EP0581906A4 - Abrogation of viral resistance to nucleoside analogues by double-stranded rnas - Google Patents

Abrogation of viral resistance to nucleoside analogues by double-stranded rnas

Info

Publication number
EP0581906A4
EP0581906A4 EP92917298A EP92917298A EP0581906A4 EP 0581906 A4 EP0581906 A4 EP 0581906A4 EP 92917298 A EP92917298 A EP 92917298A EP 92917298 A EP92917298 A EP 92917298A EP 0581906 A4 EP0581906 A4 EP 0581906A4
Authority
EP
European Patent Office
Prior art keywords
abrogation
double
nucleoside analogues
stranded rnas
viral resistance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92917298A
Other versions
EP0581906A1 (en
Inventor
William Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEM Pharmaceuticals Corp
Original Assignee
HEM Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEM Pharmaceuticals Corp filed Critical HEM Pharmaceuticals Corp
Publication of EP0581906A1 publication Critical patent/EP0581906A1/en
Publication of EP0581906A4 publication Critical patent/EP0581906A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EP92917298A 1991-04-16 1992-03-12 Abrogation of viral resistance to nucleoside analogues by double-stranded rnas Withdrawn EP0581906A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68620091A 1991-04-16 1991-04-16
US686200 1991-04-16

Publications (2)

Publication Number Publication Date
EP0581906A1 EP0581906A1 (en) 1994-02-09
EP0581906A4 true EP0581906A4 (en) 1997-07-23

Family

ID=24755338

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92917298A Withdrawn EP0581906A4 (en) 1991-04-16 1992-03-12 Abrogation of viral resistance to nucleoside analogues by double-stranded rnas

Country Status (10)

Country Link
EP (1) EP0581906A4 (en)
JP (1) JPH06507624A (en)
CN (1) CN1082819C (en)
AU (1) AU671800B2 (en)
CA (1) CA2102221A1 (en)
IE (1) IE920873A1 (en)
MX (1) MX9201711A (en)
PT (1) PT100340A (en)
WO (1) WO1992018004A1 (en)
ZA (1) ZA922755B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286224A2 (en) * 1987-03-23 1988-10-12 Hem Pharmaceuticals Corp. Treatment of human viral infection by dsRNA combined with viral inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820696A (en) * 1985-08-26 1989-04-11 Hem Research, Inc. Modulation of aids virus-related events by double-stranded RNAS
US4795744A (en) * 1986-07-17 1989-01-03 Hem Research, Inc. Modulation of AIDS virus-related events by double-stranded RNAS
US4945082A (en) * 1985-08-26 1990-07-31 Hem Research, Inc. Controlled dsRNA therapy for human viral infections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286224A2 (en) * 1987-03-23 1988-10-12 Hem Pharmaceuticals Corp. Treatment of human viral infection by dsRNA combined with viral inhibitors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CARTER W.A. ET AL: "Mismatched double-stranded RNA, Ampligen (poly(I):poly(C12U)), demonstrates antiviral and immunostimulatory activities in HIV disease", INT. J. IMMUNOPHARM., 1991, 13/SUPPL. I (69-76), UNITED KINGDOM, XP000670844 *
MONTEFIORI D C ET AL: "IN-VITRO EVALUATION OF MISMATCHED DOUBLE-STRANDED RNA AMPLIGEN FOR COMBINATION THERAPY IN THE TREATMENT OF ACQUIRED IMMUNODEFICIENCY SYNDROME", AIDS RES HUM RETROVIRUSES, 5 (2). 1989. 193-204., XP000647024 *
See also references of WO9218004A1 *

Also Published As

Publication number Publication date
CN1082819C (en) 2002-04-17
CA2102221A1 (en) 1992-10-17
AU671800B2 (en) 1996-09-12
EP0581906A1 (en) 1994-02-09
WO1992018004A1 (en) 1992-10-29
AU1871892A (en) 1992-11-17
IE920873A1 (en) 1992-10-21
ZA922755B (en) 1993-04-28
MX9201711A (en) 1992-10-01
JPH06507624A (en) 1994-09-01
PT100340A (en) 1993-07-30
CN1068035A (en) 1993-01-20

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19931019

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Effective date: 19990202