EP0386002A4 - Gene transfer for drug resistance - Google Patents

Gene transfer for drug resistance

Info

Publication number
EP0386002A4
EP0386002A4 EP19880906678 EP88906678A EP0386002A4 EP 0386002 A4 EP0386002 A4 EP 0386002A4 EP 19880906678 EP19880906678 EP 19880906678 EP 88906678 A EP88906678 A EP 88906678A EP 0386002 A4 EP0386002 A4 EP 0386002A4
Authority
EP
European Patent Office
Prior art keywords
gene transfer
drug resistance
drug
resistance
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19880906678
Other versions
EP0386002A1 (en
Inventor
Stephen Barnard Howell
Inder Verma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Development Foundation
Original Assignee
Clayton Foundation for Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clayton Foundation for Research filed Critical Clayton Foundation for Research
Publication of EP0386002A1 publication Critical patent/EP0386002A1/en
Publication of EP0386002A4 publication Critical patent/EP0386002A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
EP19880906678 1987-05-28 1988-05-26 Gene transfer for drug resistance Withdrawn EP0386002A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712528A GB8712528D0 (en) 1987-05-28 1987-05-28 Gene transfer
GB8712528 1987-05-28

Publications (2)

Publication Number Publication Date
EP0386002A1 EP0386002A1 (en) 1990-09-12
EP0386002A4 true EP0386002A4 (en) 1990-09-26

Family

ID=10618026

Family Applications (2)

Application Number Title Priority Date Filing Date
EP19880906678 Withdrawn EP0386002A4 (en) 1987-05-28 1988-05-26 Gene transfer for drug resistance
EP19880304759 Pending EP0293193A3 (en) 1987-05-28 1988-05-26 Gene transfer for drug resistance

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP19880304759 Pending EP0293193A3 (en) 1987-05-28 1988-05-26 Gene transfer for drug resistance

Country Status (11)

Country Link
EP (2) EP0386002A4 (en)
JP (1) JPH02503512A (en)
AU (1) AU618749B2 (en)
DK (1) DK34489D0 (en)
FI (1) FI894851A0 (en)
GB (1) GB8712528D0 (en)
IL (1) IL86532A0 (en)
NZ (1) NZ224802A (en)
PT (1) PT87597B (en)
WO (1) WO1988009383A1 (en)
ZA (1) ZA883804B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6337209B1 (en) 1992-02-26 2002-01-08 Glaxo Wellcome Inc. Molecular constructs containing a carcinoembryonic antigen regulatory sequence
GB8919607D0 (en) * 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
US6770274B1 (en) * 1990-09-14 2004-08-03 The General Hospital Corporation Viral mutant HSV mediated destruction of neoplastic cells
CA2051289C (en) * 1990-09-14 2002-11-26 Robert L. Martuza Viral mediated destruction of neoplastic cells
US6555370B1 (en) 1990-11-13 2003-04-29 Immunex Corporation Bifunctional selectable fusion genes
AU650085B2 (en) * 1990-11-13 1994-06-09 Immunex Corporation Bifunctional selectable fusion genes
DE4444949C1 (en) * 1994-12-16 1996-11-21 Deutsches Krebsforsch Vectors and viruses for gene therapy
US9023031B2 (en) 1997-08-13 2015-05-05 Verathon Inc. Noninvasive devices, methods, and systems for modifying tissues
US7306591B2 (en) 2000-10-02 2007-12-11 Novasys Medical, Inc. Apparatus and methods for treating female urinary incontinence

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000922A1 (en) * 1984-07-30 1986-02-13 The Salk Institute For Biological Studies Retroviral gene transfer vectors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000922A1 (en) * 1984-07-30 1986-02-13 The Salk Institute For Biological Studies Retroviral gene transfer vectors

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS, vol. 83, 1987, abstract no. 85881, Biological Abstracts, Inc., Philadelphia, PA, US; S.M.W. CHANG et al.: "Construction of a defective retrovirus containing the human hypoxanthine phosphoribosyltransferase complementary DNA and its expression in cultured cells and mouse bone marrow", & MOL. CELL. BIOL. 7(2): 854-863, 1987 *
BIOTECHNOLOGY, vol. 3, no. 3, August 1985, pages 689-693, New York, US; D. McCORMICK: "Human gene therapy: The first round" *
MOL. BIOL. MED., vol. 4, 1987, pages 157-168, Academic Press, Inc., London, GB; S.B. HOWELL et al.: "Gene therapy for thioguanine-resistant human leukemia" *
MOLECULAR AND CELLULAR BIOLOGY, vol. 7, no. 5, May 1987, pages 1797-1806, American Society for microbiology; R.A. BOSSELMAN et al.: "Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: Expression of moloney murine leukemia virus structural genes via the metallothionein promoter" *
See also references of WO8809383A1 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 259, no. 12, 25th June 1984, pages 7842-7849, the American Society of Biological Chemists, Inc., US; R.C. WILLIS et al.: "Partial phenotypic correction of human lesch-nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector" *

Also Published As

Publication number Publication date
NZ224802A (en) 1991-01-29
EP0386002A1 (en) 1990-09-12
ZA883804B (en) 1990-08-29
JPH02503512A (en) 1990-10-25
WO1988009383A1 (en) 1988-12-01
AU2125388A (en) 1988-12-21
FI894851A0 (en) 1989-10-13
EP0293193A3 (en) 1990-09-12
IL86532A0 (en) 1988-11-15
GB8712528D0 (en) 1987-07-01
DK34489A (en) 1989-01-26
AU618749B2 (en) 1992-01-09
DK34489D0 (en) 1989-01-26
PT87597A (en) 1988-06-01
EP0293193A2 (en) 1988-11-30
PT87597B (en) 1992-09-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19891021

AK Designated contracting states

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Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19900809

AK Designated contracting states

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: RESEARCH DEVELOPMENT FOUNDATION

XX Miscellaneous (additional remarks)

Free format text: VERBUNDEN MIT 88304759.9/0293193 (EUROPAEISCHE ANMELDENUMMER/VEROEFFENTLICHUNGSNUMMER) DURCH ENTSCHEIDUNG VOM 23.09.91.

17Q First examination report despatched

Effective date: 19920114

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19920725