EP0641354A4 - Oligonucleotides having aminohydrocarbon phosphonate moieties. - Google Patents

Oligonucleotides having aminohydrocarbon phosphonate moieties.

Info

Publication number
EP0641354A4
EP0641354A4 EP92925362A EP92925362A EP0641354A4 EP 0641354 A4 EP0641354 A4 EP 0641354A4 EP 92925362 A EP92925362 A EP 92925362A EP 92925362 A EP92925362 A EP 92925362A EP 0641354 A4 EP0641354 A4 EP 0641354A4
Authority
EP
European Patent Office
Prior art keywords
aminohydrocarbon
oligonucleotides
phosphonate moieties
phosphonate
moieties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92925362A
Other languages
German (de)
French (fr)
Other versions
EP0641354A1 (en
Inventor
Alan F Cook
Reza Fathi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmagenics Inc
Original Assignee
Pharmagenics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmagenics Inc filed Critical Pharmagenics Inc
Publication of EP0641354A1 publication Critical patent/EP0641354A1/en
Publication of EP0641354A4 publication Critical patent/EP0641354A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
EP92925362A 1991-11-25 1992-11-20 Oligonucleotides having aminohydrocarbon phosphonate moieties. Withdrawn EP0641354A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79680491A 1991-11-25 1991-11-25
US796804 1991-11-25
PCT/US1992/010043 WO1993011148A1 (en) 1991-11-25 1992-11-20 Oligonucleotides having aminohydrocarbon phosphonate moieties

Publications (2)

Publication Number Publication Date
EP0641354A1 EP0641354A1 (en) 1995-03-08
EP0641354A4 true EP0641354A4 (en) 1996-01-10

Family

ID=25169100

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92925362A Withdrawn EP0641354A4 (en) 1991-11-25 1992-11-20 Oligonucleotides having aminohydrocarbon phosphonate moieties.

Country Status (5)

Country Link
EP (1) EP0641354A4 (en)
JP (1) JPH07501542A (en)
AU (1) AU3144593A (en)
CA (1) CA2122470A1 (en)
WO (1) WO1993011148A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017700A (en) * 1995-08-04 2000-01-25 Bayer Corporation Cationic oligonucleotides, and related methods of synthesis and use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4471113A (en) * 1982-02-03 1984-09-11 The United States Of America As Represented By The Department Of Energy Prodrugs based on phospholipid-nucleoside conjugates

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9311148A1 *

Also Published As

Publication number Publication date
CA2122470A1 (en) 1993-06-10
EP0641354A1 (en) 1995-03-08
JPH07501542A (en) 1995-02-16
AU3144593A (en) 1993-06-28
WO1993011148A1 (en) 1993-06-10

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