EP0380592A4 - 2-oxo-1-substituted pyrazolo 1,5-a¨pyrimidine-6-carboxylic acid esters - Google Patents

2-oxo-1-substituted pyrazolo 1,5-a¨pyrimidine-6-carboxylic acid esters

Info

Publication number
EP0380592A4
EP0380592A4 EP19890901760 EP89901760A EP0380592A4 EP 0380592 A4 EP0380592 A4 EP 0380592A4 EP 19890901760 EP19890901760 EP 19890901760 EP 89901760 A EP89901760 A EP 89901760A EP 0380592 A4 EP0380592 A4 EP 0380592A4
Authority
EP
European Patent Office
Prior art keywords
pyrimidine
oxo
carboxylic acid
acid esters
substituted pyrazolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19890901760
Other versions
EP0380592A1 (en
Inventor
Karnail Atwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/145,007 external-priority patent/US4870072A/en
Priority claimed from US07/145,004 external-priority patent/US4859676A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of EP0380592A1 publication Critical patent/EP0380592A1/en
Publication of EP0380592A4 publication Critical patent/EP0380592A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19890901760 1988-01-19 1989-01-05 2-oxo-1-substituted pyrazolo 1,5-a¨pyrimidine-6-carboxylic acid esters Ceased EP0380592A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US145004 1988-01-19
US145007 1988-01-19
US07/145,007 US4870072A (en) 1988-01-19 1988-01-19 2-oxo-1-substituted pyrazolo[1,5-A]pyrimidine-6-carboxylic acid esters as blood pressure reducing agents
US07/145,004 US4859676A (en) 1988-01-19 1988-01-19 2-Oxo-1-sulfonyl pyrazolo(1,5-a) pyrimidine-6-carboxylic acid esters

Publications (2)

Publication Number Publication Date
EP0380592A1 EP0380592A1 (en) 1990-08-08
EP0380592A4 true EP0380592A4 (en) 1991-10-09

Family

ID=26842566

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890901760 Ceased EP0380592A4 (en) 1988-01-19 1989-01-05 2-oxo-1-substituted pyrazolo 1,5-a¨pyrimidine-6-carboxylic acid esters

Country Status (2)

Country Link
EP (1) EP0380592A4 (en)
WO (1) WO1989006535A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) * 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
JP2003529552A (en) * 1999-11-19 2003-10-07 アボット・ラボラトリーズ Tricyclic dihydropyrimidine potassium channel opener
US6538000B1 (en) 1999-11-19 2003-03-25 Abbott Laboratories Tricyclic dihydropyrimidine potassium channel openers

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0204317A2 (en) * 1985-06-03 1986-12-10 E.R. Squibb & Sons, Inc. 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters
EP0217142A2 (en) * 1985-09-30 1987-04-08 Yoshitomi Pharmaceutical Industries, Ltd. A polyazaheterocyclic compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2593890A (en) * 1948-08-11 1952-04-22 Gen Aniline & Film Corp 3, 3'-bis
US4746656A (en) * 1986-07-21 1988-05-24 E. R. Squibb & Sons, Inc. 1,2,4,7-tetrahydro-2-oxopyrazolo[1,5-a]pyrimidine derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0204317A2 (en) * 1985-06-03 1986-12-10 E.R. Squibb & Sons, Inc. 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters
EP0217142A2 (en) * 1985-09-30 1987-04-08 Yoshitomi Pharmaceutical Industries, Ltd. A polyazaheterocyclic compound

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8906535A1 *

Also Published As

Publication number Publication date
WO1989006535A1 (en) 1989-07-27
EP0380592A1 (en) 1990-08-08

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Free format text: 2-OXO-1-SUBSTITUTED PYRAZOLO??1,5-A PYRIMIDINE-6-CARBOXYLIC ACID ESTERS