EP0500776A4 - Poly(alkyl and alkenyl phosphate)s and their thiophosphate and selenophosphate derivatives as antiviral agents - Google Patents
Poly(alkyl and alkenyl phosphate)s and their thiophosphate and selenophosphate derivatives as antiviral agentsInfo
- Publication number
- EP0500776A4 EP0500776A4 EP19910900534 EP91900534A EP0500776A4 EP 0500776 A4 EP0500776 A4 EP 0500776A4 EP 19910900534 EP19910900534 EP 19910900534 EP 91900534 A EP91900534 A EP 91900534A EP 0500776 A4 EP0500776 A4 EP 0500776A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- selenophosphate
- thiophosphate
- poly
- derivatives
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/141—Esters of phosphorous acids
- C07F9/1411—Esters of phosphorous acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US438355 | 1982-11-01 | ||
US43835589A | 1989-11-17 | 1989-11-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0500776A1 EP0500776A1 (en) | 1992-09-02 |
EP0500776A4 true EP0500776A4 (en) | 1993-03-24 |
Family
ID=23740326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19910900534 Withdrawn EP0500776A4 (en) | 1989-11-17 | 1990-11-13 | Poly(alkyl and alkenyl phosphate)s and their thiophosphate and selenophosphate derivatives as antiviral agents |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0500776A4 (en) |
JP (1) | JPH05501709A (en) |
WO (1) | WO1991007092A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6057093A (en) * | 1992-09-28 | 2000-05-02 | Chiron Corporation | Methods and compositions for controlling translation of HCV proteins |
US5604097A (en) | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0288163A2 (en) * | 1987-03-25 | 1988-10-26 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Oligodeoxynucleotides as inhibitors of the replication of retroviruses and the expression of oncogenes |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4826823A (en) * | 1985-02-05 | 1989-05-02 | Warner-Lambert Company | Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts |
-
1990
- 1990-11-13 JP JP50105890A patent/JPH05501709A/en active Pending
- 1990-11-13 EP EP19910900534 patent/EP0500776A4/en not_active Withdrawn
- 1990-11-13 WO PCT/US1990/006630 patent/WO1991007092A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0288163A2 (en) * | 1987-03-25 | 1988-10-26 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Oligodeoxynucleotides as inhibitors of the replication of retroviruses and the expression of oncogenes |
Non-Patent Citations (4)
Title |
---|
JOURNAL OF CELLULAR BIOCHEMISTRY vol. SUPPL, no. 14D, March 1990, page 100 W. EGAN ET AL. 'SYNTHESIS AND EVALUATION OF ABASIC OLIGODESOXYRIBONUCLEOTIDE PHOSPHOROTHIOATES AS ANTI-HIV-1 AGENTS' * |
NUCLEIC ACIDS RESEARCH vol. 17, no. 20, 1989, pages 8207 - 8219 K. MORI ET AL. 'PHOSPHOROSELENOATE OLIGODEOXYNUCLEOTIDES: SYNTHESIS, PHYSICO-CHEMICAL CHARACTERIZATION, ANTI-SENSE INHIBITORY PROPERTIES AND ANTI-HIV ACTIVITY' * |
NUCLEIC ACIDS RESEARCH vol. 18, no. 10, 25 May 1990, pages 2855 - 2859 R.P. LYER ET AL. 'ABASIC OLIGODEOXYRIBONUCLEOTIDE PHOSPHOROTHIOATES: SYNTHESIS AND EVALUATION AS ANTI-HIV-1 AGENTS' * |
See also references of WO9107092A1 * |
Also Published As
Publication number | Publication date |
---|---|
JPH05501709A (en) | 1993-04-02 |
WO1991007092A1 (en) | 1991-05-30 |
EP0500776A1 (en) | 1992-09-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19920612 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19930202 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19941222 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: LYNX THERAPEUTICS, INC. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19960423 |