EP0587777A4 - Cea-binding proteins and methods for their isolation and use. - Google Patents

Cea-binding proteins and methods for their isolation and use.

Info

Publication number
EP0587777A4
EP0587777A4 EP92913689A EP92913689A EP0587777A4 EP 0587777 A4 EP0587777 A4 EP 0587777A4 EP 92913689 A EP92913689 A EP 92913689A EP 92913689 A EP92913689 A EP 92913689A EP 0587777 A4 EP0587777 A4 EP 0587777A4
Authority
EP
European Patent Office
Prior art keywords
cea
isolation
methods
binding proteins
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92913689A
Other languages
German (de)
French (fr)
Other versions
EP0587777A1 (en
Inventor
Peter Thomas
Carol A Toth
Sibusisiwe M Maswoswe
Joseph V Briggman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
New England Deaconess Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/708,888 external-priority patent/US5281697A/en
Priority claimed from US07/708,885 external-priority patent/US5245017A/en
Priority claimed from US07/714,386 external-priority patent/US5278290A/en
Application filed by New England Deaconess Hospital filed Critical New England Deaconess Hospital
Publication of EP0587777A1 publication Critical patent/EP0587777A1/en
Publication of EP0587777A4 publication Critical patent/EP0587777A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP92913689A 1991-05-31 1992-05-22 Cea-binding proteins and methods for their isolation and use. Withdrawn EP0587777A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US07/708,888 US5281697A (en) 1991-05-31 1991-05-31 CEA-binding protein and uses thereof
US708888 1991-05-31
US714386 1991-05-31
US07/708,885 US5245017A (en) 1991-05-31 1991-05-31 Method for isolating CEA-binding protein
US708885 1991-05-31
US07/714,386 US5278290A (en) 1991-05-31 1991-05-31 Binding protein for CEA and uses thereof

Publications (2)

Publication Number Publication Date
EP0587777A1 EP0587777A1 (en) 1994-03-23
EP0587777A4 true EP0587777A4 (en) 1995-05-10

Family

ID=27418849

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92913689A Withdrawn EP0587777A4 (en) 1991-05-31 1992-05-22 Cea-binding proteins and methods for their isolation and use.

Country Status (3)

Country Link
EP (1) EP0587777A4 (en)
AU (1) AU2158292A (en)
WO (1) WO1992021364A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774209B1 (en) 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
AU2003291483A1 (en) 2002-11-12 2004-06-03 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
KR20080006617A (en) 2005-04-15 2008-01-16 백톤 디킨슨 앤드 컴퍼니 Diagnosis of sepsis
CA2708004C (en) 2006-12-04 2015-12-01 Promedior, Inc. Conjoint therapy for treating fibrotic diseases
HUE026850T2 (en) * 2007-07-06 2016-08-29 Promedior Inc Methods and compositions useful in the treatment of mucositis
US9884899B2 (en) 2007-07-06 2018-02-06 Promedior, Inc. Methods for treating fibrosis using CRP antagonists
US8497243B2 (en) 2007-07-06 2013-07-30 Promedior, Inc. Methods and compositions useful in the treatment of mucositis
WO2009123737A2 (en) 2008-04-03 2009-10-08 Becton, Dickinson And Company Advanced detection of sepsis
CA2754961C (en) 2009-03-11 2018-04-10 Promedior, Inc. Treatment and diagnostic methods for hypersensitive disorders
AU2010224172B2 (en) 2009-03-11 2016-01-21 Promedior, Inc. Treatment methods for autoimmune disorders
UA110323C2 (en) 2009-06-04 2015-12-25 Promedior Inc Derivative of serum amyloid p and their receipt and application
HUE041034T2 (en) 2009-06-17 2019-05-28 Promedior Inc Sap variants and their use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732862A (en) * 1983-11-21 1988-03-22 Alberto Bartorelli Determination of CEA binding substance using anti-goat immunoglobulins
WO1989008255A1 (en) * 1988-03-04 1989-09-08 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8516081D0 (en) * 1985-06-25 1985-07-31 Ciba Geigy Ag Assay & purification of amyloid components
US4892933A (en) * 1988-04-20 1990-01-09 New England Deaconess Hospital Corporation Monoclonal antibody for colorectal carcinoma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732862A (en) * 1983-11-21 1988-03-22 Alberto Bartorelli Determination of CEA binding substance using anti-goat immunoglobulins
WO1989008255A1 (en) * 1988-03-04 1989-09-08 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BARTORELLI A., BIOMEDICINE AND PHARMACOTHERAPY, vol. 41, no. 1, 1987, pages 2 - 5 *
See also references of WO9221364A1 *
THOMAS P., ET AL., FASEB JOURNAL, vol. 2, no. 4, 1988, BETHESDA, MD US, pages A623 *
TOTH C.A., ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 171, no. 2, 1990, DULUTH, MINNESOTA US, pages 633 - 640 *

Also Published As

Publication number Publication date
EP0587777A1 (en) 1994-03-23
AU2158292A (en) 1993-01-08
WO1992021364A1 (en) 1992-12-10

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