EP0333912A3 - Method for the evaporation of a sample - Google Patents

Method for the evaporation of a sample Download PDF

Info

Publication number
EP0333912A3
EP0333912A3 EP88111565A EP88111565A EP0333912A3 EP 0333912 A3 EP0333912 A3 EP 0333912A3 EP 88111565 A EP88111565 A EP 88111565A EP 88111565 A EP88111565 A EP 88111565A EP 0333912 A3 EP0333912 A3 EP 0333912A3
Authority
EP
European Patent Office
Prior art keywords
evaporation
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP88111565A
Other languages
German (de)
Other versions
EP0333912B1 (en
EP0333912A2 (en
Inventor
Edward Prof. Dr. Schlag
Josef Lindner
Ronald C. Dr. Beavis
J. Dr. Grotemeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Daltonics GmbH and Co KG
Original Assignee
Bruken Franzen Analytik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bruken Franzen Analytik GmbH filed Critical Bruken Franzen Analytik GmbH
Publication of EP0333912A2 publication Critical patent/EP0333912A2/en
Publication of EP0333912A3 publication Critical patent/EP0333912A3/en
Application granted granted Critical
Publication of EP0333912B1 publication Critical patent/EP0333912B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/02—Molecular or atomic beam generation

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
EP88111565A 1988-03-22 1988-07-19 Method for the evaporation of a sample Expired - Lifetime EP0333912B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3809504A DE3809504C1 (en) 1988-03-22 1988-03-22
DE3809504 1988-03-22

Publications (3)

Publication Number Publication Date
EP0333912A2 EP0333912A2 (en) 1989-09-27
EP0333912A3 true EP0333912A3 (en) 1990-03-07
EP0333912B1 EP0333912B1 (en) 1995-06-28

Family

ID=6350311

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88111565A Expired - Lifetime EP0333912B1 (en) 1988-03-22 1988-07-19 Method for the evaporation of a sample

Country Status (3)

Country Link
US (1) US5062935A (en)
EP (1) EP0333912B1 (en)
DE (1) DE3809504C1 (en)

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US6436635B1 (en) 1992-11-06 2002-08-20 Boston University Solid phase sequencing of double-stranded nucleic acids
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US6194144B1 (en) 1993-01-07 2001-02-27 Sequenom, Inc. DNA sequencing by mass spectrometry
US5547835A (en) 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
ATE242485T1 (en) 1993-05-28 2003-06-15 Baylor College Medicine METHOD AND MASS SPECTROMETER FOR THE DESORPTION AND IONIZATION OF ANALYTES
US6020208A (en) * 1994-05-27 2000-02-01 Baylor College Of Medicine Systems for surface-enhanced affinity capture for desorption and detection of analytes
US20020037517A1 (en) 1993-05-28 2002-03-28 Hutchens T. William Methods for sequencing biopolymers
CA2205040C (en) * 1993-11-12 2006-10-17 Joseph A. Jarrell Enhanced resolution maldi tof-ms sample surface
US6071610A (en) * 1993-11-12 2000-06-06 Waters Investments Limited Enhanced resolution matrix-laser desorption and ionization TOF-MS sample surface
US7803529B1 (en) 1995-04-11 2010-09-28 Sequenom, Inc. Solid phase sequencing of biopolymers
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5589685A (en) * 1995-05-26 1996-12-31 Jen Wu; Kuang Matrix enhanced SIMS
US6146854A (en) * 1995-08-31 2000-11-14 Sequenom, Inc. Filtration processes, kits and devices for isolating plasmids
US5777324A (en) 1996-09-19 1998-07-07 Sequenom, Inc. Method and apparatus for maldi analysis
EP1460083B1 (en) 1996-11-06 2006-01-18 Sequenom, Inc. Analysing method and apparatus
AU735416B2 (en) 1996-11-06 2001-07-05 Sequenom, Inc. Dna diagnostics based on mass spectrometry
DE19705762C2 (en) * 1997-02-14 2001-06-07 Rainer Edmund Weinkauf Method and device for generating gas jets
US6207370B1 (en) 1997-09-02 2001-03-27 Sequenom, Inc. Diagnostics based on mass spectrometric detection of translated target polypeptides
US6723564B2 (en) 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
WO2001081829A1 (en) * 2000-04-27 2001-11-01 Brio Technology, Inc. Method and apparatus for processing jobs on an enterprise-wide computer system
US6703366B2 (en) 2001-04-30 2004-03-09 George Jackowski Biopolymer marker indicative of disease state having a molecular weight of 1,896 daltons
US20040224423A1 (en) * 2001-04-30 2004-11-11 George Jackowski Biopolymer marker indicative of disease state having a molecular weight of 2056 daltons
US6620786B2 (en) 2001-04-30 2003-09-16 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having molecular weight of 2937 daltons
US7314717B2 (en) 2001-04-30 2008-01-01 Nanogen Inc. Biopolymer marker indicative of disease state having a molecular weight of 1562 daltons
US7049397B2 (en) * 2001-04-30 2006-05-23 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1211 daltons
US6620787B2 (en) 2001-04-30 2003-09-16 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 2267 daltons
US6627608B2 (en) 2001-04-30 2003-09-30 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1206 daltons
US6693080B2 (en) 2001-04-30 2004-02-17 Syn X Pharma Biopolymer marker indicative of disease state having a molecular weight of 1521 daltons
US6756476B2 (en) 2001-04-30 2004-06-29 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 2021 daltons
US6627607B2 (en) 2001-04-30 2003-09-30 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1845 daltons
US20040198950A1 (en) * 2001-04-30 2004-10-07 George Jackowski Biopolymer marker indicative of disease state having a molecular weight of 1518 daltons
US7087435B2 (en) * 2001-04-30 2006-08-08 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 2753 daltons
US6627606B2 (en) 2001-04-30 2003-09-30 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1465 daltons
US7008800B2 (en) * 2001-04-30 2006-03-07 Artemis Proteomics, Ltd. Biopolymer marker indicative of disease state having a molecular weight of 1077 daltons
US7294688B2 (en) 2001-04-30 2007-11-13 Nanogen Inc. Biopolymer marker indicative of disease state having a molecular weight of 1348 daltons
US6593298B2 (en) 2001-04-30 2003-07-15 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1690 daltons
US6602855B2 (en) 2001-04-30 2003-08-05 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1449 daltons
US20020160533A1 (en) * 2001-04-30 2002-10-31 George Jackowski Biopolymer marker indicative of disease state having a molecular of weight of 1525 daltons
US6677303B2 (en) 2001-04-30 2004-01-13 Syn X Pharma Biopolymer marker indicative of disease state having a molecular weight of 1097 daltons
US6599877B2 (en) 2001-04-30 2003-07-29 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1020 daltons
US7015004B2 (en) * 2001-11-23 2006-03-21 Syn X Pharma, Inc. Inter-alpha trypsin inhibitor biopolymer marker indicative of insulin resistance
US6890763B2 (en) 2001-04-30 2005-05-10 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1350 daltons
US6617308B2 (en) 2001-04-30 2003-09-09 Syn X Pharma, Inc. Biopolymer marker indicative of disease state having a molecular weight of 1865 daltons
US7179610B2 (en) * 2001-11-23 2007-02-20 Nanogen Inc. Complement C3 precursor biopolymer markers indicative of insulin resistance
US7314762B2 (en) 2001-11-21 2008-01-01 Nanogen, Inc. Apolipoprotein biopolymer markers indicative of insulin resistance
US7132244B2 (en) * 2001-11-21 2006-11-07 Syn X Pharma, Inc. Betaine/GABA transport protein biopolymer marker indicative of insulin resistance
US7026129B2 (en) * 2001-11-23 2006-04-11 Syn X Pharma, Inc. IG lambda biopolymer markers predictive of Alzheimers disease
US7097989B2 (en) * 2001-11-23 2006-08-29 Syn X Pharma, Inc. Complement C3 precursor biopolymer markers predictive of type II diabetes
US7125678B2 (en) * 2001-11-23 2006-10-24 Nanogen, Inc. Protein biopolymer markers predictive of type II diabetes
US6890722B2 (en) 2001-11-23 2005-05-10 Syn X Pharma, Inc. HP biopolymer markers predictive of insulin resistance
US7052849B2 (en) * 2001-11-23 2006-05-30 Syn X Pharma, Inc. Protein biopolymer markers predictive of insulin resistance
JP2005510723A (en) * 2001-11-23 2005-04-21 シン．クス ファーマ、インコーポレイテッド Protein biopolymer markers showing age-matched controls
US7179606B2 (en) * 2001-11-23 2007-02-20 Syn X Pharma, Inc. IG heavy chain, IG kappa, IG lambda biopolymer markers predictive of Alzheimer's disease
US7122327B2 (en) * 2001-11-23 2006-10-17 Nanogen Inc. Biopolymer markers indicative of type II diabetes
US7179605B2 (en) 2001-11-23 2007-02-20 Nanogen Inc. Fibronectin precursor biopolymer markers indicative of alzheimer's disease
US20070003974A1 (en) * 2001-11-23 2007-01-04 George Jackowski Cene-E biopolymer marker indicative of age matched control
US7094549B2 (en) * 2001-11-23 2006-08-22 Syn X Pharma, Inc. Fibronectin biopolymer marker indicative of insulin resistance
US7135297B2 (en) * 2001-11-23 2006-11-14 Nanogen Inc. Protein biopolymer markers indicative of insulin resistance
US7074576B2 (en) * 2001-11-23 2006-07-11 Syn X Pharma, Inc. Protein biopolymer markers indicative of alzheimer's disease
US20030113808A1 (en) * 2001-12-13 2003-06-19 George Jackowski Apolipoprotein biopolymer markers predictive of alzheimers disease
JP3530942B2 (en) * 2002-03-05 2004-05-24 独立行政法人通信総合研究所 Molecular beam generation method and apparatus
KR20080073748A (en) 2005-11-16 2008-08-11 노파르티스 아게 Biomarkers for anti-nogo-a antibody treatment in spinal cord injury
FR2995403B1 (en) * 2012-09-13 2014-09-12 Commissariat Energie Atomique METHOD AND DEVICE FOR QUANTITATIVE MEASUREMENT BY LIBS OF BIOMOLECULAR TARGETS ON BIO-CHIP

Citations (1)

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Publication number Priority date Publication date Assignee Title
DE3018455A1 (en) * 1979-05-16 1980-11-27 Varian Mat Gmbh Ionisation of organic samples on conveyor belt - which carries sample from liq. chromatographic appts. into mass spectrometer

Family Cites Families (5)

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US4091256A (en) * 1975-01-16 1978-05-23 The United States Of America As Represented By The Secretary Of The Air Force Pulsed atomic beam apparatus
US4091265A (en) * 1975-08-06 1978-05-23 Racor Industries, Inc. Fuel filter heating assembly
DE2654057B1 (en) * 1976-11-29 1978-04-27 Varian Mat Gmbh Process for the ionization of organic substances, as well as analyzer using this process
DE3224801C2 (en) * 1982-07-02 1986-04-30 Edward William Prof. Dr. 8000 München Schlag Method and device for generating pulsed molecular beams containing large, thermally unstable molecules
US4728796A (en) * 1986-04-10 1988-03-01 Medical College Of Wisconsin Method for ionization of polymers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3018455A1 (en) * 1979-05-16 1980-11-27 Varian Mat Gmbh Ionisation of organic samples on conveyor belt - which carries sample from liq. chromatographic appts. into mass spectrometer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANALYTICAL CHEMISTRY, Band 50, Nr. 7, 19. June 1978, Seiten 985-991, American Chemical Society, Columbus, Ohio, US; M.A. POSTHUMUS et al.: "Laser desorption-mass spectrometry of polar nonvolatile bio-organic molecules" *
ANALYTICAL CHEMISTRY, Band 53, Nr. 1, Januar 1981, Seiten 109-113, American Chemical Society, Columbus, Ohio, US; L.K. LIU et al.: "Matrix-assisted secondary ion mass spectra of biological compounds" *
TRAC (TRENDS IN ANALYTICAL CHEMISTRY), Band 6, Nr. 4, April 1987, Seiten 78-81, Elsevier Science Publishers B.V., Amsterdam, NL; R. ISOBE et al.: "Direct microanalysis by negative ion fast atom bombardment mass spectrometry" *

Also Published As

Publication number Publication date
EP0333912B1 (en) 1995-06-28
US5062935A (en) 1991-11-05
DE3809504C1 (en) 1989-09-21
EP0333912A2 (en) 1989-09-27

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