EP0563100A1 - Instructions or analogous element for medicaments. - Google Patents
Instructions or analogous element for medicaments.Info
- Publication number
- EP0563100A1 EP0563100A1 EP92900725A EP92900725A EP0563100A1 EP 0563100 A1 EP0563100 A1 EP 0563100A1 EP 92900725 A EP92900725 A EP 92900725A EP 92900725 A EP92900725 A EP 92900725A EP 0563100 A1 EP0563100 A1 EP 0563100A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- time
- instructions
- signal
- analogous element
- intervals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G04—HOROLOGY
- G04F—TIME-INTERVAL MEASURING
- G04F3/00—Apparatus which can be set and started to measure-off predetermined or adjustably-fixed time intervals with driving mechanisms, e.g. dosimeters with clockwork
- G04F3/02—Apparatus which can be set and started to measure-off predetermined or adjustably-fixed time intervals with driving mechanisms, e.g. dosimeters with clockwork with mechanical driving mechanisms
- G04F3/027—Apparatus which can be set and started to measure-off predetermined or adjustably-fixed time intervals with driving mechanisms, e.g. dosimeters with clockwork with mechanical driving mechanisms using electrical contacts, e.g. for actuating electro-acoustic device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2205/00—General identification or selection means
- A61J2205/70—Audible labels, e.g. for pre-recorded info or messages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
Definitions
- the invention relates to a new type of instructions or analogous element for medicaments which preferably give a.o. indications for the use of the concerned medicaments, and which comprise means for producing a signal, such as a sound and/or light signal, on predetermined points of time which correspond to those on which the medicaments should be used.
- medecine With the use of medecines, it is of the utmost importance that the medecine is taken at the right point of time. Take for instance an antibiotic cure, for which the antibiotic should be taken every six hours to keep the concentration of the antibiotic in the blood at such an effective level that the pathogenic micro-organisms will not survive. If the - 2
- antibiotic is not taken in time or if a dose is skipped, one runs the risk of a revival of the micro ⁇ organism, after which the chance of success of the therapy can strongly decrease.
- the number of administrations a day can be different, while the intervals of time between two successive administrations can also vary during the day. Moreover, for certain medicaments, the number of administrations and/or the intervals of time between two successive administrations can also vary from day to day. It is for instance possible that the number of administrations decreases day after day and inversely the intervals of time between two successive administrations increase day after day. It has further to be emphasized that the cycles of administration of a specific medicament can also depend from the patient himself.
- the dispenser who gives the medecine, files the medication data per patient in the memory of a computer, which calculates the consumption period and gives a signal if the patient comes too early for a new amount of the concerned medecine.
- the invention mainly has as purpose to give a solution to all the above cited situations and to remedy the shortcomings of the different above described methods not only on an economically sound manner but also on a very simple way so that all possible mistakes in the administration times will be excluded.
- the means for emitting or producing a signal on predetermined periods or points of time corresponding to those on which the medicament should be used comprise an electronic timer connected to a signal producing device for activating said signal, which timer being preprogrammed in such a way as to be able to activate said signal after successive intervals of time of one or more cycles of such intervals, said intervals being identical or different, the latter being further defined with respect to a starting reference point of time for said cycles, an operating organ being provided for setting up, by means of said timer, a specific cycle at a starting reference point of time which preferably corresponds to the point of time that the medicament has to be used for the first time, the end of each interval corresponding to the point of time a next dose of the medicament should be used when starting the cycle at the reference point of time.
- these means include also a "reset" switch which permits to erase the possibly already regulated points of time and to define a new first point of time on which all the subsequent points depend automatically.
- the instructions or the analogous element is made out of a relatively stiff little plate, for example of plastificized or not plastificized cardboard, onto which possibly certain inscriptions are made and which e.g. can be ranged in detachable fashion in a packing of the medicaments.
- Figure 1 is a frontal view of instructions made of a stiff rectangular card according to the invention.
- Figure 2 is a rear view of the same instructions.
- Figure 3 represents a block diagram of the in this instruction built in electronic circuit according to the invention.
- Figure 4a represents a portion of more detailed- block diagram of an electronic part of a specific embodiment of the instructions according to the invention.
- Figure 4b represents the other portion z f the same block diagram, as referred to in figure 4a.
- the general idea on which the present invention is based is to draw the attention of the patient, each time he has to use a medecine, to this fact in an active manner, such that the factor forgetfullness is entirely eliminated.
- instructions or instruction enclosure
- analogous element which includes means for generating a sound signal on points of time which in a simple manner can be regulated beforehand and correspond to those on which the concerned medicament should be used.
- This instruction enclosure is made out of a cardboard card of very limited dimension such that it can be enclosed into the packing of the medecines. It is, for example, a rectangular card which has the standardized dimensions of a bank card or a credit card and, therefore, can be taken along in the same manner as such a bank card or credit card in a 'wallet or diary, such that one always carries the instructions about.
- a sound signal is generated by means of a piezo-elect ⁇ c buzzer provided with a so-called “Helmholz resonator ("piezo- buzzer”) 10 as represented schematically in figure 3.
- the instructions include further a so-called "reset" switch 4, which in practice is made up by a small push button sunk in the left top corner of the front side 1a of this card 1 and which can be operated via a small circular hole in the upper carboard layer by means of a pointed object. In this manner, it is avoided that by an accidental touch this switch 4 would be operated.
- This switch 4 enables to stop the possible cycle of successive points of time and if necessary to start again on another moment a new cycle.
- the sound signal can be combined or replaced by a spoken short text in connection with the use of the medecine.
- This specific embodiment was not represented in the figures but the technique for this is known in itself e.g. in certain postcards.
- means are provided to give together with this sound signal a light signal.
- a light-emitting diode known by the name "LED” 3 (see figure 3).
- This electronic circuit 9 includes a programmed time regulator or timer 11, which is made up of a so-called “customised CMOS timer". On this time regulator 11 the different functions to be operated, such as the sound signal, the light signal and the
- 1 4 11 is further connected to a battery 12 which provides the necessary energy supply, the battery in turn being in a series with the "reset" switch 4.
- the embodiment of the instructions represented in the figures according to the invention shows four different push buttons 2 which each permits to operate one of the switches S , S , S or S .
- buttons are numbered from 1 to 4. The key with number
- the key number 2 relates to a medicament which has to be used twice a day.
- the key with number 3 it is three times a day and for the key with number 4 it is four times a day. If, for example for a diuretic, a dose of one table once a day at 8 o'clock in the morning is prescribed, it suffices at the first use at 8 o'clock in the morning to press first the reset switch 4 and next the push button with number 1. In this manner, after an interval of time of 24 hours, so each time at 8 o'clock in the morning, a sound signal will be made by buzzer 10 and at the same time the "LED" diode 3 will flash.
- the time regulator 11 can be regulated so that the sound signal and the light signal remain working for a specific number of seconds after which they are automatically switched off. Possibly an extra button could be provided to switch off these signals within this period of time. If for example it is provided that these signals can be sustained for ten seconds, this extra button could thus take care that these signals are switched off sooner, the aim being not to disturb possible persons in the neighbourhood.
- the signals will be emitted for one medicament f.i. at 9 o'clock (9 a.m.) and at 21 o'clock (9 p.m.) and for another medicament f.i. at 9 o'clock (9 a.m.) and at 18 o'clock (6 p.m.).
- the sleeping period With the use of three times a day one must take into account the sleeping period. If it is accepted that the period of sleeping amounts on average to ten hours, including making one's toilet before and after sleeping, then it is for example possible to give a signal every seven hours. If one sets the first signal at 8 o'clcock then a signal will be given also at 15 o'clock and 23 o'clock. With the use of four times a day the interval of time will preferably amount to five hours, which implies that the signals are given at the following points of time : 8 o'clock, 13 o'clock, 18 o'clock and 23 o'clock. The benefit of the "reset" switch is that it allows to change the time for the first use.
- time regulator or timer 11 has two different states : a state of rest and an active state.
- the manufacturer of the medicament and. or the pharmacist add to the medicament a programmed instruction enclosure in state of rest.
- the patient brings the timer 11 in active state at the moment the first dose of the medicament has to be taken bv acting on the corresponding operating organ 2 comprising switches S , S , S and S , depending from the
- the switches S , S , S , S which are f.i. diaphragm switches, can be replaced by detectors from a quite different type, as long as they have the same function as these switches.
- the circuit can be energized by a switch 21.
- This switch connects a small battery to the integrated oscillator and frequency divider 22.
- This frequency divider 22 is connected to the quartz cristal 23. The result will be an oscillation at the frequency determined by the quartz cristal 23.
- This method of providing a stable and reliable time base is also used in so-called "quartz clocks".
- a second frequency divider 24 divides the output frequency of frequency divider 22 to the time base required for a certain medicine.
- the flip-flop circuits 25 and 26 will be set.
- the output of flip-flop 25 will enable the AND gate 27 which AND's the enable signal from flip-flop 25 with a short repeated pulse generated by the first divider 22 and a differentiating network 28.
- the output of gate 27 drives an emitter-follower which switches the energy stored in capacitor 30 to the LED 29.
- flip-flop 26 and gate 31.
- the output from flip-flop 26 is AND gated with a 4 kHz tone generated by the frequency divider 22, inverted and again AND gated by gates 32 and 33 with a pulse to make the 4 kHz tone intermittent.
- the signal is inverted by two parallel inverters 33 and 34 in order to generate sufficient drive for a oiezo-electric audible transducer 10.
- the flip-flop 26 is reset after approximately 10 seconds, so that audible signal will only be heard during that time.
- the circuits are build using C-MDS logic circuits. This ensures an extremly low power consumption.
- the circuit will operate at a set of batteries as used in electronic watches from one month to more than a year, depending from the frequency and the circuit used.
- the invention is of course in no way limited to the specific embodiments of the instructions described above, but within the framework of the invention and the protection claimed, several changes can be considered, a.o. concerning the relative arrangement of the component parts of the card, such as in relation to the push buttons 2, the light-emitting diode 3, the reset switch 4, the composition and the units of the electronic circuit 9, etc. Also the shape of the instructions can be very different.
- the instructions or analogous element according to the invention should comprise an electronic timer or time regulator 11 connected to a sound signal producing device, such as a piezo-buzzer 10, and possibly to a light signal producing device, such as a LED 3 for activating said signal.
- a sound signal producing device such as a piezo-buzzer 10
- a light signal producing device such as a LED 3 for activating said signal.
- This timer should further be programmed on beforehand in such a - M -
- an operating organ 2 should be provided for starting this cycle of intervals of time at such moment of the day so that the end of each of these intervals will automatically correspond to a point of time of the day on which the medicament should be taken.
- the intervals of time of a cycle are thus defined with respect to a starting reference point of time.
- This starting reference point of time corresponds preferably to the moment of the day the medicament has to be administered for the first time.
- the length of a specific interval of time should correspond to a corresponding space of time between two successive points of time so that when the timer is activated on the right moment, the end of each interval of time will automatically correspond to a point of time of the day on which the medicament should be taken.
- analogous element is meant every bearer, suitable for housing means which allows for the emission of a sound signal and possibly a light signal and which is such that it can play a role substantially similar to the above described and in the figures represented card. Hence this means that the patient must be able to carry along this bearer in a simple and discrete manner such that when a sound signal is generated this is easily audible to him. Hence it follows that for example could be thought of a bracelet, a necklace, etc.
- a card When use is made of a card, the latter could for example be provided with a sticker or stick-on surface, thanks to which the card can be fixed in a detachable way e.g. inside a garment, such as a shirt or blouse.
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Electric Clocks (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Abstract
Dispositif donnant des indications ou analogue concernant l'administration d'un médicament. Il comporte un émetteur (9) destiné à émettre un signal sonore à des momemts prédéterminés qui correspondent aux moments auxquels l'on doit utiliser le médicament.Device giving indications or the like concerning the administration of a medicament. It comprises a transmitter (9) intended to emit an audible signal at predetermined times which correspond to the moments at which the drug must be used.
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP90203519 | 1990-12-21 | ||
EP90203519 | 1990-12-21 | ||
PCT/EP1991/002421 WO1992011587A1 (en) | 1990-12-21 | 1991-12-14 | Instructions or analogous element for medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0563100A1 true EP0563100A1 (en) | 1993-10-06 |
EP0563100B1 EP0563100B1 (en) | 1995-02-22 |
Family
ID=8205217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP92900725A Expired - Lifetime EP0563100B1 (en) | 1990-12-21 | 1991-12-14 | Instructions or analogous element for medicaments |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0563100B1 (en) |
JP (1) | JP2964426B2 (en) |
DE (1) | DE69107628T2 (en) |
ES (1) | ES2070624T3 (en) |
WO (1) | WO1992011587A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1014438C2 (en) * | 2000-02-21 | 2001-08-22 | Organon Nv | Electronic timer with alarm for use during a medical treatment. |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554967A (en) * | 1994-07-08 | 1996-09-10 | Smithkline Beecham Corp. | Reminder device |
US6018289A (en) * | 1995-06-15 | 2000-01-25 | Sekura; Ronald D. | Prescription compliance device and method of using device |
ES1032714Y (en) * | 1995-12-13 | 1996-11-01 | Galvez Jose Rubio | AUTOMATIC OPERATING NOTICE AT FIXED INTERVALS. |
FR2775087B1 (en) * | 1998-02-13 | 2000-08-25 | Philippe Gaillet | ELECTRONIC TIMER IN THE FORM OF A CREDIT CARD |
NL2001365C2 (en) | 2008-03-12 | 2009-09-15 | Bart Theodoor Hogebrink | Programmable device for signaling a time-bound activity. |
JP2013244373A (en) * | 2012-05-29 | 2013-12-09 | Seki Nobuko | Medicine storage box with function for preventing failure to take medicine |
KR101428530B1 (en) | 2014-01-21 | 2014-08-11 | 주식회사 예진 | natural dyed portable medication storage device for tell you the time to take medications |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5682483A (en) * | 1979-12-11 | 1981-07-06 | Casio Comput Co Ltd | Electronic timepiece with sound recording function |
US4490711A (en) * | 1981-12-21 | 1984-12-25 | Johnston Robert W | Electronic programmable multiple alarm timing device and record |
US4504153A (en) * | 1983-08-08 | 1985-03-12 | R. Dean Seeman | Pharmacist-programmable medication prompting system and method |
EP0159306A1 (en) | 1984-03-02 | 1985-10-23 | de Prelle de la Nieppe, Cedric L. | Apparatus for supervising the taking of pills |
US4725997A (en) | 1986-08-22 | 1988-02-16 | Aprex Corporation | Contingent dosing device |
JPS63160898A (en) * | 1986-12-25 | 1988-07-04 | 株式会社東芝 | Ic card for prescribing medicine |
US4730849A (en) * | 1987-02-05 | 1988-03-15 | Seigel Family Revocable Trust | Medication dispensing identifier method |
DE3705965A1 (en) * | 1987-02-25 | 1988-09-08 | Hensch Friedrich | Programmed timer |
US4849948A (en) * | 1987-05-06 | 1989-07-18 | Medalarm Corporation | Self-contained disposable timer for use with medication |
GB2205306A (en) * | 1987-06-04 | 1988-12-07 | Susan Ellen Barham | Automatic medication dispenser |
JPH02257960A (en) * | 1989-03-31 | 1990-10-18 | Nisshin Flour Milling Co Ltd | Medicine taking time alarming device |
-
1991
- 1991-12-14 WO PCT/EP1991/002421 patent/WO1992011587A1/en active IP Right Grant
- 1991-12-14 JP JP4501656A patent/JP2964426B2/en not_active Expired - Lifetime
- 1991-12-14 EP EP92900725A patent/EP0563100B1/en not_active Expired - Lifetime
- 1991-12-14 ES ES92900725T patent/ES2070624T3/en not_active Expired - Lifetime
- 1991-12-14 DE DE69107628T patent/DE69107628T2/en not_active Expired - Fee Related
Non-Patent Citations (1)
Title |
---|
See references of WO9211587A1 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1014438C2 (en) * | 2000-02-21 | 2001-08-22 | Organon Nv | Electronic timer with alarm for use during a medical treatment. |
WO2001064161A1 (en) * | 2000-02-21 | 2001-09-07 | Akzo Nobel N.V. | Electronic alarm timer for use with a medical regimen |
Also Published As
Publication number | Publication date |
---|---|
WO1992011587A1 (en) | 1992-07-09 |
EP0563100B1 (en) | 1995-02-22 |
JPH06504122A (en) | 1994-05-12 |
JP2964426B2 (en) | 1999-10-18 |
ES2070624T3 (en) | 1995-06-01 |
DE69107628D1 (en) | 1995-03-30 |
DE69107628T2 (en) | 1995-10-05 |
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