EP0294380A4 - Stimulation of angiogenesis. - Google Patents

Stimulation of angiogenesis.

Info

Publication number
EP0294380A4
EP0294380A4 EP19870901278 EP87901278A EP0294380A4 EP 0294380 A4 EP0294380 A4 EP 0294380A4 EP 19870901278 EP19870901278 EP 19870901278 EP 87901278 A EP87901278 A EP 87901278A EP 0294380 A4 EP0294380 A4 EP 0294380A4
Authority
EP
European Patent Office
Prior art keywords
angiogenesis
stimulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19870901278
Other languages
German (de)
French (fr)
Other versions
EP0294380A1 (en
Inventor
Brian Richard Mcauslan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scientific Management Pty Ltd filed Critical Biota Scientific Management Pty Ltd
Publication of EP0294380A1 publication Critical patent/EP0294380A1/en
Publication of EP0294380A4 publication Critical patent/EP0294380A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19870901278 1986-02-18 1987-02-10 Stimulation of angiogenesis. Withdrawn EP0294380A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPH466886 1986-02-18
AU4668/86 1986-02-18

Publications (2)

Publication Number Publication Date
EP0294380A1 EP0294380A1 (en) 1988-12-14
EP0294380A4 true EP0294380A4 (en) 1990-02-20

Family

ID=3771473

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19870901278 Withdrawn EP0294380A4 (en) 1986-02-18 1987-02-10 Stimulation of angiogenesis.

Country Status (3)

Country Link
EP (1) EP0294380A4 (en)
JP (1) JPS63502661A (en)
WO (1) WO1987004925A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001166A1 (en) * 1986-08-18 1988-02-25 Biota Scientific Management Pty Ltd Stimulation of angiogenesis and promotion of endothelialisation
US5021404A (en) * 1988-04-20 1991-06-04 The Children's Medical Center Corporation Angiostatic collagen modulators
IL137043A0 (en) * 1998-05-29 2001-06-14 Wisconsin Alumni Res Found Agent and method for modulation of cell migration
CN111743885B (en) * 2020-08-17 2022-03-15 山东省科学院生物研究所 Application of p-hydroxyphenylacetic acid in preventing and/or treating cardiovascular diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7639M (en) * 1967-09-14 1970-02-02
GB1399887A (en) * 1971-06-10 1975-07-02 Prockop D J Composition and methods for controlling collagen synthesis
AU4336972A (en) * 1972-06-13 1973-12-20 Prockop D J Controlling collagen synthesis
CA1281288C (en) * 1984-11-05 1991-03-12 Wilhelm Hoerrmann Tumor therapy
DE3518078A1 (en) * 1985-05-20 1986-11-20 Wilhelm Dr. 8127 Iffeldorf Hoerrmann MEDICINAL PRODUCTS CONTAINING DERIVATIVES OF PROLIN OR HYDROXYPROLIN

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
Am. J. Pathol., Vol. 106, 1982, pages 180-186, American Association of Pathologists, J.A. MADRI et al.: "Aortic endothelial cell migration", whole article, especially page 184. *
Am. J. Pathol., Vol. 112, No. 2, 1983, pages 224-230, American Association of Pathologists, I.Y.R. ADAMSON et al.: "Endothelial injury and repair in radiation-induced pulmonary fibrosis", whole article. *
Cell Biology International Reports, Vol. 9, No. 2, February 1985, pages 175-182, Academic Press Inc., London, GB; B.R. McAUSLAN et al.: "New functions of epidermal growth factor: stimulation of capillary endothelial cell migration and matrix dependent proliferation", whole article. *
Experimental and Molecular Pathology, Vol. 39, 1983, pages 219-229, Academic Press Inc., T.M. HERING et al.: "Type V collagen during granulation tissue development", whole article. *
Experimental Cell Research, Vol. 176, 1988, pages 248-257, Academic Press Inc., B.R. McAUSLAN et al.: "Induction of endothelial cell migration by proline analogs and its relevance to angiogenesis", whole article. *
Prog. Microcir. Res. (Proc. Austr. Symp. Microcirc.), 1st edition, 1981, pages 470-482, Ed. D. GARLICH et al., B.R. McAUSLAN et al.: "A new theory of neovascularisation and its relevance to the clinical use of aspirin", whole article. *
See also references of WO8704925A1 *
The Journal of Investigative Dermatology, Vol. 80, No. 4, 1983, pages 261-267, The Williams & Wilkins Co., E.M.L. TAN et al.: "Proline analogues inhibit human skin fibroblast growth and collagen production in culture", whole article. *
Transplantation, Vol. 36, No. 1, 1983, pages 1-6, The Williams & Wilkins Co., A. NEMLANDER et al.: "Effect of cyclosporine on wound healing", whole article. *

Also Published As

Publication number Publication date
JPS63502661A (en) 1988-10-06
EP0294380A1 (en) 1988-12-14
WO1987004925A1 (en) 1987-08-27

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19880817

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19900220

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19910903

RIN1 Information on inventor provided before grant (corrected)

Inventor name: MCAUSLAN, BRIAN, RICHARD