EP0362359A4 - Antiviral composition containing aromatic polycyclic diones and nucleoside analogs and method for treating retrovirus infections - Google Patents

Antiviral composition containing aromatic polycyclic diones and nucleoside analogs and method for treating retrovirus infections

Info

Publication number
EP0362359A4
EP0362359A4 EP19890904668 EP89904668A EP0362359A4 EP 0362359 A4 EP0362359 A4 EP 0362359A4 EP 19890904668 EP19890904668 EP 19890904668 EP 89904668 A EP89904668 A EP 89904668A EP 0362359 A4 EP0362359 A4 EP 0362359A4
Authority
EP
European Patent Office
Prior art keywords
composition containing
containing aromatic
nucleoside analogs
antiviral composition
aromatic polycyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890904668
Other languages
English (en)
Other versions
EP0362359A1 (fr
Inventor
Daniel Meruelo
Gad Lavie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
Original Assignee
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University NYU filed Critical New York University NYU
Publication of EP0362359A1 publication Critical patent/EP0362359A1/fr
Publication of EP0362359A4 publication Critical patent/EP0362359A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EP19890904668 1988-03-23 1989-03-22 Antiviral composition containing aromatic polycyclic diones and nucleoside analogs and method for treating retrovirus infections Withdrawn EP0362359A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US17206488A 1988-03-23 1988-03-23
US172064 1988-03-23
US32417789A 1989-03-16 1989-03-16
US324177 1989-03-16
US32639289A 1989-03-20 1989-03-20
US326392 1989-03-20

Publications (2)

Publication Number Publication Date
EP0362359A1 EP0362359A1 (fr) 1990-04-11
EP0362359A4 true EP0362359A4 (en) 1991-11-21

Family

ID=27390073

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890904668 Withdrawn EP0362359A4 (en) 1988-03-23 1989-03-22 Antiviral composition containing aromatic polycyclic diones and nucleoside analogs and method for treating retrovirus infections

Country Status (4)

Country Link
EP (1) EP0362359A4 (fr)
AU (1) AU3423989A (fr)
DK (1) DK586989A (fr)
WO (1) WO1989009056A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0332679B1 (fr) * 1987-08-10 1993-06-16 New York University Compositions antivirales contenant des diones polycycliques aromatiques et procede de traitement d'infections par un retrovirus
CZ285232B6 (cs) * 1991-05-16 1999-06-16 Glaxo Group Limited Protivirové směsi
DE19547317A1 (de) * 1995-12-18 1998-12-24 Dreluso Pharm Dr Elten & Sohn Antivirales Medikament
US6607754B1 (en) * 1997-07-11 2003-08-19 Upsher-Smith Laboratories, Inc. Delivery of Hypericum perforatum (St. John's Wort) in tablet form

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989001329A1 (fr) * 1987-08-10 1989-02-23 New York University Compositions antivirales contenant des diones polycycliques aromatiques et procede de traitement d'infections par un retrovirus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
IL79661A (en) * 1986-08-08 1991-01-31 Yeda Res & Dev Antiviral composition containing hypericin or pseudohypericin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989001329A1 (fr) * 1987-08-10 1989-02-23 New York University Compositions antivirales contenant des diones polycycliques aromatiques et procede de traitement d'infections par un retrovirus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 85, no. 25, 20th December 1976, page87, abstract no. 187161z, Columbus, Ohio, US; E.L. MISHENKOVA et al.: "Antiiral properties of St. John's wort and prepaations produced from it", & TR. S'EDA MIKROBIOL. UKR., 4th 1975, 222-3 *
PROC. NATL. ACAD. SCI., vol. 85, Julz 1988, pages 5230-5234; D. MERUELO et al.: "Therapeutic agents with dramatic antiretroviral actiitu and little toxicitz at effectie doses: Aromatic polzcuclic diones hzpericin and Pseudohupericin" *
See also references of WO8909056A1 *

Also Published As

Publication number Publication date
DK586989A (da) 1990-01-19
DK586989D0 (da) 1989-11-22
AU3423989A (en) 1989-10-16
EP0362359A1 (fr) 1990-04-11
WO1989009056A1 (fr) 1989-10-05

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Legal Events

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