EP0589958A4 - Universal site-specific nucleases. - Google Patents

Universal site-specific nucleases.

Info

Publication number
EP0589958A4
EP0589958A4 EP92911924A EP92911924A EP0589958A4 EP 0589958 A4 EP0589958 A4 EP 0589958A4 EP 92911924 A EP92911924 A EP 92911924A EP 92911924 A EP92911924 A EP 92911924A EP 0589958 A4 EP0589958 A4 EP 0589958A4
Authority
EP
European Patent Office
Prior art keywords
specific nucleases
universal site
universal
site
nucleases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92911924A
Other languages
German (de)
French (fr)
Other versions
EP0589958A1 (en
Inventor
Yie-Hwa Chang
John A Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of EP0589958A1 publication Critical patent/EP0589958A1/en
Publication of EP0589958A4 publication Critical patent/EP0589958A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/22—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a Strep-tag
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3513—Protein; Peptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP92911924A 1991-06-11 1992-05-06 Universal site-specific nucleases. Withdrawn EP0589958A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71290591A 1991-06-11 1991-06-11
US712905 1991-06-11
PCT/US1992/003793 WO1992022642A1 (en) 1991-06-11 1992-05-06 Universal site-specific nucleases

Publications (2)

Publication Number Publication Date
EP0589958A1 EP0589958A1 (en) 1994-04-06
EP0589958A4 true EP0589958A4 (en) 1995-04-26

Family

ID=24864017

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92911924A Withdrawn EP0589958A4 (en) 1991-06-11 1992-05-06 Universal site-specific nucleases.

Country Status (7)

Country Link
EP (1) EP0589958A4 (en)
JP (1) JPH06510901A (en)
AU (1) AU1972392A (en)
CA (1) CA2108134A1 (en)
IL (1) IL101837A0 (en)
NZ (1) NZ242694A (en)
WO (1) WO1992022642A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436150A (en) * 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
ATE239785T1 (en) * 1993-02-12 2003-05-15 Univ Johns Hopkins FUNCTIONAL DOMAIN OF THE RESTRICTION ENDONUCLEASES FROM -I(FLAVOBACTERIUM OKEANOKOITES)(FOKI)
CN111751540B (en) * 2020-07-20 2023-03-03 烟台大学 SERS lateral flow test strip for nuclease detection and detection method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
C. HÉLÈNE ET AL: "Sequence-specific artificial endonucleases", TRENDS IN BIOTECHNOLOGY., vol. 7, November 1989 (1989-11-01), CAMBRIDGE GB, pages 310 - 315 *

Also Published As

Publication number Publication date
IL101837A0 (en) 1992-12-30
NZ242694A (en) 1993-07-27
JPH06510901A (en) 1994-12-08
CA2108134A1 (en) 1992-12-12
EP0589958A1 (en) 1994-04-06
AU1972392A (en) 1993-01-12
WO1992022642A1 (en) 1992-12-23

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19931027

AK Designated contracting states

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Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

RHK1 Main classification (correction)

Ipc: C12N 15/62

A4 Supplementary search report drawn up and despatched

Effective date: 19950308

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18W Application withdrawn

Withdrawal date: 19950517