EP0491792A4 - Methods of treating neurodegenerative conditions - Google Patents

Methods of treating neurodegenerative conditions

Info

Publication number
EP0491792A4
EP0491792A4 EP19900913759 EP90913759A EP0491792A4 EP 0491792 A4 EP0491792 A4 EP 0491792A4 EP 19900913759 EP19900913759 EP 19900913759 EP 90913759 A EP90913759 A EP 90913759A EP 0491792 A4 EP0491792 A4 EP 0491792A4
Authority
EP
European Patent Office
Prior art keywords
methods
treating neurodegenerative
neurodegenerative conditions
conditions
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900913759
Other versions
EP0491792A1 (en
Inventor
Paul Marangos
Harry Gruber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sicor Inc
Original Assignee
Sicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Inc filed Critical Sicor Inc
Publication of EP0491792A1 publication Critical patent/EP0491792A1/en
Publication of EP0491792A4 publication Critical patent/EP0491792A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Treatment Of Fiber Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19900913759 1989-09-15 1990-09-12 Methods of treating neurodegenerative conditions Withdrawn EP0491792A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40791389A 1989-09-15 1989-09-15
US407913 1989-09-15

Publications (2)

Publication Number Publication Date
EP0491792A1 EP0491792A1 (en) 1992-07-01
EP0491792A4 true EP0491792A4 (en) 1992-12-02

Family

ID=23614067

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900913759 Withdrawn EP0491792A4 (en) 1989-09-15 1990-09-12 Methods of treating neurodegenerative conditions

Country Status (6)

Country Link
EP (1) EP0491792A4 (en)
JP (1) JPH05506842A (en)
KR (1) KR920703068A (en)
AU (1) AU643235B2 (en)
NO (1) NO920983L (en)
WO (1) WO1991004032A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE206755T1 (en) * 1991-08-09 2001-10-15 Massachusetts Inst Technology USES OF A PROTEIN KINASE OF CLAY AND NEUROFILAMENT PK40
DK62592D0 (en) * 1992-05-14 1992-05-14 Novo Nordisk As
EP0582164B1 (en) * 1992-07-31 1998-12-23 Bristol-Myers Squibb Company Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles
US5589467A (en) * 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
US5780450A (en) * 1995-11-21 1998-07-14 Alcon Laboratories, Inc. Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
DE19707655A1 (en) * 1997-02-26 1998-08-27 Hoechst Ag Combination preparation for use in dementia
US6440455B1 (en) * 1997-09-02 2002-08-27 Children's Medical Center Corporation Methods for modulating the axonal outgrowth of central nervous system neurons

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0301900A2 (en) * 1987-07-29 1989-02-01 The Regents Of The University Of California L'utilisation de riboside ou ribotide de l'AICA pour la fabrication d'un médicament contre la crise cardiaque ou l'infarctus du myocarde aux patients souffrant d'athérosclerosis.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4575498A (en) * 1983-07-21 1986-03-11 Duke University Method for restoring depleted purine nucleotide pools

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0301900A2 (en) * 1987-07-29 1989-02-01 The Regents Of The University Of California L'utilisation de riboside ou ribotide de l'AICA pour la fabrication d'un médicament contre la crise cardiaque ou l'infarctus du myocarde aux patients souffrant d'athérosclerosis.

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRAIN RESEARCH BULLETIN, vol. 25, no. 1, 1990, pages 203-206, Pergamon Press plc, US; C. CLOUGH-HELFMAN et al.: "5-Aminoimidazole-4-carboxamide riboside (AICAr) administration reduced cerebral ischemic damage in the mongolian gerbil" *
EPILEPSIA, vol. 31, no. 3, 1990, pages 239-246; P.J. MARANGOS et al.: "Adenosinergic modulation of homocysteine-induced seizures in mice" *
LIFE SCIENCES, vol. 42, no. 14, 1988, pages 1331-1345, Pergamon Press, US; J. DECKERT et al.: "Adenosine uptake site heterogeneity in the mammalian CNS? uptake inhibitors as probes and potential neuropharmaceuticals" *
See also references of WO9104032A1 *

Also Published As

Publication number Publication date
NO920983D0 (en) 1992-03-13
AU6401590A (en) 1991-04-18
EP0491792A1 (en) 1992-07-01
JPH05506842A (en) 1993-10-07
WO1991004032A1 (en) 1991-04-04
NO920983L (en) 1992-03-13
AU643235B2 (en) 1993-11-11
KR920703068A (en) 1992-12-17

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19920326

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

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Effective date: 19950120

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Owner name: GENSIA, INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19960828