EP0467965A4 - Plasmodium circumsporozoite protein analogs lacking repeat sequences - Google Patents

Plasmodium circumsporozoite protein analogs lacking repeat sequences

Info

Publication number
EP0467965A4
EP0467965A4 EP19900906626 EP90906626A EP0467965A4 EP 0467965 A4 EP0467965 A4 EP 0467965A4 EP 19900906626 EP19900906626 EP 19900906626 EP 90906626 A EP90906626 A EP 90906626A EP 0467965 A4 EP0467965 A4 EP 0467965A4
Authority
EP
European Patent Office
Prior art keywords
repeat sequences
circumsporozoite protein
protein analogs
analogs lacking
plasmodium circumsporozoite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19900906626
Other versions
EP0467965A1 (en
Inventor
Philip J. Barr
Ian C. Bathurst
Helen L. Gibson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of EP0467965A1 publication Critical patent/EP0467965A1/en
Publication of EP0467965A4 publication Critical patent/EP0467965A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19900906626 1989-04-11 1990-04-11 Plasmodium circumsporozoite protein analogs lacking repeat sequences Pending EP0467965A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33628889A 1989-04-11 1989-04-11
US336288 1989-04-11

Publications (2)

Publication Number Publication Date
EP0467965A1 EP0467965A1 (en) 1992-01-29
EP0467965A4 true EP0467965A4 (en) 1992-04-15

Family

ID=23315419

Family Applications (2)

Application Number Title Priority Date Filing Date
EP19900906626 Pending EP0467965A4 (en) 1989-04-11 1990-04-11 Plasmodium circumsporozoite protein analogs lacking repeat sequences
EP19900303907 Withdrawn EP0392820A3 (en) 1989-04-11 1990-04-11 Plasmodium circumsporozoite protein analogs lacking repeat sequences

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP19900303907 Withdrawn EP0392820A3 (en) 1989-04-11 1990-04-11 Plasmodium circumsporozoite protein analogs lacking repeat sequences

Country Status (10)

Country Link
EP (2) EP0467965A4 (en)
JP (1) JPH04506064A (en)
AP (1) AP134A (en)
AU (1) AU635265B2 (en)
CA (1) CA2051432A1 (en)
IL (1) IL94063A0 (en)
NZ (1) NZ233255A (en)
PT (1) PT93721A (en)
WO (1) WO1990011775A1 (en)
ZA (1) ZA902741B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362623A (en) * 1991-06-14 1994-11-08 The John Hopkins University Sequence specific DNA binding by p53
DE19544233A1 (en) * 1995-11-28 1997-06-05 Hoechst Ag Process for using the yeast ADH II promoter system for the biotechnological production of heterologous proteins in high yields
CA2593643C (en) 2005-01-18 2016-03-22 Walter Reed Army Institute Of Research A plasmodium vivax hybrid circumsporozoite protein and vaccine
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166410A2 (en) * 1984-06-26 1986-01-02 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
EP0192626A1 (en) * 1985-02-07 1986-08-27 Smithkline Beecham Corporation Malaria vaccine
WO1987000533A1 (en) * 1985-07-12 1987-01-29 New York University Immunogenic peptide antigen corresponding to plasmodium vivax circumsporozoite protein
EP0254862A1 (en) * 1986-06-26 1988-02-03 BEHRINGWERKE Aktiengesellschaft Vaccines against protozoan parasites
WO1988007546A1 (en) * 1987-03-30 1988-10-06 New York University Immunogenic polypeptide and method for purifying it
EP0398540A1 (en) * 1989-05-03 1990-11-22 Smithkline Beecham Corporation Malaria vaccine
EP0432965A1 (en) * 1989-12-08 1991-06-19 Smithkline Beecham Corporation Malaria vaccine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329124C (en) * 1987-02-02 1994-05-03 Jerald C. Sadoff Conjugate malaria vaccine
IT1223301B (en) * 1987-09-11 1990-09-19 Eniricerche Spa IMMUNOLOGICALLY ACTIVE SEQUENTIAL POLYPEPTIDES
US5112749A (en) * 1987-10-02 1992-05-12 Praxis Biologics, Inc. Vaccines for the malaria circumsporozoite protein

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166410A2 (en) * 1984-06-26 1986-01-02 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
EP0192626A1 (en) * 1985-02-07 1986-08-27 Smithkline Beecham Corporation Malaria vaccine
WO1987000533A1 (en) * 1985-07-12 1987-01-29 New York University Immunogenic peptide antigen corresponding to plasmodium vivax circumsporozoite protein
EP0254862A1 (en) * 1986-06-26 1988-02-03 BEHRINGWERKE Aktiengesellschaft Vaccines against protozoan parasites
WO1988007546A1 (en) * 1987-03-30 1988-10-06 New York University Immunogenic polypeptide and method for purifying it
EP0398540A1 (en) * 1989-05-03 1990-11-22 Smithkline Beecham Corporation Malaria vaccine
EP0432965A1 (en) * 1989-12-08 1991-06-19 Smithkline Beecham Corporation Malaria vaccine

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BIOTECHNOLOGY ABSTRACTS DATABASE accession no. 89-05065; P.J. ROMERO et al.: "Multiple T helper cell epitopes of the circumsporozoite protein of plasmodium berghei - Recombinant vaccine preparation; gene cloning and expression in saccharomyces cerevisiae" & Eur.J.Immunol. 1988, vol.18, no. 12, pages 1951-1957 *
See also references of WO9011775A1 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY vol. 262, no. 25, 5 September 1987, pages 11935-11939, Baltimore, MD, US; V.F: DE LA CRUZ et al.: "Sequence Variation in Putative Functional Domains of the Circumsporozoite Protein of Plasmodium falciparum" *
TRENDS IN BIOTECHNOLOGY vol. 6, no. 3, March 1988, pages 63-68, Cambridge, GB; J.F. YOUNG et al.: "The prospects for a human malaria vaccine" *

Also Published As

Publication number Publication date
AU5524290A (en) 1990-11-05
AU635265B2 (en) 1993-03-18
ZA902741B (en) 1991-03-27
EP0392820A3 (en) 1990-12-27
AP9000176A0 (en) 1990-04-30
AP134A (en) 1991-07-16
PT93721A (en) 1990-11-20
WO1990011775A1 (en) 1990-10-18
JPH04506064A (en) 1992-10-22
EP0392820A2 (en) 1990-10-17
EP0467965A1 (en) 1992-01-29
NZ233255A (en) 1993-02-25
IL94063A0 (en) 1991-01-31
CA2051432A1 (en) 1990-10-12

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Legal Events

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Inventor name: GIBSON, HELEN, L.

Inventor name: BARR, PHILIP, J.

Inventor name: BATHURST, IAN, C.

A4 Supplementary search report drawn up and despatched

Effective date: 19920226

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Free format text: VERFAHREN ABGESCHLOSSEN INFOLGE VERBINDUNG MIT 90303907.1/0392820 (EUROPAEISCHE ANMELDENUMMER/VEROEFFENTLICHUNGSNUMMER) VOM 14.09.92.