EP0635058A4 - Protease vaccine against heartworm. - Google Patents

Protease vaccine against heartworm.

Info

Publication number
EP0635058A4
EP0635058A4 EP19920924400 EP92924400A EP0635058A4 EP 0635058 A4 EP0635058 A4 EP 0635058A4 EP 19920924400 EP19920924400 EP 19920924400 EP 92924400 A EP92924400 A EP 92924400A EP 0635058 A4 EP0635058 A4 EP 0635058A4
Authority
EP
European Patent Office
Prior art keywords
vaccine against
protease vaccine
against heartworm
heartworm
protease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19920924400
Other languages
German (de)
French (fr)
Other versions
EP0635058A1 (en
Inventor
Robert B Grieve
Jennifer Richer
Glenn R Frank
Judy Sakanari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Colorado State University Research Foundation
Colorado State University
Original Assignee
Colorado State University Research Foundation
Colorado State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colorado State University Research Foundation, Colorado State University filed Critical Colorado State University Research Foundation
Publication of EP0635058A4 publication Critical patent/EP0635058A4/en
Publication of EP0635058A1 publication Critical patent/EP0635058A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
    • G01N2333/4353—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP92924400A 1991-11-12 1992-11-12 Protease vaccine against heartworm Withdrawn EP0635058A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79220991A 1991-11-12 1991-11-12
US792209 1991-11-12
PCT/US1992/009702 WO1993010225A1 (en) 1991-11-12 1992-11-12 Protease vaccine against heartworm

Publications (2)

Publication Number Publication Date
EP0635058A4 true EP0635058A4 (en) 1994-12-07
EP0635058A1 EP0635058A1 (en) 1995-01-25

Family

ID=25156129

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92924400A Withdrawn EP0635058A1 (en) 1991-11-12 1992-11-12 Protease vaccine against heartworm

Country Status (5)

Country Link
EP (1) EP0635058A1 (en)
JP (1) JPH07501219A (en)
AU (1) AU675214B2 (en)
CA (1) CA2123420A1 (en)
WO (1) WO1993010225A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639876A (en) * 1991-02-12 1997-06-17 Heska Corporation Nucleic acid molecules encoding novel parasitic helminth proteins
US5795768A (en) * 1991-02-12 1998-08-18 Heska Corporation Filariid nematode cysteine protease proteins, nucleic acid molecules and uses thereof
US5492695A (en) * 1992-05-14 1996-02-20 Colorado State University Research Foundation Vaccinating cats against Dirofilaria immitis with an L4 homogenate
CA2147378A1 (en) * 1992-10-21 1994-04-28 John P. Dalton Vaccine containing a thiol protease
GB9403819D0 (en) * 1994-02-28 1994-04-20 Univ Leeds Control of parasites
AU726774B2 (en) * 1994-05-26 2000-11-23 Heska Corporation Novel parasite protease genes and proteins
US6265198B1 (en) 1994-05-26 2001-07-24 Heska Corporation Parasite astacin metalloendopeptidase proteins
US6281345B1 (en) 1994-05-26 2001-08-28 Heska Corporation Parasite astacin metalloendopeptidase nucleic acid molecules and uses thereof
WO1995032988A1 (en) * 1994-05-26 1995-12-07 Heska Corporation Novel parasite protease genes and proteins
DE19543554A1 (en) * 1995-11-22 1997-05-28 Bayer Ag Identification of antigens from post-infectious nematodes for the development of new anthelmintics and vaccines
FR2750865B1 (en) * 1996-06-27 1998-12-04 Rhone Merieux RECOMBINANT LIVING VACCINE BASED ON CANINE HERPESVIRUS, IN PARTICULAR FOR SQUARE DISEASE, RABIES OR TYPE 2 PARAINFLUENZA VIRUS
BR0009944A (en) * 1999-04-21 2002-01-08 Univ Georgia Res Foudation Inc Cysteine protease and inhibitors for the prevention and treatment of neurocysticercosis
US7416854B2 (en) * 2004-01-22 2008-08-26 Promega Corporation Luminogenic and nonluminogenic multiplex assay
WO2017176950A2 (en) 2016-04-07 2017-10-12 Merial, Inc. Heartworm vaccine, methods and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006467A1 (en) * 1986-04-22 1987-11-05 Immunomed Corporation Vaccine
US4842999A (en) * 1986-08-11 1989-06-27 Adi Diagnostics Inc. Canine heartworm vaccine and diagnostic test
EP0434909A2 (en) * 1989-09-18 1991-07-03 Synergen, Inc. Anticoagulant and antihelminthic proteins and methods for the production and use of same
WO1992013560A1 (en) * 1991-02-12 1992-08-20 Colorado State University Research Foundation Reagents and methods for identification of vaccines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006467A1 (en) * 1986-04-22 1987-11-05 Immunomed Corporation Vaccine
US4842999A (en) * 1986-08-11 1989-06-27 Adi Diagnostics Inc. Canine heartworm vaccine and diagnostic test
EP0434909A2 (en) * 1989-09-18 1991-07-03 Synergen, Inc. Anticoagulant and antihelminthic proteins and methods for the production and use of same
WO1992013560A1 (en) * 1991-02-12 1992-08-20 Colorado State University Research Foundation Reagents and methods for identification of vaccines

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 104, no. 23, 9 June 1986, Columbus, Ohio, US; abstract no. 204191, I. PETRALANDA: "Studies on a filarial antigen with collagenase activity" page 471; *
J. RICHER ET AL: "Dirofilaria immitis: proteases produced by third- and fourth - stage larvae", EXP. PARASITOLOGY, vol. 75, no. 2, 2 September 1992 (1992-09-02), pages 213 - 222, XP026225098, DOI: doi:10.1016/0014-4894(92)90181-9 *
MOL BIOCHEM. PARASITOL, vol. 19, no. 1, 1986, pages 51 - 59 *
R. MAIZELS ET AL: "Prospects for new vaccines against helminth parasites", TRENDS IN BIOTECHNOLOGY., vol. 7, no. 11, November 1989 (1989-11-01), CAMBRIDGE GB, pages 316 - 321, XP023595439, DOI: doi:10.1016/0167-7799(89)90114-5 *
See also references of WO9310225A1 *

Also Published As

Publication number Publication date
WO1993010225A1 (en) 1993-05-27
EP0635058A1 (en) 1995-01-25
AU3072392A (en) 1993-06-15
JPH07501219A (en) 1995-02-09
AU675214B2 (en) 1997-01-30
CA2123420A1 (en) 1993-05-27

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