EP0332660A4 - Bioadhesives - Google Patents

Bioadhesives

Info

Publication number
EP0332660A4
EP0332660A4 EP19880900964 EP88900964A EP0332660A4 EP 0332660 A4 EP0332660 A4 EP 0332660A4 EP 19880900964 EP19880900964 EP 19880900964 EP 88900964 A EP88900964 A EP 88900964A EP 0332660 A4 EP0332660 A4 EP 0332660A4
Authority
EP
European Patent Office
Prior art keywords
bioadhesives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19880900964
Other languages
English (en)
Other versions
EP0332660A1 (en
Inventor
Kathy J. Maugh
David M. Anderson
Robert Strausberg
Susan L. Strausberg
Russ Mccandliss
Tena Wei
David Filpula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enzon Labs Inc
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Publication of EP0332660A1 publication Critical patent/EP0332660A1/en
Publication of EP0332660A4 publication Critical patent/EP0332660A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J189/00—Adhesives based on proteins; Adhesives based on derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP19880900964 1986-11-24 1987-11-24 Bioadhesives Withdrawn EP0332660A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93394586A 1986-11-24 1986-11-24
US933945 1986-11-24
US8245687A 1987-08-07 1987-08-07
US82456 1987-08-07

Publications (2)

Publication Number Publication Date
EP0332660A1 EP0332660A1 (en) 1989-09-20
EP0332660A4 true EP0332660A4 (en) 1990-12-05

Family

ID=26767474

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880900964 Withdrawn EP0332660A4 (en) 1986-11-24 1987-11-24 Bioadhesives

Country Status (5)

Country Link
EP (1) EP0332660A4 (da)
JP (1) JPH02501706A (da)
AU (1) AU1180488A (da)
DK (1) DK414688D0 (da)
WO (1) WO1988003953A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK163987A (da) * 1986-04-25 1987-10-26 Bio Polymers Inc Fremgangsmaade til fremstilling af dopa-holdige bioklaebende proteiner ud fra tyrosin-holdige proteiner
AU1572588A (en) * 1987-03-12 1988-10-10 Genex Corp. Production of bioadhesive precursor protein analogs by genetically-engineered organisms
US5197973A (en) * 1990-12-14 1993-03-30 Creative Biomolecules, Inc. Synthetic bioadhesive
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
AU5659296A (en) * 1995-05-09 1996-11-29 Aizo Matsushiro Pearl protein (nacrein) and process for producing the same
AU5910099A (en) * 1998-09-09 2000-04-03 United States Surgical Corporation Recombinant bioadhesive protein analogs comprising hydroxyproline
EP1589088B1 (en) * 1999-12-17 2007-08-29 BioPolymer Products of Sweden AB New bioadhesive composition comprising a bioadhesive polyphenolic protein, a polymer comprising carbohydrate groups, pharmaceutically acceptable fine filaments and uses thereof
AU2417201A (en) 1999-12-17 2001-06-25 Magnus Qvist New use of a bioadhesive composition comprising a polyphenolic protein
US7618937B2 (en) 2001-07-20 2009-11-17 Northwestern University Peptidomimetic polymers for antifouling surfaces
US8911831B2 (en) 2002-07-19 2014-12-16 Northwestern University Surface independent, surface-modifying, multifunctional coatings and applications thereof
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
DK2405003T3 (da) * 2004-07-28 2015-09-21 Nat Res Council Canada Rekombinante vacciner mod caligid copepoder (havlus) og antigensekvenser deraf
US7622533B2 (en) 2006-08-04 2009-11-24 Nerites Corporation Biomimetic compounds and synthetic methods therefor
WO2012064821A2 (en) 2010-11-09 2012-05-18 Knc Ner Acquisition Sub, Inc. Adhesive compounds and methods use for hernia repair

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496397A (en) * 1984-03-07 1985-01-29 University Of Connecticut Process for purifying and stabilizing catechol-containing proteins and materials obtained thereby
EP0242656A2 (en) * 1986-04-25 1987-10-28 Bio-Polymers, Inc. Method for making dopa-containing bioadhesive proteins from tyroshine-containing proteins
EP0244688A2 (en) * 1986-04-25 1987-11-11 Bio-Polymers, Inc. Adhesives derived from bioadhesive polyphenolic proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687740A (en) * 1984-03-07 1987-08-18 University Of Connecticut Research & Development Corp. Decapeptides produced from bioadhesive polyphenolic proteins
US4585585A (en) * 1984-03-07 1986-04-29 University Of Connecticut Research & Development Corporation Decapeptides produced from bioadhesive polyphenolic proteins
IT1228422B (it) * 1987-07-16 1991-06-17 Montefibre Spa Feltri e tessuti non tessuti a base di fibre poliestere e fibre di vetro e procedimento per ottenerli.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496397A (en) * 1984-03-07 1985-01-29 University Of Connecticut Process for purifying and stabilizing catechol-containing proteins and materials obtained thereby
EP0242656A2 (en) * 1986-04-25 1987-10-28 Bio-Polymers, Inc. Method for making dopa-containing bioadhesive proteins from tyroshine-containing proteins
EP0244688A2 (en) * 1986-04-25 1987-11-11 Bio-Polymers, Inc. Adhesives derived from bioadhesive polyphenolic proteins

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOCHIM. BIOPHYS. ACTA 1986, vol. 872, nos. 1-2, 1986, pages 98-103; K. MARUMO et al.: "Optimization of hydroxylation of tyrosine and tyrosine-containing peptides by mushroom tyrosinase" *
CHEMICAL ABSTRACTS, vol. 105, no. 21, 24th November 1985, abstract no. 186489f, Columbus, Ohio, US; K. MARUMO et al.: "Optimization of hydroxylation of tyrosine and tyrosine-containing peptides by mushroom tyrosinase", & BIOCHIM. BIOPHYS. ACTA 1986, 872(1-2), 98-103 *
GENETIC ENGINEERING NEWS, 14th April 1985; R. JOHNSON: "Genex seeks to clone mussel glue protein" *
SCIENCE, vol. 212, 29th May 1981, pages 1038-1040, AAAS; J.H. WAITE et al.: "Polyphenolic substance of Mytilus edulis: Novel adhesive containing L-dopa and hydroxyproline" *
See also references of WO8803953A1 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 258, no. 5, 10th March 1983, pages 2911-2915, US; J.H. WAITE: "Evidence for repeating 3,4-dihydroxyphenylalanine- and hydroxyproline-containing decapeptide in the adhesive protein of the mussel, mytilus edulis L" *

Also Published As

Publication number Publication date
JPH02501706A (ja) 1990-06-14
WO1988003953A1 (en) 1988-06-02
DK414688A (da) 1988-07-22
DK414688D0 (da) 1988-07-22
EP0332660A1 (en) 1989-09-20
AU1180488A (en) 1988-06-16

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19890524

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 19901018

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Effective date: 19920629

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: ENZON LABS INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19940616