EP0511300A4 - Monoclonal antibody specific for non-immunodominant epitope of hiv proteins - Google Patents
Monoclonal antibody specific for non-immunodominant epitope of hiv proteinsInfo
- Publication number
- EP0511300A4 EP0511300A4 EP19910903736 EP91903736A EP0511300A4 EP 0511300 A4 EP0511300 A4 EP 0511300A4 EP 19910903736 EP19910903736 EP 19910903736 EP 91903736 A EP91903736 A EP 91903736A EP 0511300 A4 EP0511300 A4 EP 0511300A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- monoclonal antibody
- antibody specific
- immunodominant epitope
- hiv proteins
- hiv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6839—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting material from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46503590A | 1990-01-16 | 1990-01-16 | |
US465035 | 1990-01-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0511300A1 EP0511300A1 (en) | 1992-11-04 |
EP0511300A4 true EP0511300A4 (en) | 1993-05-26 |
Family
ID=23846250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19910903736 Withdrawn EP0511300A4 (en) | 1990-01-16 | 1991-01-16 | Monoclonal antibody specific for non-immunodominant epitope of hiv proteins |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0511300A4 (en) |
JP (1) | JPH05506142A (en) |
CA (1) | CA2073060A1 (en) |
WO (1) | WO1991010742A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0554401A4 (en) * | 1990-10-26 | 1996-10-30 | New York Health Res Inst | Neutralizing human monoclonal antibodies specific for the v3 loop and cd-4 binding site of hiv-1 gp120 |
US6797492B2 (en) | 1991-05-17 | 2004-09-28 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
DE19809785C2 (en) * | 1998-03-08 | 2000-02-10 | Wolfgang Bergter | Radioimmune drug for the treatment of HIV-1 infection |
US8481041B2 (en) | 2005-04-06 | 2013-07-09 | Ibc Pharmaceuticals, Inc. | Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy |
US20100266620A1 (en) * | 2006-01-20 | 2010-10-21 | Le Sun | Immunoconjugates for treatment of infectious diseases |
EP2016173A4 (en) * | 2006-05-15 | 2010-06-09 | Immunomedics Inc | Methods and compositions for treatment of human immunodeficiency virus infection with conjugated antibodies or antibody fragments |
WO2016191481A1 (en) | 2015-05-28 | 2016-12-01 | Immunomedics, Inc. | T20 constructs for anti-hiv (human immunodeficiency virus) therapy and/or vaccines |
CN108779168A (en) | 2015-12-05 | 2018-11-09 | 沃迪奥斯大学医院中心 | HIV bonding agents |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988005824A1 (en) * | 1987-02-02 | 1988-08-11 | E.I. Du Pont De Nemours And Company | Selection of monoclonal antibodies to viral glycoproteins |
US4861707A (en) * | 1987-02-02 | 1989-08-29 | E. I. Du Pont De Nemours And Company | Human immunodeficiency virus antigen |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2437213A1 (en) * | 1978-09-28 | 1980-04-25 | Cm Ind | CYTOTOXIC PRODUCTS FORMED BY COVALENT BINDING OF THE CHAIN TO RICIN WITH AN ANTIBODY AND THEIR PREPARATION METHOD |
-
1991
- 1991-01-16 JP JP91503590A patent/JPH05506142A/en active Pending
- 1991-01-16 WO PCT/US1991/000319 patent/WO1991010742A1/en not_active Application Discontinuation
- 1991-01-16 CA CA002073060A patent/CA2073060A1/en not_active Abandoned
- 1991-01-16 EP EP19910903736 patent/EP0511300A4/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988005824A1 (en) * | 1987-02-02 | 1988-08-11 | E.I. Du Pont De Nemours And Company | Selection of monoclonal antibodies to viral glycoproteins |
US4861707A (en) * | 1987-02-02 | 1989-08-29 | E. I. Du Pont De Nemours And Company | Human immunodeficiency virus antigen |
Non-Patent Citations (3)
Title |
---|
Cell, Volume 46, issued 1986, J.M. COFFIN, "Genetic Variation in AIDS viruses", pages 1-4, see paragraph bridging pages 1 and page 2, and page 3. * |
IMMUNOLOGY vol. 68, 1989, OXFORD,U.K. pages 325 - 331 OHLIN ET AL 'HUMAN MONOCLONAL ANTIBODIES AGAINST A RECOMBINANT HIV ENVELOPE ANTIGEN PRODUCED BY PRIMARY IN VITRO IMMUNIZATION.CHARACTERIZATION AND EPITOPE MAPPING' * |
See also references of WO9110742A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2073060A1 (en) | 1991-07-17 |
WO1991010742A1 (en) | 1991-07-25 |
JPH05506142A (en) | 1993-09-16 |
EP0511300A1 (en) | 1992-11-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19920717 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19930406 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE |
|
16A | New documents despatched to applicant after publication of the search report | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Withdrawal date: 19950201 |