EP0249736A3 - Ointment for the treatment of skin diseases - Google Patents
Ointment for the treatment of skin diseases Download PDFInfo
- Publication number
- EP0249736A3 EP0249736A3 EP87106773A EP87106773A EP0249736A3 EP 0249736 A3 EP0249736 A3 EP 0249736A3 EP 87106773 A EP87106773 A EP 87106773A EP 87106773 A EP87106773 A EP 87106773A EP 0249736 A3 EP0249736 A3 EP 0249736A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- ointment
- treatment
- skin diseases
- ebselen
- inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3620674 | 1986-06-20 | ||
DE19863620674 DE3620674A1 (en) | 1986-06-20 | 1986-06-20 | Ointment for the treatment of skin diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0249736A2 EP0249736A2 (en) | 1987-12-23 |
EP0249736A3 true EP0249736A3 (en) | 1989-03-29 |
Family
ID=6303316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP87106773A Withdrawn EP0249736A3 (en) | 1986-06-20 | 1987-05-08 | Ointment for the treatment of skin diseases |
Country Status (6)
Country | Link |
---|---|
US (1) | US4784994A (en) |
EP (1) | EP0249736A3 (en) |
JP (1) | JPS635022A (en) |
DE (1) | DE3620674A1 (en) |
DK (1) | DK254887A (en) |
PT (1) | PT84899B (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3720493A1 (en) * | 1987-06-20 | 1989-01-26 | Nattermann A & Cie | MEDICINAL PREPARATIONS WITH MICRONIZED EBSELEN CRYSTALS |
US5288734A (en) * | 1988-10-29 | 1994-02-22 | A. Nattermann & Cie Gmbh | Stable parenteral solution of 2-phenyl-1.2-benzisoselenazol-3(2H)-one and process for producing the same |
US5385726A (en) * | 1990-08-06 | 1995-01-31 | Rhone-Poulenc Rorer Gmbh | Use of 2-phenyl-1,2-benzisoselenazol-3-(2H)-one |
US5817662A (en) * | 1992-11-09 | 1998-10-06 | Cell Therapeutics, Inc. | Substituted amino alkyl compounds |
US5340813A (en) * | 1992-11-09 | 1994-08-23 | Cell Therapeutics, Inc. | Substituted aminoalkyl xanthine compounds |
ES2145065T3 (en) * | 1993-10-27 | 2000-07-01 | Daiichi Seiyaku Co | GRANULAR PREPARATION. |
US6103730A (en) * | 1994-03-24 | 2000-08-15 | Cell Therapeutics, Inc. | Amine substituted compounds |
US5807861A (en) * | 1994-03-24 | 1998-09-15 | Cell Therapeutics, Inc. | Amine substituted xanthinyl compounds |
US5801182A (en) * | 1994-03-24 | 1998-09-01 | Cell Therapeutics, Inc. | Amine substituted compounds |
FR2730930B1 (en) | 1995-02-27 | 1997-04-04 | Oreal | USE OF NO-SYNTHASE INHIBITORS TO REDUCE THE IRRITANT SKIN EFFECT OF PRODUCTS USED IN THE COSMETIC OR PHARMACEUTICAL FIELD |
EP0826371A4 (en) * | 1995-04-27 | 2000-11-15 | Akzo Nobel Nv | External preparation containing emedastine |
FR2740339B1 (en) * | 1995-10-26 | 1997-12-05 | Oreal | USE OF AT LEAST ONE NO-SYNTHASE INHIBITOR IN THE TREATMENT OF SENSITIVE SKIN |
EP1174423A4 (en) | 1999-03-31 | 2008-03-19 | Arne Holmgren | Substrates for thioredoxin reductase |
WO2002053154A1 (en) * | 2000-12-28 | 2002-07-11 | Daiichi Pharmaceutical Co., Ltd. | Pharmaceutical emulsion preparation |
DE10111052A1 (en) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Cosmetic or dermatological preparations for increasing ceramide biosynthesis, e.g. to prevent dryness, containing agents inhibiting the onset of nitrogen monoxide synthase activity |
DE10111050A1 (en) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Use of substances which prevent the NO-synthase of the warm-blooded organism from exerting its effect, for the preparation of cosmetic or dermatological preparations for the treatment and / or prophylaxis of undesired skin pigmentation |
DE10111049A1 (en) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Cosmetic or dermatological preparations for combating inflammatory disorders or dryness of the skin, containing agents inhibiting the onset of nitrogen monoxide synthase activity |
DE10111054A1 (en) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Cosmetic or dermatological preparations for reinforcing skin barrier function, e.g. to prevent dryness, containing agents inhibiting the onset of nitrogen monoxide synthase activity |
US20030086916A1 (en) * | 2001-10-12 | 2003-05-08 | Goligorsky Michael S. | Use of peroxynitrite scavengers or peroxynitrite formation inhibitors that do not diminish nitric oxide synthesis or activity to reverse or prevent premature vascular senescence |
CN1678309A (en) * | 2002-08-26 | 2005-10-05 | S.L.A.制药有限公司 | Tropical formulation comprising at least 5% of metronidazole in white petrolatum and its use in the anal and rectal region |
JP5314931B2 (en) * | 2007-05-25 | 2013-10-16 | 参天製薬株式会社 | Preventive or therapeutic agent for age-related macular degeneration |
IL184620A0 (en) * | 2007-07-15 | 2008-01-20 | Can Fite Biopharma Ltd | Composition for the treatment of inflammation |
US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4263313A (en) * | 1977-02-24 | 1981-04-21 | Kali-Chemie Pharma Gmbh | Topical pharmaceutical formulations, carrier compositions therefor, and preparation thereof |
EP0044971A1 (en) * | 1980-07-17 | 1982-02-03 | A. Nattermann & Cie. GmbH | 2-Phenyl-1.2-benzisoselenazol-3(2H)-one containing pharmaceutical preparations and their use |
GB2128087A (en) * | 1982-10-07 | 1984-04-26 | Ciba Geigy Ag | Topically administrable anti-inflammatory pharmaceutical compositions |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4525347A (en) * | 1978-06-17 | 1985-06-25 | Kowa Company Limited | Antiinflammatory analgesic gelled ointment |
JPS57171912A (en) * | 1981-04-14 | 1982-10-22 | Sumitomo Chem Co Ltd | Cream |
CH643138A5 (en) * | 1983-08-29 | 1984-05-30 | Mepha Ag | INDOMETHACIN CONTAINING, gelatinous OINTMENT. |
US4543251A (en) * | 1983-12-09 | 1985-09-24 | Toko Yakuhin Industry Co., Ltd. | Gel preparations for external application |
US4683242A (en) * | 1985-10-28 | 1987-07-28 | A. H. Robins Company, Incorporated | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters |
-
1986
- 1986-06-20 DE DE19863620674 patent/DE3620674A1/en not_active Ceased
-
1987
- 1987-05-08 EP EP87106773A patent/EP0249736A3/en not_active Withdrawn
- 1987-05-12 US US07/049,727 patent/US4784994A/en not_active Expired - Lifetime
- 1987-05-19 PT PT84899A patent/PT84899B/en unknown
- 1987-05-19 DK DK254887A patent/DK254887A/en not_active Application Discontinuation
- 1987-05-19 JP JP62120325A patent/JPS635022A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4263313A (en) * | 1977-02-24 | 1981-04-21 | Kali-Chemie Pharma Gmbh | Topical pharmaceutical formulations, carrier compositions therefor, and preparation thereof |
EP0044971A1 (en) * | 1980-07-17 | 1982-02-03 | A. Nattermann & Cie. GmbH | 2-Phenyl-1.2-benzisoselenazol-3(2H)-one containing pharmaceutical preparations and their use |
GB2128087A (en) * | 1982-10-07 | 1984-04-26 | Ciba Geigy Ag | Topically administrable anti-inflammatory pharmaceutical compositions |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACTS, Vol. 103, 1985, Columbus, Ohio, USA H. SAFAYHI et al. "A Novel Biologically Active Selenoorganic Compound - V. Inhibition by Ebselen (PZ 51) of Rat Peritoneal Neutrophil Lipoxygenase" page 28, column 2, Abstract No. 98 448v & Biochem. Pharmacol. 1985, 34(15), 2691-2694 * |
E. JUCKER "Fortschritte der Arznei-Mittelforschung", Vol. 28, 1984 Birkhauser Verlag, Basel, Boston, Stuttgart W.J. WECHTER, B.E. LOUGHMAN "Immunology in Drug Research" pages 261-265 * |
Also Published As
Publication number | Publication date |
---|---|
DK254887A (en) | 1987-12-21 |
DK254887D0 (en) | 1987-05-19 |
US4784994A (en) | 1988-11-15 |
DE3620674A1 (en) | 1987-12-23 |
JPS635022A (en) | 1988-01-11 |
EP0249736A2 (en) | 1987-12-23 |
PT84899A (en) | 1987-06-01 |
PT84899B (en) | 1990-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
|
PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
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AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
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17P | Request for examination filed |
Effective date: 19890427 |
|
17Q | First examination report despatched |
Effective date: 19900511 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Withdrawal date: 19910114 |
|
R18W | Application withdrawn (corrected) |
Effective date: 19910114 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: HAGER, JOERG, DR. Inventor name: ROEMER, AXEL, DR. |