EP0365656A4 - Prophylactic and therapeutic methods for treating edema with phallotoxins - Google Patents

Prophylactic and therapeutic methods for treating edema with phallotoxins

Info

Publication number
EP0365656A4
EP0365656A4 EP19890905296 EP89905296A EP0365656A4 EP 0365656 A4 EP0365656 A4 EP 0365656A4 EP 19890905296 EP19890905296 EP 19890905296 EP 89905296 A EP89905296 A EP 89905296A EP 0365656 A4 EP0365656 A4 EP 0365656A4
Authority
EP
European Patent Office
Prior art keywords
phallotoxins
prophylactic
therapeutic methods
treating edema
edema
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890905296
Other versions
EP0365656A1 (en
Inventor
David Shepro
J. Steven Alexander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston University
Original Assignee
Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston University filed Critical Boston University
Publication of EP0365656A1 publication Critical patent/EP0365656A1/en
Publication of EP0365656A4 publication Critical patent/EP0365656A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19890905296 1988-04-25 1989-04-25 Prophylactic and therapeutic methods for treating edema with phallotoxins Withdrawn EP0365656A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18565088A 1988-04-25 1988-04-25
US185650 2002-06-27

Publications (2)

Publication Number Publication Date
EP0365656A1 EP0365656A1 (en) 1990-05-02
EP0365656A4 true EP0365656A4 (en) 1990-12-05

Family

ID=22681884

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890905296 Withdrawn EP0365656A4 (en) 1988-04-25 1989-04-25 Prophylactic and therapeutic methods for treating edema with phallotoxins

Country Status (4)

Country Link
EP (1) EP0365656A4 (en)
JP (1) JPH02501577A (en)
AU (1) AU3539189A (en)
WO (1) WO1989010136A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998031380A1 (en) * 1997-01-16 1998-07-23 Washington State University Research Foundation Phalloidin derivatives and analogs to treat congestive heart failure
US20120231996A1 (en) * 2006-05-04 2012-09-13 Lokey R Scott Phalloidin derivatives and methods for their synthesis
CN109824785B (en) * 2019-02-28 2021-03-23 中国农业大学 Dihydroxyl phalloidin artificial antigen and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4387088A (en) * 1980-02-25 1983-06-07 Cornell Research Foundation, Inc. NBD-Acidic phallotoxins and their use in the fluorescence staining of F-actin
US4489001A (en) * 1980-02-25 1984-12-18 Cornell Research Foundation, Inc. Acidic phallotoxin derivatives and methods of preparation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MICROVASCULAR RESEARCH, vol. 35, no. 3, 1988, pages 308-315, Academic Press, Inc.; J.S. ALEXANDER et al.: "Phalloidin enhances endothelial barrier function and reduces inflammatory permeability in vitro" *
See also references of WO8910136A1 *
THE FASEB JOURNAL - 72nd Annual Meeting Federation of American Societies for Experimental Biology, Las Vegas, 1st - 5th May 1988, vol. 2, no. 6, 25th March 1988, page A1856, US; J.S. ALEXANDER et al.: "Phalloidin enhances endothelial barrier function and reduces inflammatory permeability in vitro" *

Also Published As

Publication number Publication date
AU3539189A (en) 1989-11-24
EP0365656A1 (en) 1990-05-02
JPH02501577A (en) 1990-05-31
WO1989010136A1 (en) 1989-11-02

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Legal Events

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