EP0269127A3 - Nucleotide sequences which are selectively expressed in pre-b cells and probes therefor - Google Patents
Nucleotide sequences which are selectively expressed in pre-b cells and probes therefor Download PDFInfo
- Publication number
- EP0269127A3 EP0269127A3 EP19870117619 EP87117619A EP0269127A3 EP 0269127 A3 EP0269127 A3 EP 0269127A3 EP 19870117619 EP19870117619 EP 19870117619 EP 87117619 A EP87117619 A EP 87117619A EP 0269127 A3 EP0269127 A3 EP 0269127A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- cells
- selectively expressed
- nucleotide sequences
- probe
- polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000523 sample Substances 0.000 title abstract 4
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 210000001948 pro-b lymphocyte Anatomy 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8628433 | 1986-11-27 | ||
GB868628433A GB8628433D0 (en) | 1986-11-27 | 1986-11-27 | Nucleotide sequence |
GB8716497 | 1987-07-14 | ||
GB878716497A GB8716497D0 (en) | 1986-11-27 | 1987-07-14 | Nucleotide sequences |
GB8724100 | 1987-10-14 | ||
GB878724100A GB8724100D0 (en) | 1986-11-27 | 1987-10-14 | Nucleotide sequences |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0269127A2 EP0269127A2 (en) | 1988-06-01 |
EP0269127A3 true EP0269127A3 (en) | 1991-03-13 |
EP0269127B1 EP0269127B1 (en) | 1994-02-23 |
Family
ID=27263220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19870117619 Expired - Lifetime EP0269127B1 (en) | 1986-11-27 | 1987-11-27 | Nucleotide sequences which are selectively expressed in pre-B cells and probes therefor |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0269127B1 (en) |
DE (1) | DE3789138T2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69719726T2 (en) * | 1997-03-27 | 2003-10-16 | Council Of Scientific And Industrial Research, New Delhi | Procedure for the detection of leukemia |
EP1001020A4 (en) * | 1997-07-29 | 2005-03-02 | Sumitomo Electric Industries | Antihuman pre-b cell receptor antibodies |
EP2132312B1 (en) | 2007-03-27 | 2016-01-27 | Sea Lane Biotechnologies,llc. | Constructs and libraries comprising antibody surrogate light chain sequences |
AU2010249046A1 (en) | 2009-05-13 | 2011-12-01 | Sea Lane Biotechnologies, Llc | Neutralizing molecules to influenza viruses |
EP2446032B8 (en) | 2009-06-26 | 2017-03-15 | i2 Pharmaceuticals, Inc. | Expression of surrogate light chains |
US10300140B2 (en) | 2011-07-28 | 2019-05-28 | I2 Pharmaceuticals, Inc. | Sur-binding proteins against ERBB3 |
EP3446707A1 (en) | 2011-12-22 | 2019-02-27 | i2 Pharmaceuticals, Inc. | Surrogate binding proteins |
EP4177267A1 (en) | 2015-02-02 | 2023-05-10 | Children's Health Care d/b/a Children's Minnesota | Anti-surrogate light chain antibodies |
-
1987
- 1987-11-27 EP EP19870117619 patent/EP0269127B1/en not_active Expired - Lifetime
- 1987-11-27 DE DE19873789138 patent/DE3789138T2/en not_active Expired - Fee Related
Non-Patent Citations (4)
Title |
---|
NATURE, vol. 311, 25th October 1984, pages 727-733; G.D. YANCOPOULOS et al.: "Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines" * |
THE EMBO JOURNAL, vol. 5, no. 9, September 1986, pages 2139-2147, IRL Press Ltd, Oxford, GB; N. SAKAGUCHI et al.: "Isolation of a cDNA copy of an RNA species expressed in murine pre-B cells" * |
THE EMBO JOURNAL, vol. 6, no. 1, January 1987, pages 103-107, IRL Press Ltd, Oxford, GB; A. KUDO et al.: "Organization of the murine Ig-related lambda5 gene transcribed selectively in pre-B lymphocytes" * |
THE EMBO JOURNAL, vol. 6, no. 8, August 1987, pages 2267-2272, IRL Press Ltd, Oxford, GB; A. KUDO et al.: "A second gene, VpreB in the lambda5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes" * |
Also Published As
Publication number | Publication date |
---|---|
DE3789138D1 (en) | 1994-03-31 |
EP0269127B1 (en) | 1994-02-23 |
EP0269127A2 (en) | 1988-06-01 |
DE3789138T2 (en) | 1994-05-26 |
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