EP0469042A4 - Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof - Google Patents

Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof

Info

Publication number
EP0469042A4
EP0469042A4 EP19900906714 EP90906714A EP0469042A4 EP 0469042 A4 EP0469042 A4 EP 0469042A4 EP 19900906714 EP19900906714 EP 19900906714 EP 90906714 A EP90906714 A EP 90906714A EP 0469042 A4 EP0469042 A4 EP 0469042A4
Authority
EP
European Patent Office
Prior art keywords
oligodeoxynucleotides
novel
production
chemical groups
linked chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900906714
Other versions
EP0469042A1 (en
Inventor
Jack S. Cohen
Kenya Mori
Makoto Matsukura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
US Department of Commerce
Original Assignee
US Department of Health and Human Services
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, US Department of Commerce filed Critical US Department of Health and Human Services
Publication of EP0469042A1 publication Critical patent/EP0469042A1/en
Publication of EP0469042A4 publication Critical patent/EP0469042A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19900906714 1989-04-18 1990-03-23 Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof Withdrawn EP0469042A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34007389A 1989-04-18 1989-04-18
US340073 1989-04-18

Publications (2)

Publication Number Publication Date
EP0469042A1 EP0469042A1 (en) 1992-02-05
EP0469042A4 true EP0469042A4 (en) 1992-07-01

Family

ID=23331752

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900906714 Withdrawn EP0469042A4 (en) 1989-04-18 1990-03-23 Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof

Country Status (5)

Country Link
EP (1) EP0469042A4 (en)
JP (1) JPH04500679A (en)
AU (1) AU633911B2 (en)
CA (1) CA2049361A1 (en)
WO (1) WO1990012802A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733523A (en) * 1990-12-10 1998-03-31 Akzo Nobel N.V. Targeted delivery of a therapeutic entity using complementary oligonucleotides
IE914220A1 (en) * 1990-12-10 1992-06-17 Akzo Nv Labelled, modified oligonucleotides
ATE254624T1 (en) * 1999-07-07 2003-12-15 Exiqon As SYNTHESIS OF STABLE CHINONE AND PHOTOREACTIVE KETONE PHOSPHORAMIDITE REAGENT FOR SOLID PHASE SYNTHESIS OF PHOTOREACTIVE OLIGOMER CONJUGATES
US6531591B1 (en) 1999-07-07 2003-03-11 Exiqon A/S Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2227867A1 (en) * 1973-05-02 1974-11-29 Farmaceutici Italia
WO1990003383A1 (en) * 1988-09-20 1990-04-05 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Phosphorothioate and normal oligodeoxynucleotides with 5'-linked acridine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687808A (en) * 1969-08-14 1972-08-29 Univ Leland Stanford Junior Synthetic polynucleotides
AU5418290A (en) * 1989-03-31 1990-11-05 University Patents Inc. Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections
AU6603690A (en) * 1989-10-05 1991-04-28 University Patents Inc. Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2227867A1 (en) * 1973-05-02 1974-11-29 Farmaceutici Italia
WO1990003383A1 (en) * 1988-09-20 1990-04-05 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Phosphorothioate and normal oligodeoxynucleotides with 5'-linked acridine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF MEDICINAL CHEMISTRY, vol. 25, no. 4, April 1982, pages 369-373; S. BENNETT et al.: "Preparation and evaluation of 2-substituted anthraquinones based on the anthracyclines" *
See also references of WO9012802A1 *

Also Published As

Publication number Publication date
JPH04500679A (en) 1992-02-06
CA2049361A1 (en) 1990-10-19
WO1990012802A1 (en) 1990-11-01
EP0469042A1 (en) 1992-02-05
AU5526390A (en) 1990-11-16
AU633911B2 (en) 1993-02-11

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: MATSUKURA, MAKOTO, C/O CHILD DEVELOPMENT

Inventor name: COHEN, JACK, S.

Inventor name: MORI, KENYA, C/O YAMASA SHOYU COMPANY

17Q First examination report despatched

Effective date: 19941206

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19980101