EP0127605A3 - Process for obtaining preparations of human blood plasma - Google Patents
Process for obtaining preparations of human blood plasma Download PDFInfo
- Publication number
- EP0127605A3 EP0127605A3 EP84890089A EP84890089A EP0127605A3 EP 0127605 A3 EP0127605 A3 EP 0127605A3 EP 84890089 A EP84890089 A EP 84890089A EP 84890089 A EP84890089 A EP 84890089A EP 0127605 A3 EP0127605 A3 EP 0127605A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- plasma
- preparations
- human blood
- blood plasma
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Es wird ein verfahren zur Herstellung von Präparationen aus menschlichem Blutplasma, wie Gerinnungsfaktor präparationen, Globulinpräparationen, Plasmaenzymen und Plasmaenzyminhibitoren beschrieben, wobei der Plasmafrak tion zur Inaktivierung etwa vorhandener vermehrungsfähiger Krankheitserreger Verbindungsgemische zugesetzt werden, die in freie Radikale zerfallen. Solche Verbindungen können Alkylperoxide, Acylperoxide, Peroxysäuren, Peroxyester und Peroxycarbonate sein. Es können Katalysatoren mitverwen det werden. There is a process for the preparation of preparations from human blood plasma, such as coagulation factor preparations, globulin preparations, plasma enzymes and Plasma enzyme inhibitors described, the plasma fracture tion to inactivate any existing reproductive Pathogen compound mixtures are added that decay into free radicals. Such connections can Alkyl peroxides, acyl peroxides, peroxy acids, peroxy esters and Be peroxycarbonates. Catalysts can be used be det.
In Versuchen, bei welchen Hundehepatitisvirus zu den Plasmafraktionen zugesetzt wird, wird gezeigt, daß nach Behandlung der Plasmafraktionen mit freien Radikalen der Virustiter um mindestens vier Zehnerpotenzen abfällt, während die Aktivität der Plasmafraktionen im wesentlichen erhalten bleibt. In experiments in which canine hepatitis virus If plasma fractions are added, it is shown that after Treatment of plasma fractions with free radicals Virus titer drops by at least four powers of ten, while the activity of the plasma fractions essentially preserved.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT1983/83 | 1983-05-31 | ||
AT0198383A AT382078B (en) | 1983-05-31 | 1983-05-31 | METHOD FOR PRODUCING PREPARATIONS FROM HUMAN BLOOD PLASMA |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0127605A2 EP0127605A2 (en) | 1984-12-05 |
EP0127605A3 true EP0127605A3 (en) | 1987-01-28 |
Family
ID=3525303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP84890089A Withdrawn EP0127605A3 (en) | 1983-05-31 | 1984-05-17 | Process for obtaining preparations of human blood plasma |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0127605A3 (en) |
JP (1) | JPS606620A (en) |
AT (1) | AT382078B (en) |
CA (1) | CA1211709A (en) |
DK (1) | DK265084A (en) |
ES (1) | ES532863A0 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3805459A1 (en) * | 1988-02-22 | 1989-08-31 | Biotest Pharma Gmbh | METHOD FOR STERILIZING BLOOD, PLASMA, BLOOD AND PLASMA DERIVATIVES, CELL SUSPENSIONS OR THE LIKE |
GB9015910D0 (en) * | 1990-07-19 | 1990-09-05 | Univ Bruxelles | Novel use |
EP0605690A4 (en) * | 1992-06-29 | 1994-12-07 | Edward Shanbrom | Povidone hydrogen peroxide preservation of blood, tissues and biological fluids. |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1617500A1 (en) * | 1967-03-30 | 1971-04-08 | Gaebelein Klaus Dipl Chem Dr | Preservation of blood plasma |
FR2400906A1 (en) * | 1978-08-22 | 1979-03-23 | Evers Hans | Disinfecting and cleaning contact lenses without allergic reaction - with cold soln. contg. ene:diol redox system, water-soluble oxidising agent and opt. heavy metal salt catalyst |
EP0037078A2 (en) * | 1980-03-27 | 1981-10-07 | Green Cross Corporation | Process for heat treatment of aqueous solution containing human blood coagulation factor XIII |
WO1982003871A1 (en) * | 1981-04-27 | 1982-11-11 | Baxter Travenol Lab | Process for making novel blood clotting enzyme compositions |
DE3134050A1 (en) * | 1981-08-28 | 1983-03-10 | Dr. Franz Köhler Chemie GmbH, 6146 Alsbach | Solution for sterilising and removing pyrogens from stainless steel lines and filters in a closed system |
EP0139994A1 (en) * | 1983-08-25 | 1985-05-08 | Allergan, Inc. | Process and kit for disinfection of contact lenses |
-
1983
- 1983-05-31 AT AT0198383A patent/AT382078B/en not_active IP Right Cessation
-
1984
- 1984-05-17 EP EP84890089A patent/EP0127605A3/en not_active Withdrawn
- 1984-05-18 CA CA000454640A patent/CA1211709A/en not_active Expired
- 1984-05-25 ES ES532863A patent/ES532863A0/en active Granted
- 1984-05-29 DK DK265084A patent/DK265084A/en not_active Application Discontinuation
- 1984-05-30 JP JP59112193A patent/JPS606620A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1617500A1 (en) * | 1967-03-30 | 1971-04-08 | Gaebelein Klaus Dipl Chem Dr | Preservation of blood plasma |
FR2400906A1 (en) * | 1978-08-22 | 1979-03-23 | Evers Hans | Disinfecting and cleaning contact lenses without allergic reaction - with cold soln. contg. ene:diol redox system, water-soluble oxidising agent and opt. heavy metal salt catalyst |
EP0037078A2 (en) * | 1980-03-27 | 1981-10-07 | Green Cross Corporation | Process for heat treatment of aqueous solution containing human blood coagulation factor XIII |
WO1982003871A1 (en) * | 1981-04-27 | 1982-11-11 | Baxter Travenol Lab | Process for making novel blood clotting enzyme compositions |
DE3134050A1 (en) * | 1981-08-28 | 1983-03-10 | Dr. Franz Köhler Chemie GmbH, 6146 Alsbach | Solution for sterilising and removing pyrogens from stainless steel lines and filters in a closed system |
EP0139994A1 (en) * | 1983-08-25 | 1985-05-08 | Allergan, Inc. | Process and kit for disinfection of contact lenses |
Non-Patent Citations (2)
Title |
---|
BIOLOGICAL ABSTRACTS/RRM, Band 13, Zusammenfassung 1724; M. SPROESSIG et al.: "Serum sterilization in cold by per acetic-acid", & JOURNAL OF HYGIENE EPIDEMIOLOGY MICROBIOLOGY AND IMMUNOLOGY (PRAGUE) (CZECHOSLOVAKIA) 1976, Band 20, Nr. 2, Seiten 157-163 * |
THE JOURNAL OF IMMUNOLOGY, Band 124, Nr. 3, M{rz 1980, Seiten 1378-1382, The Williams & Wilkins Co., US; E.C. JONG et al.: "Bactericidal activity of eosinophil peroxidase" * |
Also Published As
Publication number | Publication date |
---|---|
ATA198383A (en) | 1986-06-15 |
AT382078B (en) | 1987-01-12 |
ES8506449A1 (en) | 1985-08-01 |
JPS606620A (en) | 1985-01-14 |
CA1211709A (en) | 1986-09-23 |
DK265084A (en) | 1984-12-01 |
DK265084D0 (en) | 1984-05-29 |
EP0127605A2 (en) | 1984-12-05 |
ES532863A0 (en) | 1985-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Designated state(s): AT BE CH DE FR GB IT LI NL SE |
|
PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH DE FR GB IT LI NL SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19870729 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: EIBL, JOHANN, DR. Inventor name: WOEBER, GUENTER, PROF. DR. |