1 EP0666745A1 (en) | 1995-08-16 |
EP0666745A4 true EP0666745A4 (en) | 1995-10-25 |
Family
ID=25064666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP92918207A Withdrawn EP0666745A4 (en) | 1991-09-20 | 1992-08-17 | Diagnosis and therapy for parkinson's disease. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0666745A4 (en) |
JP (1) | JPH07501518A (en) |
AU (1) | AU2492192A (en) |
CA (1) | CA2116130A1 (en) |
WO (1) | WO1993005783A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5783680A (en) * | 1993-10-06 | 1998-07-21 | The General Hospital Corporation | Genetic diagnosis and treatment for impulsive aggression |
WO2002010454A2 (en) * | 2000-07-28 | 2002-02-07 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the alas2 gene |
WO2002012561A2 (en) * | 2000-08-03 | 2002-02-14 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the or1g1 gene |
AU2001294513A1 (en) * | 2000-08-04 | 2002-02-18 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the ntf3 gene |
AU2001284732A1 (en) * | 2000-08-04 | 2002-02-18 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the edg4 gene |
AU2001281123A1 (en) * | 2000-08-04 | 2002-02-18 | Genaissance Pharmaceuticals, Inc. | Haplotypes of the isl1 gene |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990000195A1 (en) * | 1988-06-30 | 1990-01-11 | Xandra Breakefield | Dna encoding human monoamine oxidase type a |
WO1991018005A1 (en) * | 1990-05-14 | 1991-11-28 | Duke University | Cloned genes encoding the d1 dopamine receptor |
-
1992
- 1992-08-17 CA CA002116130A patent/CA2116130A1/en not_active Abandoned
- 1992-08-17 JP JP5506029A patent/JPH07501518A/en active Pending
- 1992-08-17 EP EP92918207A patent/EP0666745A4/en not_active Withdrawn
- 1992-08-17 WO PCT/US1992/006746 patent/WO1993005783A1/en not_active Application Discontinuation
- 1992-08-17 AU AU24921/92A patent/AU2492192A/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990000195A1 (en) * | 1988-06-30 | 1990-01-11 | Xandra Breakefield | Dna encoding human monoamine oxidase type a |
WO1991018005A1 (en) * | 1990-05-14 | 1991-11-28 | Duke University | Cloned genes encoding the d1 dopamine receptor |
Non-Patent Citations (6)
Title |
---|
DATABASE WPI Week 5091, Derwent World Patents Index; AN 91-369177 * |
G.C.M. BLACK ET AL.: "Dinucleotide repeat polymorphism at the MAOA locus", NUCLEIC ACIDS RESEARCH, vol. 19, no. 3, 11 February 1991 (1991-02-11), IRL PRESS LIMITED,OXFORD,ENGLAND, pages 689 * |
G.S. HOTAMISLIGIL AND X.O. BREAKEFIELD: "Human monoamine oxidase A gene determines level of enzyme activity", AM.J. HUMAN. GENET., vol. 49, no. 2, AM.SOC.HUM.GENET.,CHICAGO,US, pages 383 - 392 * |
G.S. HOTAMITLISGIL ET AL.: "Allelic variation in MAO genes mark activity states and may predict vulnerability to Parkinson disease", AM.J. HUMAN. GENET. SUPPLEMENT, vol. 49, no. 4, AM.SOC.HUM.GENET.,CHICAGO,US, pages 407 * |
See also references of WO9305783A1 * |
Z.-Y. CHEN ET AL.: "Structure of the human gene for monoamine oxidase type A", NUCLEIC ACIDS RESEARCH, vol. 19, no. 16, 25 August 1991 (1991-08-25), IRL PRESS LIMITED,OXFORD,ENGLAND, pages 4537 - 4541 * |
Also Published As
Publication number | Publication date |
---|---|
WO1993005783A1 (en) | 1993-04-01 |
JPH07501518A (en) | 1995-02-16 |
AU2492192A (en) | 1993-04-27 |
CA2116130A1 (en) | 1993-04-01 |
EP0666745A1 (en) | 1995-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19940414 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE |
|
RHK1 | Main classification (correction) |
Ipc: C12N 15/53 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19950912 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19960217 |