EP0199196A3 - Monoclonal antibody and method for the production thereof - Google Patents

Monoclonal antibody and method for the production thereof Download PDF

Info

Publication number
EP0199196A3
EP0199196A3 EP86104913A EP86104913A EP0199196A3 EP 0199196 A3 EP0199196 A3 EP 0199196A3 EP 86104913 A EP86104913 A EP 86104913A EP 86104913 A EP86104913 A EP 86104913A EP 0199196 A3 EP0199196 A3 EP 0199196A3
Authority
EP
European Patent Office
Prior art keywords
production
monoclonal antibody
useful
glycoprotein
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP86104913A
Other languages
German (de)
French (fr)
Other versions
EP0199196A2 (en
Inventor
Sakuji Toyama
Masao Tanihara.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Publication of EP0199196A2 publication Critical patent/EP0199196A2/en
Publication of EP0199196A3 publication Critical patent/EP0199196A3/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A monoclonal antibody specific for an α₁-acid glycoprotein or for at least one antigenic determinant included in a sugar chain of the following formula:
EP86104913A 1985-04-12 1986-04-10 Monoclonal antibody and method for the production thereof Ceased EP0199196A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7896585 1985-04-12
JP78965/85 1985-04-12

Publications (2)

Publication Number Publication Date
EP0199196A2 EP0199196A2 (en) 1986-10-29
EP0199196A3 true EP0199196A3 (en) 1988-04-20

Family

ID=13676608

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86104913A Ceased EP0199196A3 (en) 1985-04-12 1986-04-10 Monoclonal antibody and method for the production thereof

Country Status (3)

Country Link
US (1) US4894442A (en)
EP (1) EP0199196A3 (en)
JP (1) JPS6244199A (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075218A (en) * 1987-12-29 1991-12-24 Biomira, Inc. Screening for antibodies which bind carbohydrate epitopes of tumor-associated antigens, and uses thereof
US4914021A (en) * 1988-03-04 1990-04-03 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
US5241052A (en) * 1988-03-04 1993-08-31 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
US5204450A (en) * 1988-03-04 1993-04-20 New England Deaconess Hospital Corporation Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses
DE3807594A1 (en) * 1988-03-08 1989-09-21 Reutter Werner ANTIBODIES, METHOD FOR THE PRODUCTION THEREOF, OLIGOSACCHARID-HAPTENE AND CLONES FOR THE PRODUCTION OF THE ANTIBODIES AND USE OF THE ANTIBODIES FOR THE DIAGNOSIS AND THERAPY OF TUMORS
JPH0266456A (en) * 1988-08-31 1990-03-06 Saikin Kagaku Kenkyusho:Kk Primary diagnostic method for disease animal and diagnostic reagent used therein and its production
US6333160B1 (en) 1988-08-31 2001-12-25 Keiji Tamura Method and specific diagnostic system for objectively assessing and monitoring the relative homeostasis and health of animals
EP0366820B1 (en) * 1988-11-02 1994-05-04 Kabushiki Kaisha Saikin Kagaku Kenkyujo Method of primary diagnosis for sick animals and diagnostic reagent for such method
KR100499989B1 (en) * 2002-12-27 2005-07-07 네오바이오다임 주식회사 Monoclonal antibody against asialo α1-acid glycoprotein, immunochromatographic strip comprising the monoclonal antibody, and method for diagnosing liver diseases using the immunochromatographic strip
ES2288358B1 (en) * 2005-07-01 2008-11-16 Proyecto De Biomedicina Cima, S.L. FIBROSIS MARKERS.
CA2615846A1 (en) * 2005-07-21 2007-01-25 Genmab A/S Potency assays for antibody drug substance binding to an fc receptor
KR100834932B1 (en) 2006-11-28 2008-06-03 한국생명공학연구원 Kit for diagnosis of hepatic disease using ratio serum asialo-?1-acid glycoprotein concentration and ?1-acid glycoprotein concentration
US8075562B2 (en) * 2007-06-25 2011-12-13 Wisconsin Alumni Research Foundation Controlled release of biopharmaceutical growth factors from hydroxyapatite coating on bioresorbable interference screws used in cruciate ligament reconstruction surgery
JP5358952B2 (en) * 2008-01-10 2013-12-04 和光純薬工業株式会社 Pancreatic cancer marker and method for examining pancreatic cancer
CN101921336B (en) * 2009-06-11 2013-02-27 北京华大蛋白质研发中心有限公司 Monoclonal antibody against human alpha1 acid glycoprotein and preparation method thereof
WO2019189870A1 (en) * 2018-03-30 2019-10-03 積水メディカル株式会社 Antigen treatment method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5735978A (en) * 1980-08-14 1982-02-26 Ishishiba Saabisu Kk MIKAKEHI JUSENBETSUHO

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS/Reviews-Reports-Meetings, vol. 29, 1985, abstract no. 63160; K.F. HILL et al.: "A study of human infarcted myocardial tissue using monoclonal antibodies to acid glycoproteins and creatine kinase-MB", & CLINICAL RESEARCH(US) 1985. VOL 33, NO 2 PART 1 p193A *
BIOLOGICAL ABSTRACTS/Reviews-Reports-Meetings, vol. 29, 1985, abstract no. 6635; K.F. HILL et al.: "A study of human infarcted myocardial tissue using monoclonal antibodies to acid glycoproteins and creatine kinase MB", & CLINICAL RESEARCH(US) 1985. VOL 33, NO 1 p9A *
BIOLOGICAL ABSTRACTS/Reviews-Reports-Meetings, vol. 31, 1986, abstract no. 30236; J.S. IVANCIC et al.: "Monoclonal antibodies for human orosomucoid alpha-1 acid glycoprotein", & FEDERATION PROCEEDINGS(US) 1986. VOL 45, NO 6 p1574 *
CHEMICAL ABSTRACTS, vol. 94, no. 25, 22nd June 1981, page 115, abstract no. 203339f, Columbus, Ohio, US; F. BUCHEGGER et al.: "Use of monoclonal anti-CEA antibodies in immunoadsorbent columns and solid-phase radioimmunoassay", & PROTIDES BIOL. FLUIDS 1980, 28th, 511-15 *
CHEMICAL ABSTRACTS, vol. 97, no. 11, 13th September 1982, page 589, abstract no. 90148j, Columbus, Ohio, US; J. LINDGREN et al.: "Monoclonal antibodies to carcinoembryonic antigen (CEA): characterization and use in a radioimmunoassay for CEA", & ACTA PATHOL., MICROBIOL. IMMUNOL. SCAND., SECT. C 1982,90C(3), 159-62 *
CHEMICAL ABSTRACTS, vol. 98, no. 7, 14th February 1983, page 498, abstract no. 51676f, Columbus, Ohio, US; N. LUKNAR-GABOR et al.: "Characterization of a variant of carcinoembryonic antigen (CEA) using monoclonal and polyclonal anti-CEA antibodies", & BIOCHEM. BIOPHYS. RES. COMMUN. 1982, 109(4), 1270-5 *
PASCAL ABSTR., vol. 84, 1984, abstract no. 260795; Y. OCHI et al.: "Immunochemical identification of an alpha ::(1)-acid glycoprotein-antigenic determinant on carcinoembryonic antigen (CEA) and non-specific cross-reacting antgen (NCA)" *

Also Published As

Publication number Publication date
US4894442A (en) 1990-01-16
EP0199196A2 (en) 1986-10-29
JPS6244199A (en) 1987-02-26

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Inventor name: TOYAMA, SAKUJI

Inventor name: TANIHARA. MASAO