EP0185968B1 - Anal suppository and package therefor - Google Patents

Anal suppository and package therefor Download PDF

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Publication number
EP0185968B1
EP0185968B1 EP85115227A EP85115227A EP0185968B1 EP 0185968 B1 EP0185968 B1 EP 0185968B1 EP 85115227 A EP85115227 A EP 85115227A EP 85115227 A EP85115227 A EP 85115227A EP 0185968 B1 EP0185968 B1 EP 0185968B1
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EP
European Patent Office
Prior art keywords
suppository
packaging
notches
head
anal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP85115227A
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German (de)
French (fr)
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EP0185968A2 (en
EP0185968A3 (en
Inventor
Joachim Klädtke
Ewald Giesselmann
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UCB Pharma GmbH
Original Assignee
Sanol Schwarz GmbH
Schwarz Pharma AG
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Publication date
Application filed by Sanol Schwarz GmbH, Schwarz Pharma AG filed Critical Sanol Schwarz GmbH
Priority to AT85115227T priority Critical patent/ATE50142T1/en
Publication of EP0185968A2 publication Critical patent/EP0185968A2/en
Publication of EP0185968A3 publication Critical patent/EP0185968A3/en
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Publication of EP0185968B1 publication Critical patent/EP0185968B1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/08—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/321—Both sheets being recessed
    • B65D75/323—Both sheets being recessed and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments

Definitions

  • the present invention relates to an introduction to the rectum, i.e. suppository to be administered rectally, a so-called anal suppository, with improved properties with regard to its introduction into the rectum and packaging therefor such that the suppository can be inserted without the aid of the fingers.
  • the form of administration of the suppository is rectally administered in the suppository base mass distributed active ingredients a marverbre i tetes means, be it for the local treatment of the rectum, either because oral or parenteral administration of the active substance is not possible is not desired or.
  • the suppository base used is, among other things, cocoa butter, vegetable or animal fats, hydrogenated oils, mixtures of fats, wax and walrus, resin-free ozokerite, hard paraffin, glycerin gelatin and glycerine soap gels or polyethylene oxides, all suppository bases that are solid at room temperature and soften or liquefy at body temperature and thus release the active substances contained in them for absorption by the mucous membranes of the rectum (cf. Hagers Handbuch der Pharmaceuticaltechnik, Volume Vlla, 4th edition, Springer-Verlag, 1971, p. 664; F. Gstirner, Introduction to Process Engineering in Pharmaceutical Forming, 5th ed. (1973),ticianl.
  • suppositories today have a generally torpedo-like shape, the head being tapered to facilitate rectal insertion, and the suppository at the head being somewhat thicker than at the end of the suppository, ie tapering slightly towards the end.
  • suppositories for rectal use generally have a weight of approx. 2 g for adults and approx. 1 g for children. Suppositories up to 2.5 g are often on the market.
  • the suppository according to the invention with packaging is characterized in that the suppository is provided with notches in the conical end of the suppository from the running part near the end, and that the packaging has indentations which engage in the notches in the suppository.
  • the suppository does not need to be removed from the packaging for insertion, but the packaging is unfolded, the suppository still being held in the packaging by the indentations and corresponding indentations when the packaging is opened, and the suppository at the height while touching the packaging of the tapered end can be inserted into the anus.
  • the suppository can be reduced by a total of approx. 10% by reducing the previous suppository base by up to 20%, thus lengthening the parts of the packaging strip that are not connected to one another and serve to grip the opening of the packaging, thereby lengthening the suppository Grip resistance for consumers can be increased using the same packaging materials and machines.
  • touching the suppository with the finger is not necessary, because the sphincter of the anus grips the suppository securely without the risk of closing the anus serving Sphincter pushes the suppository back out. Avoiding the need for finger pounding contributes to the hygiene of such suppositories.
  • the previous suppository casting machines can also continue to be used, with only the molding tools of the molding and casting machines that are normally used being changed.
  • the possibility of a wider configuration of the parts of the packaging strip which serve to grip when opening the packaging enables a further measure to simplify the opening of the packaging for the consumer.
  • the design of the suppository according to the invention allows a shortening by approximately 10% of the previously required suppository length, so that the handle tabs can be widened in the associated packaging.
  • With a colored print the consumer will quickly recognize this relief, even if he has poor eyesight due to age or other reasons, and will easily separate the two tabs, which are located one above the other.
  • FIG. 1 shows suppositories together with their packaging, which is customary today, in the form of a strip 1, in which the suppositories 2 lie next to one another in the departments provided for this purpose. While the surroundings 3 are suitably sealed around the suppository compartments, the front ends 4 of the strips lie loosely on top of one another in the form of tabs.
  • a packaging compartment is torn off along the perforation 6, starting at the notch 5, and the two packaging foils welded to one another can be separated using the loosely arranged tabs 4 and the packaging of the individual suppository opened.
  • the packaging flaps in the packaging for the usual torpedo-shaped suppositories are relatively narrow due to the shape and length of the torpedo-shaped suppositories and do not give sufficient grip when the packaging is torn open.
  • the suppository according to the invention with the spherical or onion-shaped head is shorter with the smaller suppository mass, so that the tabs 4 which remain after the suppository compartments have been sealed are longer.
  • the length is such that the tabs can be of different lengths, so that one tab is surmounted by the other tab with its part 4a, which is conspicuous, e.g. B.
  • notches are provided on the conical tapered shaft 8 near the rear end and corresponding indentations 7 are provided in the packaging, so that the taper can be held with the rear part after tearing open the individual packaging for the individual suppository and bending apart the front parts , without the risk of the suppository falling out, and thus the suppository can be inserted into the anus in a hygienic manner without touching it.

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  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • External Artificial Organs (AREA)

Abstract

1. Anal suppository and package therefor, which suppository (2) contains the active agent in usual amounts and consists of usual basic material, has a head part of increased diameter and has a laced part behind its head part, whereafter the suppository (2) in usual manner tapers off conically towards the end of the suppository, characterized in that the suppository (2) in its conically tapering end part and close to its end has notches and the packaging (1) also shows notches (7) engaging into the notches of the suppository (2).

Description

Die vorliegende Erfindung betrifft ein zur Einführung in den Mastdarm, d.h. rektal zu verabreichendes Zäpfchen, ein sogenanntes Analzäpfchen, mit in bezug auf seine Einführung in den Mastdarm verbesserten Eigenschaften und Verpackung hierfür derart, daß das Zäpfchen eingeführt werden kann ohne Zuhilfenahme der Finger.The present invention relates to an introduction to the rectum, i.e. suppository to be administered rectally, a so-called anal suppository, with improved properties with regard to its introduction into the rectum and packaging therefor such that the suppository can be inserted without the aid of the fingers.

Die Verabreichungsform des Zäpfchens ist ein weitverbreitetes Mittel, in der Zäpfchengrundmasse verteilte Wirkstoffe rektal zu verabreichen, sei es zur lokalen Behandlung im Mastdarm, sei es, weil eine orale oder parenterale Verabreichung des Wirkstoffs nicht möglich oder nicht gewünscht ist. Als Zäpfchengrundmasse werden dabei u.a. Kakaobutter, pflanzliche oder tierische Fette, hydrierte Öle, Mischungen aus Fetten, Wachs und Walrat, harzfreies Ozokerit, Hartparaffin, Glycerin-Gelatine und Glycerin-Seifen-Gele oder Polyethylenoxide verwendet, alles Zäpfchengrundmassen, die bei Zimmertemperatur fest sind und bei Körpertemperatur erweichen oder sich verflüssigen und so die in ihnen enthaltenen Wirkstoffe zur Absorption durch die Schleimhäute des Mastdarms freigeben (vgl. Hagers Handbuch der pharmazeutischen Praxis, Band Vlla, 4. Aufl., Springer-Verlag, 1971, S. 664; F. Gstirner, Einführung in die Verfahrenstechnik der Arzneiformung, 5. Aufl. (1973), Wissenschaftl. Verlagsgesellschaft mbH, Stuttgart, S. 149 - 151; Der Apotheker-Praktikant, 8. Aufl. (1967), Wissenschaftl. Verlagsgesellschaft mbH, Stuttgart, S. 189 - 191). Diese Zäpfchen haben heute im allgemeinen torpedoähnliche Form, wobei der Kopf konisch zugespitzt ist, um die rektale Einführung zu erleichtern, und das Zäpfchen am Kopf etwas dicker als am Zäpfchenende ist, d.h. zum Ende hin schwach konisch zuläuft. Gemäß DABB-BRD haben Suppositorien zur rektalen Anwendung im allgemeinen ein Gewicht von ca. 2 g für Erwachsene und von ca. 1 g für Kinder. Im Handel sind häufig Zäpfchen bis 2,5 g.The form of administration of the suppository is rectally administered in the suppository base mass distributed active ingredients a weitverbre i tetes means, be it for the local treatment of the rectum, either because oral or parenteral administration of the active substance is not possible is not desired or. The suppository base used is, among other things, cocoa butter, vegetable or animal fats, hydrogenated oils, mixtures of fats, wax and walrus, resin-free ozokerite, hard paraffin, glycerin gelatin and glycerine soap gels or polyethylene oxides, all suppository bases that are solid at room temperature and soften or liquefy at body temperature and thus release the active substances contained in them for absorption by the mucous membranes of the rectum (cf. Hagers Handbuch der Pharmaceutical Praxis, Volume Vlla, 4th edition, Springer-Verlag, 1971, p. 664; F. Gstirner, Introduction to Process Engineering in Pharmaceutical Forming, 5th ed. (1973), Wissenschaftl. Verlagsgesellschaft mbH, Stuttgart, pp. 149 - 151; Der Apotheker-Praktikant, 8th ed. (1967), Wissenschaftl. Verlagsgesellschaft mbH, Stuttgart, Pp. 189-191). These suppositories today have a generally torpedo-like shape, the head being tapered to facilitate rectal insertion, and the suppository at the head being somewhat thicker than at the end of the suppository, ie tapering slightly towards the end. According to DABB-BRD, suppositories for rectal use generally have a weight of approx. 2 g for adults and approx. 1 g for children. Suppositories up to 2.5 g are often on the market.

Diese bisherigen Analzäpfchen haben den Nachteil, daß sie, wenn sie nicht genügend weit rektal eingeführt und sogar mit dem Finger - in unhygienischer Weise - nachgestoßen werden, aufgrund der Gleitfähigkeit der üblichen Zäpfchengrundmasse und dem Bestreben des Anusschließmuskels den Anus geschlossen zu halten, häufig wieder ausgestoßen werden. Um dies zu verhindern, sind auch Zäpfchen bekannt, die einen verdickten Kopf haben und hinter dem Kopf eine Einschnürung aufweisen (s. z. B. GB-A-252 363). Ein Analtäpfchen und eine Verpackung hierfür, weiche die Anwendung des Zäpfchens ohne Verschmutzung der Hände ermöglicht, geht aus der DE-A-3 220 249 als bekannt hervor.These previous anal suppositories have the disadvantage that, if they are not inserted far enough rectally and even pushed in with the finger - in an unsanitary manner - due to the slidability of the usual suppository base and the endeavor of the anus sphincter to keep the anus closed, they are often expelled again will. To prevent this, suppositories are also known which have a thickened head and a constriction behind the head (see e.g. GB-A-252 363). An anal pill and a packaging for it, which enables the use of the suppository without soiling the hands, is known from DE-A-3 220 249.

Bei den bisherigen torpedoförmigen Zäpfchen z. B. mit einem Gewicht von ca. 2,4 g mit den Ma-Ben von 30,5 mm Länge, 9,6 mm im Durchmesser am Ende des Zäpfchens und 11,7 mm an der breitesten Stelle des Kopfes bestehen bezüglich der Aufreißbarkeit der Zäpfchenverpackung Probleme. Die Zäpfchen werden heute im allgemeinen auf Automaten in streifenförmigen Verpackungen verpackt, wobei sechs Zäpfchen nebeneinander und getrennt voneinander versiegelt zu liegen kommen und die einzelnen Zäpfchenverpackungen durch Perforationen zwischen den Zäpfchen abgetrennt werden können. Die Verpackungen werden z. B. aus Kunststofffolien in Tiefziehautomaten geformt, jeweils aus zwei übereinanderliegenden, teilweise verschweißten Folien so, daß der Form des Zäpfchens entsprechende, am unteren Ende offene Näpfe entstehen, die so gebildeten Näpfe mit der Zäpfchenmasse gefüllt und schließlich am unteren Ende ebenfalls versiegelt werden. Am Kopfende sind dabei nichtversiegelte Laschen belassen. Der Benutzer trennt ein Zäpfchen aus dem Verband mittels angebrachter Perforationen ab, öffnet die Verpackung durch Auseinanderfalten der am Kopf befindlichen Laschen und entnimmt das Zäpfchen, das bei Auseinanderreißen der Form im allgemeinen aus der Verpackung herausfällt und - wie aus hygienischen Gründen unerwünscht - mit der Hand verabreicht wird.In the previous torpedo-shaped suppositories such. B. with a weight of about 2.4 g with the Ma-Ben of 30.5 mm in length, 9.6 mm in diameter at the end of the suppository and 11.7 mm at the widest point of the head exist with regard to the tearability of the Suppository packaging problems. The suppositories are now generally packaged on machines in strip-shaped packagings, with six suppositories lying side by side and separated from one another and the individual suppository packs being able to be separated by perforations between the suppositories. The packaging is e.g. B. molded from plastic films in thermoforming machines, each of two superimposed, partially welded foils so that the shape of the suppository corresponding, at the lower end open cups are formed, the cups thus formed are filled with the suppository mass and finally also sealed at the lower end. Unsealed tabs are left at the head end. The user removes a suppository from the bandage by means of perforations, opens the packaging by unfolding the tabs on the head and removes the suppository, which generally falls out of the packaging when the shape is torn apart and - as is undesirable for hygienic reasons - by hand is administered.

Es ist Aufgabe der vorliegenden Erfindung, ein Analzäpfchen mit verdicktem Kopf und zugehöriger Verpackung zu schaffen, mit der das Zäpfchen, ohne Zuhilfenahme der Finger und ohne es zu berühren, leichter und sicherer in den Anus eingeführt werden kann, d.h. die es erlaubt, das Zäpfchen trotz der gleitfähigen Zäpfchenmasse sicher zu verabreichen, ohne daß das Zäpfchen dabei angefaßt werden muß.It is an object of the present invention to provide an anal suppository with a thickened head and associated packaging, with which the suppository can be inserted more easily and safely into the anus without the aid of the fingers and without touching it, i.e. which allows the suppository to be safely administered despite the slippery suppository mass, without having to touch the suppository.

Das erfindungsgemäße Zäpfchen mit Verpakkung ist dadurch gekennzeichnet, daß das Zäpfchen im konisch zum Zäpfchenende aus laufenden Teil nahe dem Ende mit Einkerbungen versehen ist, und daß die Verpackung Einbuchtungen aufweist, die in die Einkerbungen des Zäpfchens eingreifen. Hierdurch braucht das Zäpfchen zum Einführen nicht aus der Verpackung herausgenommen zu werden, sondern die Verpackung wird auseinandergefaltet, wobei das Zäpfchen beim Öffnen der Verpackung durch die Einkerbungen und entsprechenden Einbuchtungen noch in der Verpackung gehalten wird, und das Zäpfchen unter Anfassen der Verpackung auf der Höhe des konisch zulaufenden Endes in den Anus eingeführt werden kann.The suppository according to the invention with packaging is characterized in that the suppository is provided with notches in the conical end of the suppository from the running part near the end, and that the packaging has indentations which engage in the notches in the suppository. As a result, the suppository does not need to be removed from the packaging for insertion, but the packaging is unfolded, the suppository still being held in the packaging by the indentations and corresponding indentations when the packaging is opened, and the suppository at the height while touching the packaging of the tapered end can be inserted into the anus.

Durch die erfindungsgemäße Zäpfchenform kann unter Verminderung der bisherigen Zäpfchengrundmasse um bis zu 20 % das Zäpfchen insgesamt um ca. 10 % verkürzt werden und so die am Kopfende befindlichen, nicht miteinander verbundenen, dem Anfassen beim Öffnen der Verpackung dienenden Teile des Verpackungsstreifens verlängert und dadurch die Greiffestigkeit für den Verbraucher erhöht werden unter Verwendung der gleichen Verpackungsmaterialien und -maschinen. Überraschenderweise ist zum sicheren Einführen des Zäpfchens in den Anus trotz der Verkürzung um ca. 10 % eine Berührung des Zäpfchens mit dem Finger nicht notwendig, denn der Schließmuskel des Anus greift das Zäpfchen sicher, ohne daß es Gefahr läuft, daß der dem Verschließen des Anus dienende Schließmuskel das Zäpfchen wieder nach außen drängt. Die Vermeidung der Notwendigkeit eines Nachstoßens mit dem Finger trägt zur Hygiene der Anwendung derartiger Zäpfchen bei. Auch können die bisherigen Zäpfchengießmaschinen weiter verwendet werden, wobei nur die Formwerkzeuge der üblicherweise verwendeten Form-und Gießautomaten zu verändern sind.With the suppository shape according to the invention, the suppository can be reduced by a total of approx. 10% by reducing the previous suppository base by up to 20%, thus lengthening the parts of the packaging strip that are not connected to one another and serve to grip the opening of the packaging, thereby lengthening the suppository Grip resistance for consumers can be increased using the same packaging materials and machines. Surprisingly, in order to safely insert the suppository into the anus, despite the shortening by approx. 10%, touching the suppository with the finger is not necessary, because the sphincter of the anus grips the suppository securely without the risk of closing the anus serving Sphincter pushes the suppository back out. Avoiding the need for finger pounding contributes to the hygiene of such suppositories. The previous suppository casting machines can also continue to be used, with only the molding tools of the molding and casting machines that are normally used being changed.

Die Möglichkeit der breiteren Gestaltung der dem Anfassen beim Öffnen der Verpackung dienenden Teile des Verpackungsstreifens ermöglicht eine weitere Maßnahme zur Vereinfachung des Öffnens der Verpackung für den Verbraucher. Bei der bisherigen Zäpfchenlänge und der damit notwendigen schmalen Ausgestaftung der Anfaßlaschen mußten diese gleichlang ausgeführt werden. Der Verbraucher übersahhäufig die Anfaßlaschen und hatte entsprechende Schwierigkeiten bei der Anwendung des Zäpfchens. Die Gestaltung des erfindungsgemäßen Zäpfchens erlaubt eine Verkürzung um ca. 10 % der bisher notwendigen Zäpfchenlänge, so daß bei der zugehörigen Verpackung die Anfaßlaschen verbreitert werden können. Durch einen farbigen Aufdruck wird der Verbraucher, auch wenn er infolge Alters- oder aus anderen Gründen verschlechtertes Augenlicht hat, schnell diese Erleichterung erkennen und die beiden eng übereinanderliegenden Laschen leicht trennen.The possibility of a wider configuration of the parts of the packaging strip which serve to grip when opening the packaging enables a further measure to simplify the opening of the packaging for the consumer. With the previous length of suppository and the necessary narrow lacing of the grip tabs, these had to be of the same length. The consumer frequently overlooked the handle tabs and had corresponding difficulties in using the suppository. The design of the suppository according to the invention allows a shortening by approximately 10% of the previously required suppository length, so that the handle tabs can be widened in the associated packaging. With a colored print, the consumer will quickly recognize this relief, even if he has poor eyesight due to age or other reasons, and will easily separate the two tabs, which are located one above the other.

Die beiliegende Zeichnung dient der weiteren Erläuterung der vorliegenden Erfindung.

  • Fig. 1 zeigt die Ausführungsform der erfindungsgemäßen Zäpfchen und der Verpackung dazu. Der kugelförmige Kopf läuft zur Spitze des Zäpfchens hin schwach konisch aus, d.h. der Kopf des Zäpfchens ist zwiebelförmig ausgebildet.
The accompanying drawing serves to further explain the present invention.
  • Fig. 1 shows the embodiment of the suppository according to the invention and the packaging therefor. The spherical head tapers slightly conically towards the tip of the suppository, ie the head of the suppository is formed onion-shaped.

Die Fig. 1 zeigt Zäpfchen zusammen mit ihrer heute üblichen, in Form eines Streifens 1 ausgebildeten Verpackung, bei dem die Zäpfchen 2 nebeneinander in den hierfür vorgesehenen Abteilungen liegen. Während die Umgebung 3 um die Zäpfchenabteilungen herum in geeigneter Weise versiegelt sind, liegen die vorderen Enden 4 der Streifen in Form von Laschen lose aufeinander. Beim Gebrauch eines Zäpfchens wird ein Verpackungsabteil entlang der Perforation 6, beginnend an der Kerbe 5, abgerissen und können die beiden aufeinandergeschweißten Verpackungsfolien mit Hilfe der lose aufeinanderliegenden Laschen 4 auseinandergetrennt und so die Verpackung des einzelnen Zäpfchens geöffnet werden. Die Verpackungslaschen bei der Verpackung für die üblichen torpedoförmigen Zäpfchen sind aufgrund der Form und Länge des torpedoförmigen Zäpfchens relativ schmal und geben nicht genügend Griff beim Aufreißen der Verpackung. Das erfindungsgemäße Zäpfchen mit dem kugel- oder zwiebelförmigen Kopf ist jedoch bei der geringeren Zäpfchenmasse kürzer, so daß die Laschen 4, die nach Versiegelung der Zäpfchenabteile verbleiben, länger sind. Die Länge ist dabei so, daß die Laschen unterschiedlich lang ausgeführt werden können, so daß die eine Lasche von der anderen Lasche mit ihrem Teil 4a überragt wird, die augenfällig, z. B. durch geeignete Färbung, gestaltet werden kann, so daß auch Personen mit verschlechtertem Augenlicht erleichtert die Laschen voneinandertrennen und so die versiegelten Zäpfchenabteile leichter öffnen können. In der erfindungsgemäßen Ausführungsform sind am konisch zulaufenden Zäpfchenschaft 8 nahe dem hinteren Ende Einkerbungen und sind in der Verpackung entsprechende Einbuchtungen 7 vorgesehen, so daß das Zäpfchen nach Aufreißen der einzelnen Verpackung für das einzelne Zäpfchen und Auseinanderbiegen der vorderen Teile mit dem hinteren Teil gehalten werden kann, ohne Gefahr des Herausfallens des Zäpfchens, und so das Zäpfchen, ohne es selbst anzufassen, auf hygienische Weise in den Anus eingeführt werden kann.1 shows suppositories together with their packaging, which is customary today, in the form of a strip 1, in which the suppositories 2 lie next to one another in the departments provided for this purpose. While the surroundings 3 are suitably sealed around the suppository compartments, the front ends 4 of the strips lie loosely on top of one another in the form of tabs. When using a suppository, a packaging compartment is torn off along the perforation 6, starting at the notch 5, and the two packaging foils welded to one another can be separated using the loosely arranged tabs 4 and the packaging of the individual suppository opened. The packaging flaps in the packaging for the usual torpedo-shaped suppositories are relatively narrow due to the shape and length of the torpedo-shaped suppositories and do not give sufficient grip when the packaging is torn open. However, the suppository according to the invention with the spherical or onion-shaped head is shorter with the smaller suppository mass, so that the tabs 4 which remain after the suppository compartments have been sealed are longer. The length is such that the tabs can be of different lengths, so that one tab is surmounted by the other tab with its part 4a, which is conspicuous, e.g. B. by suitable coloring, can be designed so that people with poor eyesight easier to separate the tabs from each other and so can open the sealed suppository compartments more easily. In the embodiment according to the invention, notches are provided on the conical tapered shaft 8 near the rear end and corresponding indentations 7 are provided in the packaging, so that the taper can be held with the rear part after tearing open the individual packaging for the individual suppository and bending apart the front parts , without the risk of the suppository falling out, and thus the suppository can be inserted into the anus in a hygienic manner without touching it.

Claims (3)

1. Anal suppository and package therefor, which suppository (2) contains the active agent in usual amounts and consists of usual basic material, has a head part of increased diameter and has a laced part behind its head part, whereafter the suppository (2) in usual manner tapers off conically towards the end of the suppository, characterized in that the suppository (2) in its conically tapering end part and close to its end has notches and the packaging (1) also shows notches (7) engaging into the notches of the suppository (2).
2. Anal suppository and package therefor acoor- ding to claim 1, characterized in that the head of the suppository (2) is formed ball-shaped and is slightly tapering off towards the tip of the suppository.
3. Anal suppository and package therefor according to claim 1 or 2, characterized in that the head strips (4) of the package are made with different lengths.
EP85115227A 1984-12-13 1985-11-30 Anal suppository and package therefor Expired - Lifetime EP0185968B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT85115227T ATE50142T1 (en) 1984-12-13 1985-11-30 ANAL SUPPLEMENTS AND PACKAGING THEREOF.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3445394 1984-12-13
DE19843445394 DE3445394A1 (en) 1984-12-13 1984-12-13 ANALZAFEFCHEN AND PACKING HERE

Publications (3)

Publication Number Publication Date
EP0185968A2 EP0185968A2 (en) 1986-07-02
EP0185968A3 EP0185968A3 (en) 1986-12-17
EP0185968B1 true EP0185968B1 (en) 1990-02-07

Family

ID=6252621

Family Applications (1)

Application Number Title Priority Date Filing Date
EP85115227A Expired - Lifetime EP0185968B1 (en) 1984-12-13 1985-11-30 Anal suppository and package therefor

Country Status (3)

Country Link
EP (1) EP0185968B1 (en)
AT (1) ATE50142T1 (en)
DE (2) DE3445394A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10246003B4 (en) * 2002-10-02 2005-06-30 Anliker, Markus, Dr.med. Suppository

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10813963B2 (en) 2018-09-04 2020-10-27 Babak Ghalili Veterinary cannabinoid and menthol compositions and methods
US10751299B2 (en) * 2018-09-04 2020-08-25 Babak Ghalili Cannabinoid and menthol compositions and methods
WO2021177938A1 (en) * 2020-03-02 2021-09-10 Babak Ghalili Veterinary cannabinoid and menthol compositions and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126887A (en) * 1964-03-31 gordon
GB252363A (en) * 1925-05-22 1927-01-27 Belge Des Produits Rationnels Improvements in suppositories and means for the insertion of the same
US3039246A (en) * 1959-08-06 1962-06-19 Ivers Lee Co Suppository package and method of making it
DE3220249A1 (en) * 1981-10-26 1983-05-05 Tadashi Ikeda Osaka Yagi Introduction aid for suppositories

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10246003B4 (en) * 2002-10-02 2005-06-30 Anliker, Markus, Dr.med. Suppository

Also Published As

Publication number Publication date
DE3445394A1 (en) 1986-06-19
ATE50142T1 (en) 1990-02-15
EP0185968A2 (en) 1986-07-02
EP0185968A3 (en) 1986-12-17
DE3575858D1 (en) 1990-03-15

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