EP0576596A4 - - Google Patents

Info

Publication number
EP0576596A4
EP0576596A4 EP19920909864 EP92909864A EP0576596A4 EP 0576596 A4 EP0576596 A4 EP 0576596A4 EP 19920909864 EP19920909864 EP 19920909864 EP 92909864 A EP92909864 A EP 92909864A EP 0576596 A4 EP0576596 A4 EP 0576596A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19920909864
Other versions
EP0576596A1 (en
Inventor
Stephen A. Blum
Robert D. Goodband
Jim L. Nelssen
Larry G. Newton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza LLC
University of Georgia Research Foundation Inc
Kansas State University
Original Assignee
Lonza LLC
University of Georgia Research Foundation Inc
Kansas State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza LLC, University of Georgia Research Foundation Inc, Kansas State University filed Critical Lonza LLC
Publication of EP0576596A1 publication Critical patent/EP0576596A1/en
Publication of EP0576596A4 publication Critical patent/EP0576596A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds

Definitions

  • starter pigs earl weaned pigs
  • HNDD high nutrient-densit diet
  • the L-carnitine actually partitions the nutrients so as to favor lean accretion, despite the already lean state of the animal, while at the same time allowing sufficient fat to form as is necessary for normal growth.
  • the feed regimen be commenced at a time when the endogenous carnitine synthesis is very low, i.e., preferably in the period when the pig is less than about 24 days of age and when the pig is growing at or near its true genetic potential.
  • the response to the carnitine-supplemented HNDD will, of course, be more pronounced for genotypes having high lean growth capacities.
  • starter pigs from birth up to 24 days of age having an initial weight of from 3 to 16 pounds are fed the diet of the invention in at least two, preferably in three, phases.
  • the Phase 1 diet is for a period of from one to three weeks, preferably two weeks or until the body weight is about 15 pounds, and contains from about 5 to 5000 ppm of L-carnitine, preferably about 500 to 2000 ppm, optimally about 1000 ppm.
  • Phase 2 commenced when the pig is about 35 days old, the diet is administered from two to four weeks after Phase 1, preferably for three additional weeks.
  • the L-car- nitine is optimally reduced to 500 ppm, but amounts between 25 and 1000 ppm are also effective.
  • L-carnitine as feed supplement may be advantageous in both the grower stag (i.e., up to a weight of 160 pounds; approximately 130 days o age) and the finishing stage.
  • the amount of carnitine would be gradually reduce from 500 to 5 ppm.
  • the maximum during finishing is 50 ppm desirably from 5 to 50 ppm.
  • the optimum amount of carnitine decreases.
  • Phase 2 1.25% lysine, whey. Fed to pigs from 15 to corn-soybean diet 25 lb.
  • Phase 3 1.10% lysine, grain- Fed to pigs until body soybean diet weight is approx. 50 lb.
  • HNDD high nutrient-density diet
  • HNDD HNDD
  • Table Char cte istics of a ree-Phase a t r Pro ram
  • the Phase 1 diets (which ar supplemented with carnitine in accordance with the practice o the instant invention) contain at least 15%, preferably from 1 to 30%, protein; from 30 to 45% dried milk products such a light edible whey, dried skim milk, and casein; and from 5 t 15% added fat.
  • the protein is decreased to less than 25%, preferably from 15 to 25%; the dried milk products to less than 25%, preferably from 10 to 25%; and the added fat to from about 1 to 5%.
  • Phase 3 the diet maintains about the same per ⁇ centage of protein as in Phase 2, the dried milk products are reduced to less than 10%, and the added fat substantially eliminated.
  • milk products is used in the above description, it should be understood that this term is intended to include nutritional products which are derived from other sources and have compositions substantially similar to those derived from milk.
  • soy protein concentrates made by extracting soy flour with ethanol to reduce the carbohydrate content
  • soy isolates which further concentrate the protein by acid extracting soy flour with acid
  • plasma protein which is obtained by the spray drying of porcine or bovine plasma.
  • the essential factor is to obtain a protein source that has a solids content similar to that in the mother's milk, i.e., that is highly digestible protein, very low in carbohydrates with little antigenicity.
  • the diet is fed on an ad libitum basis in the form of pellets or ground to form a meal, depending on the age of the pig.
  • the appropriate form of the feed is well known to those skilled in the art, as are the feeding regimens, that is, the frequency and amount of diet fed to the animals. Those skilled in the art may readily determine the amount o total feed at the various stages of pig development.
  • the intake of the diet of the invention should average greater than 345 grams per day for the first two weeks, and average greater than 725 grams per day for the following three weeks. An average over 600 grams per day over the five weeks is also effective.
  • Example One hundred eighty weanling pigs (22 ⁇ 2 days of age, initial weight 6 kg) were used to show the effect of feeding nursery pigs L-carnitine on pig performance and carcass composition.
  • the experimental design consisted of a 2 x 3 factorial arrangement with 0 or 1000 ppm L-carnitine fed in Phase 1 (0 to 2 weeks) combined with 0, 250 or 500 ppm L- carnitine in Phase 2 (3 to 5 weeks).
  • Phase 1 diets contained 20% dried skim milk, 20% dried whey, 5% soybean oil and were formulated to contain 1.45% lysine.
  • Phase 2 diets contained 10% dried whey, 5% soybean oil and were formulated to contain 1.25% lysine.
  • Carcass dry matter (DM) and crude protein (CP) were not influenced (P>.15) by dietary L- carnitine on day 14 or 25. Percent carcass lipid was not affected by dietary treatment on day 14; however, pigs fed 1000 ppm L-carnitine in Phase 1 had less (P ⁇ .05) daily fat accretion (DFA) on day 35 regardless of whether they were fed carnitine in Phase 2 or not. Based on the results of this experiment, L- carnitine addition reduces carcass fat when fed in Phase 1 and improves F/G when fed in Phase 2.
  • DFA daily fat accretion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
EP92909864A 1991-03-22 1992-01-29 Carnitine-supplemented diet for starter pigs Withdrawn EP0576596A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67398691A 1991-03-22 1991-03-22
US673986 1991-03-22

Publications (2)

Publication Number Publication Date
EP0576596A1 EP0576596A1 (en) 1994-01-05
EP0576596A4 true EP0576596A4 (Direct) 1994-02-23

Family

ID=24704883

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92909864A Withdrawn EP0576596A1 (en) 1991-03-22 1992-01-29 Carnitine-supplemented diet for starter pigs

Country Status (5)

Country Link
EP (1) EP0576596A1 (Direct)
JP (1) JP2667055B2 (Direct)
AU (1) AU1888292A (Direct)
CA (1) CA2106274C (Direct)
WO (1) WO1992016218A1 (Direct)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ508798A (en) * 1998-06-26 2003-03-28 Iams Company Pet food composition comprising L-carnitine, and its use in the manufacture of pet food products for promoting weight loss and/or increasing lean body mass and/or enhancing the satiety and decreasing voluntary food intake in overweight dogs
US6630159B2 (en) 1999-02-23 2003-10-07 The Procter & Gamble Company Limiting weight gain of cats by feeding carbohydrate source that excludes rice
US7001618B1 (en) 1999-07-09 2006-02-21 The Iams Company Nutritional composition for weight management
CN107494969A (zh) * 2017-08-29 2017-12-22 贵州省原态上品农业科技有限责任公司 一种断奶仔猪专用饲料及其制备方法
JP7337499B2 (ja) * 2017-12-19 2023-09-04 日本ニュートリション株式会社 豚用飼料添加物および哺乳子豚の発育改善方法
CN111601512B (zh) * 2019-03-06 2023-11-17 彭险峰 γ-季铵基丁酸酯类化合物在制备动物饲料添加剂中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125674A (en) 1960-10-10 1964-03-17 Full binary adder including negative resistance diode
US3810994A (en) * 1972-06-01 1974-05-14 Ethyl Corp Method and composition for treating obesity

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9216218A1 *

Also Published As

Publication number Publication date
WO1992016218A1 (en) 1992-10-01
AU1888292A (en) 1992-10-21
CA2106274C (en) 1998-08-04
JP2667055B2 (ja) 1997-10-22
CA2106274A1 (en) 1992-09-23
EP0576596A1 (en) 1994-01-05
JPH06507784A (ja) 1994-09-08

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Withdrawal date: 19980716