EP0409923A4 - Expression of the i(plasmodium) circumsporozoite protein in insect cells - Google Patents

Expression of the i(plasmodium) circumsporozoite protein in insect cells

Info

Publication number
EP0409923A4
EP0409923A4 EP19900900688 EP90900688A EP0409923A4 EP 0409923 A4 EP0409923 A4 EP 0409923A4 EP 19900900688 EP19900900688 EP 19900900688 EP 90900688 A EP90900688 A EP 90900688A EP 0409923 A4 EP0409923 A4 EP 0409923A4
Authority
EP
European Patent Office
Prior art keywords
plasmodium
expression
insect cells
circumsporozoite protein
circumsporozoite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900900688
Other versions
EP0409923A1 (en
Inventor
Alex Bollen
Pascal Gilles
Michel Heinderyckx
Paul Jacobs
Hanne Ranch Johansen
Marc Massaer
Martin Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Biological SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Biological SA filed Critical SmithKline Biological SA
Publication of EP0409923A1 publication Critical patent/EP0409923A1/en
Publication of EP0409923A4 publication Critical patent/EP0409923A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/866—Baculoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP19900900688 1988-12-21 1989-12-13 Expression of the i(plasmodium) circumsporozoite protein in insect cells Withdrawn EP0409923A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28793488A 1988-12-21 1988-12-21
US287934 1988-12-21

Publications (2)

Publication Number Publication Date
EP0409923A1 EP0409923A1 (en) 1991-01-30
EP0409923A4 true EP0409923A4 (en) 1993-01-20

Family

ID=23105005

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900900688 Withdrawn EP0409923A4 (en) 1988-12-21 1989-12-13 Expression of the i(plasmodium) circumsporozoite protein in insect cells

Country Status (11)

Country Link
EP (1) EP0409923A4 (en)
JP (1) JPH03504082A (en)
KR (1) KR910700352A (en)
AU (1) AU634512B2 (en)
CA (1) CA2005512A1 (en)
DK (1) DK187790D0 (en)
IL (1) IL92782A0 (en)
NZ (1) NZ231795A (en)
PT (1) PT92677A (en)
WO (1) WO1990007006A1 (en)
ZA (1) ZA899610B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2003794C (en) * 1988-12-01 2000-02-08 Hanne R. Johansen Expression of hiv proteins in drosophila cells
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166410A2 (en) * 1984-06-26 1986-01-02 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
EP0278941A1 (en) * 1987-01-30 1988-08-17 Smithkline Biologicals S.A. Expression of the P. falciparum circumsporozoite protein by yeast
EP0290261A1 (en) * 1987-05-08 1988-11-09 Smithkline Beecham Corporation Expression of foreign genes in drosophila cells

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745051A (en) * 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166410A2 (en) * 1984-06-26 1986-01-02 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
EP0278941A1 (en) * 1987-01-30 1988-08-17 Smithkline Biologicals S.A. Expression of the P. falciparum circumsporozoite protein by yeast
EP0290261A1 (en) * 1987-05-08 1988-11-09 Smithkline Beecham Corporation Expression of foreign genes in drosophila cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MOL. BIOL. MED., vol. 5, 1988, pages 185-196, Academic Press Ltd; F. DONTFRAID et al.: "Human and murine CD4 T cell epitopes map to the same region of the malaria circumsporozoite protein: limited immunogenicity of sporozoites and circumsporozoite protein" *
MOLECULAR AND CELLULAR BIOLOGY, vol. 6, no. 6, June 1986, pages 2080-2088; American Society for Microbiology, US; B.J. BOND et al.: "The Drosophilia melanogaster Actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species" *
See also references of WO9007006A1 *

Also Published As

Publication number Publication date
KR910700352A (en) 1991-03-14
ZA899610B (en) 1990-11-28
DK187790A (en) 1990-08-06
PT92677A (en) 1990-06-29
EP0409923A1 (en) 1991-01-30
AU634512B2 (en) 1993-02-25
CA2005512A1 (en) 1990-06-21
IL92782A0 (en) 1990-09-17
AU4803790A (en) 1990-07-10
JPH03504082A (en) 1991-09-12
DK187790D0 (en) 1990-08-06
WO1990007006A1 (en) 1990-06-28
NZ231795A (en) 1992-04-28

Similar Documents

Publication Publication Date Title
IT1224421B (en) MODIFIED GALATTOMANNANS AND REALIVE PREPARATION PROCEDURE
ITTO910001A1 (en) IMPROVED METHOD TO PRODUCE COFFEE EXTRACTS
GB8907148D0 (en) Biologically active proteins
HUT45558A (en) Increased expressing human-interleukin 2 in mammalian celles
GB8721015D0 (en) Modifying living cells
EP0362758A3 (en) Electro-insertion of proteins into animal cell membranes
FR2628838B1 (en) ELECTRICALLY PRODUCED LUMINESCENCE IN SOLUTION
EP0372056A4 (en) Protein micelles
IL91335A0 (en) Dna sequence and hepadnavirus
IL88948A0 (en) Truss structure
EP0409923A4 (en) Expression of the i(plasmodium) circumsporozoite protein in insect cells
ZA895461B (en) Modified proteins
KR900004691A (en) Phenylpyridine and preparation method thereof
PL278779A1 (en) Artificial heart
GB8816095D0 (en) Protein
IL92470A0 (en) Expression of hiv proteins in drosophila cells
IE894106L (en) Expression of the plasmodium circumsporozite protein in¹insects
GB2223775B (en) Shelter
KR900008593A (en) Direct-cathode cathode structure
GB9001044D0 (en) Rasteny substituted phenylalkylformamines and fungicidal preparation based thereon
IE880272L (en) Protein extracts
IE883848L (en) Human b lympoblastoid cell
IE893992L (en) Potentiating natural killer cell activity
IE893803L (en) Expression of hiv proteins in drosophila cells
BR6801895U (en) PROVISION INTRODUCED IN PROSTHESIS

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19900810

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19921201

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17Q First examination report despatched

Effective date: 19930210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930821