EP0324015A4 - Improved turbidimetric rate inhibition assay for haptens - Google Patents

Improved turbidimetric rate inhibition assay for haptens

Info

Publication number
EP0324015A4
EP0324015A4 EP19880906612 EP88906612A EP0324015A4 EP 0324015 A4 EP0324015 A4 EP 0324015A4 EP 19880906612 EP19880906612 EP 19880906612 EP 88906612 A EP88906612 A EP 88906612A EP 0324015 A4 EP0324015 A4 EP 0324015A4
Authority
EP
European Patent Office
Prior art keywords
haptens
inhibition assay
rate inhibition
improved
improved turbidimetric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19880906612
Other versions
EP0324015A1 (en
Inventor
Frank J. Lucas
Juan Bedevia
Mark L. Shenkin
Brian J. Mcrae
James H. Carter
Harold R. Crews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coulter Electronics Inc
Original Assignee
Coulter Electronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Electronics Inc filed Critical Coulter Electronics Inc
Publication of EP0324015A1 publication Critical patent/EP0324015A1/en
Publication of EP0324015A4 publication Critical patent/EP0324015A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP19880906612 1987-07-21 1988-07-07 Improved turbidimetric rate inhibition assay for haptens Withdrawn EP0324015A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7642587A 1987-07-21 1987-07-21
US76425 1987-07-21

Publications (2)

Publication Number Publication Date
EP0324015A1 EP0324015A1 (en) 1989-07-19
EP0324015A4 true EP0324015A4 (en) 1990-11-07

Family

ID=22131924

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880906612 Withdrawn EP0324015A4 (en) 1987-07-21 1988-07-07 Improved turbidimetric rate inhibition assay for haptens

Country Status (4)

Country Link
EP (1) EP0324015A4 (en)
JP (1) JPH02500133A (en)
AU (1) AU2128388A (en)
WO (1) WO1989000694A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4034509A1 (en) * 1990-10-30 1992-05-07 Boehringer Mannheim Gmbh IMMUNOLOGICAL PRECIPITATION METHOD FOR DETERMINING A BINDABLE ANALYTIC AND REAGENT FOR CARRYING OUT THIS METHOD
DE4124324A1 (en) * 1991-07-23 1993-01-28 Merck Patent Gmbh METHOD AND MEANS FOR TURBIDIMETRIC OR NEPHELOMETRIC DETERMINATION OF ANALYZES
US5371021A (en) * 1992-07-17 1994-12-06 Beckman Instruments, Inc. Initial rate photometric method for immunoassay
EP2005170A1 (en) 2006-03-24 2008-12-24 Aokin Ag Use of additives to lower the rate of a binding reaction
CN102818902A (en) * 2012-08-16 2012-12-12 北京恩济和生物科技有限公司 Detection kit for insulin and preparation method thereof
CN108709993B (en) * 2018-04-02 2021-03-26 深圳上泰生物工程有限公司 Latex-enhanced immunoturbidimetry detection kit and preparation and detection methods thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3301896A1 (en) * 1983-01-21 1984-07-26 Behringwerke Ag, 3550 Marburg Method for the determination of immune complexes
DE3533671A1 (en) * 1984-09-26 1986-03-27 Amano Pharmaceutical Co., Ltd., Nagoya, Aichi METHOD FOR ACCELERATING AN ANTIGO-ANTIBODY REACTION

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
US4401765A (en) * 1981-09-01 1983-08-30 E. I. Du Pont De Nemours And Company Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays
US4460695A (en) * 1981-12-24 1984-07-17 E. I. Dupont De Nemours And Company Method for the removal of interfering substances, including caffeine, in theophylline assays
US4524025A (en) * 1982-06-30 1985-06-18 E. I. Du Pont De Nemours And Company Hybridoma cell lines and monoclonal antibodies to theophylline

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3301896A1 (en) * 1983-01-21 1984-07-26 Behringwerke Ag, 3550 Marburg Method for the determination of immune complexes
DE3533671A1 (en) * 1984-09-26 1986-03-27 Amano Pharmaceutical Co., Ltd., Nagoya, Aichi METHOD FOR ACCELERATING AN ANTIGO-ANTIBODY REACTION

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CLIN. CHEM., vol. 28, no. 4, 1982, pages 659-661; J.W. WU et al.: "Quantitation of haptens by homogeneous immunoprecipitation 1. Automated analysis of gentamicin in serum" *
CLIN. CHIM. ACTA, vol. 76, 1977, pages 377-388, Elsevier/North-Holland Biomedical Press; P.J.J. VAN MUNSTER et al.: "A turbidimetric immnuno assay (TIA) with automated individual blank compensation" *
CLINICA CHIMICA ACTA, vol. 91, 1979, pages 59-65, Elsevier/North-Holland Biomedical Press; T. NISHIKAWA et al.: "Competitive nephelometric immunoassay of theophylline in plasma" *
See also references of WO8900694A1 *

Also Published As

Publication number Publication date
WO1989000694A1 (en) 1989-01-26
JPH02500133A (en) 1990-01-18
EP0324015A1 (en) 1989-07-19
AU2128388A (en) 1989-02-13

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Inventor name: BEDEVIA, JUAN

Inventor name: CARTER, JAMES, H.

Inventor name: SHENKIN, MARK, L.

Inventor name: CREWS, HAROLD, R.

Inventor name: LUCAS, FRANK, J.

Inventor name: MCRAE, BRIAN, J.

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Effective date: 19911206