EP0656784A4 - Parathyroid hormone fragments and analogs. - Google Patents

Parathyroid hormone fragments and analogs.

Info

Publication number
EP0656784A4
EP0656784A4 EP93919895A EP93919895A EP0656784A4 EP 0656784 A4 EP0656784 A4 EP 0656784A4 EP 93919895 A EP93919895 A EP 93919895A EP 93919895 A EP93919895 A EP 93919895A EP 0656784 A4 EP0656784 A4 EP 0656784A4
Authority
EP
European Patent Office
Prior art keywords
analogs
parathyroid hormone
hormone fragments
fragments
parathyroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93919895A
Other languages
German (de)
French (fr)
Other versions
EP0656784A1 (en
Inventor
Sandra R Hilliker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0656784A1 publication Critical patent/EP0656784A1/en
Publication of EP0656784A4 publication Critical patent/EP0656784A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP93919895A 1992-08-05 1993-08-05 Parathyroid hormone fragments and analogs. Withdrawn EP0656784A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92607092A 1992-08-05 1992-08-05
US926070 1992-08-05
PCT/US1993/007375 WO1994003201A1 (en) 1992-08-05 1993-08-05 Parathyroid hormone fragments and analogs

Publications (2)

Publication Number Publication Date
EP0656784A1 EP0656784A1 (en) 1995-06-14
EP0656784A4 true EP0656784A4 (en) 1997-06-04

Family

ID=25452700

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93919895A Withdrawn EP0656784A4 (en) 1992-08-05 1993-08-05 Parathyroid hormone fragments and analogs.

Country Status (4)

Country Link
EP (1) EP0656784A4 (en)
JP (1) JPH08503692A (en)
CA (1) CA2141588A1 (en)
WO (1) WO1994003201A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814603A (en) * 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
DE4434551A1 (en) * 1994-09-28 1996-04-04 Forssmann Wolf Georg Prof Dr D Peptides from the sequence of hPTH (1-37)
AUPP794898A0 (en) * 1998-12-24 1999-01-28 Garvan Institute Of Medical Research Transgenic animal
US7820393B2 (en) 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US6923968B2 (en) 2000-08-10 2005-08-02 Scantibodies Laboratory, Inc. Cyclase inhibiting parathyroid hormone antagonists or modulators and osteoporosis
WO2004028444A2 (en) 1999-06-02 2004-04-08 Scantibodies Laboratory, Inc. Parathyroid hormone antagonists and uses thereof
US6524788B1 (en) 2001-11-02 2003-02-25 Thomas L. Cantor Methods for monitoring and guiding therapeutic suppression of parathyroid hormone in renal patients having secondary hyperparathyroidism
US7056655B2 (en) 2001-11-02 2006-06-06 Scantibodies Laboratory, Inc. Methods for monitoring and guiding therapeutic suppression of parathyroid hormone in renal patients having secondary hyperparathyroidism
EP1531855A4 (en) 2002-01-10 2009-07-22 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
JP2009515535A (en) 2005-11-10 2009-04-16 ボード オブ コントロール オブ ミシガン テクノロジカル ユニヴァーシティー Methods of using black bear parathyroid hormone and black bear parathyroid hormone
EP2509996A1 (en) 2009-12-07 2012-10-17 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015109A2 (en) * 1992-02-04 1993-08-05 Boehringer Mannheim Gmbh Parathyroid hormone fragments, their preparation and medicaments containing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) * 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US4968669A (en) * 1988-05-09 1990-11-06 Merck & Co., Inc. Parathyroid hormone antagonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015109A2 (en) * 1992-02-04 1993-08-05 Boehringer Mannheim Gmbh Parathyroid hormone fragments, their preparation and medicaments containing the same

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 97, no. 1, 1982, Columbus, Ohio, US; abstract no. 9739388k, CASARETTO MONIKA ET AL.: "Synthesis of two median segments of human parathyrin" page 622; XP002025230 *
FUNAKOSHI, SUSUMU ET AL.: "Studies on peptides. CIX. Synthesis of the Octratricontapeptide corresponding to Positions 1 to 38 of Human Parathyroid Hormone", CHEM. PHARM. BULL., vol. 30, no. 5, 1982, pages 1706 - 17, XP000615407 *
FUNAKOSHI, SUSUMU ET AL.: "Studies on Peptides. CVIII. Synthesis of the Protected Eicosapeptide corresponding to positions 19 to 38 of Human Parathyroid Hormone", CHEM.PHARM. BULL.,, vol. 30, no. 5, 1982, pages 1697 - 705, XP000615406 *
HOPPE-SEYLER'S Z.PHYSIOL.CHEM., vol. 363, no. 4, 1982, pages 407 - 23 *
KIMURA, TERUTHOSHI ET AL.: "Total Synthesis of Human Parathyroid Hormone 1-84)", PEPT. CHEM., vol. 19th, 1981 - 1982, pages 131 - 6, XP000613382 *
See also references of WO9403201A1 *

Also Published As

Publication number Publication date
JPH08503692A (en) 1996-04-23
CA2141588A1 (en) 1994-02-17
WO1994003201A1 (en) 1994-02-17
EP0656784A1 (en) 1995-06-14

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950215

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

RHK1 Main classification (correction)

Ipc: A61K 38/00

RHK1 Main classification (correction)

Ipc: C07K 5/00

A4 Supplementary search report drawn up and despatched

Effective date: 19970423

AK Designated contracting states

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Effective date: 19971107

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19980318