EP0120341A3 - Process for the preparation of pentadienol derivatives - Google Patents

Process for the preparation of pentadienol derivatives Download PDF

Info

Publication number
EP0120341A3
EP0120341A3 EP84102224A EP84102224A EP0120341A3 EP 0120341 A3 EP0120341 A3 EP 0120341A3 EP 84102224 A EP84102224 A EP 84102224A EP 84102224 A EP84102224 A EP 84102224A EP 0120341 A3 EP0120341 A3 EP 0120341A3
Authority
EP
European Patent Office
Prior art keywords
pentadienol
derivatives
preparation
pentadienol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP84102224A
Other languages
German (de)
Other versions
EP0120341A2 (en
EP0120341B1 (en
Inventor
Teodor Lukac
Milan Dr. Soukup
Erich Dr. Widmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of EP0120341A2 publication Critical patent/EP0120341A2/en
Publication of EP0120341A3 publication Critical patent/EP0120341A3/en
Application granted granted Critical
Publication of EP0120341B1 publication Critical patent/EP0120341B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP84102224A 1983-03-25 1984-03-02 Process for the preparation of pentadienol derivatives Expired EP0120341B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1646/83 1983-03-25
CH164683 1983-03-25

Publications (3)

Publication Number Publication Date
EP0120341A2 EP0120341A2 (en) 1984-10-03
EP0120341A3 true EP0120341A3 (en) 1985-11-27
EP0120341B1 EP0120341B1 (en) 1989-01-25

Family

ID=4215324

Family Applications (1)

Application Number Title Priority Date Filing Date
EP84102224A Expired EP0120341B1 (en) 1983-03-25 1984-03-02 Process for the preparation of pentadienol derivatives

Country Status (4)

Country Link
US (1) US4701540A (en)
EP (1) EP0120341B1 (en)
JP (1) JPS59176224A (en)
DE (1) DE3476381D1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772755A (en) * 1987-03-19 1988-09-20 Mcneilab, Inc. 1,2-1,4 addition reaction sequence leading to disubstituted acelylenes
US5227507A (en) * 1987-03-27 1993-07-13 Hoffmann-La Roche Inc. Ethynylcyclohexene compounds and processes for manufacture thereof
DK171297B1 (en) * 1987-03-27 1996-08-26 Hoffmann La Roche Process for the preparation of cyclohexene derivatives as intermediates for the preparation of zeaxanthin and cyclohexene derivatives
US4798893A (en) * 1987-09-21 1989-01-17 Mcneilab, Inc. Process for producing 1-(5-substituted-2-ethynylphenyl)-2-propanones
US6090950A (en) * 1996-08-23 2000-07-18 Zeeland Chemicals, Inc. Chiral hydride complexes
DE19723480A1 (en) * 1997-06-04 1998-12-10 Basf Ag Process for the preparation of zeaxanthin, intermediates for this process and process for its preparation
DE10049271A1 (en) * 2000-09-28 2002-04-11 Basf Ag Production of cyclohexene derivatives with pentadienyl substituents, e.g astaxanthin compounds, comprises reduction of corresponding alken-ynyl derivatives with a mixture of zinc and ammonium or copper salt

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2032906A1 (en) * 1969-07-04 1971-01-07 F Hoffmann La Roche & Co AG, Basel (Schweiz) Selective hydrogenation of organic compds - using a metal hydride catalyst
DE2625259A1 (en) * 1975-06-09 1976-12-30 Hoffmann La Roche PROCESS FOR THE PRODUCTION OF CYCLIC OXO COMPOUNDS
EP0004621A2 (en) * 1978-03-27 1979-10-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the multi-step preparation of zeaxanthine and alloxanthine starting from derivatives of cyclohexanon and cyclohexanol; derivatives of cyclohexanon and cyclohexanol
FR2467837A1 (en) * 1979-10-24 1981-04-30 Firmenich & Cie NOVEL ACETYLENE COMPOUNDS, OBTAINING AND APPLICATION FOR THE PREPARATION OF ALICYCLIC KETONES, SUCH AS B-DAMASCENONE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2798101A (en) * 1957-07-02 L-hydroxy-j-methyl-s-
US2655548A (en) * 1953-10-13 Chx r r
US2671112A (en) * 1950-04-21 1954-03-02 Inhoffen Hans Herloff Process for the manufacture of beta-carotene
US2705728A (en) * 1951-05-21 1955-04-05 Hoffmann La Roche Process for the preparation of unsaturated alicyclic 2-methylbutanal compounds
CH623304A5 (en) * 1975-11-30 1981-05-29 Hoffmann La Roche

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2032906A1 (en) * 1969-07-04 1971-01-07 F Hoffmann La Roche & Co AG, Basel (Schweiz) Selective hydrogenation of organic compds - using a metal hydride catalyst
DE2625259A1 (en) * 1975-06-09 1976-12-30 Hoffmann La Roche PROCESS FOR THE PRODUCTION OF CYCLIC OXO COMPOUNDS
EP0004621A2 (en) * 1978-03-27 1979-10-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the multi-step preparation of zeaxanthine and alloxanthine starting from derivatives of cyclohexanon and cyclohexanol; derivatives of cyclohexanon and cyclohexanol
FR2467837A1 (en) * 1979-10-24 1981-04-30 Firmenich & Cie NOVEL ACETYLENE COMPOUNDS, OBTAINING AND APPLICATION FOR THE PREPARATION OF ALICYCLIC KETONES, SUCH AS B-DAMASCENONE

Also Published As

Publication number Publication date
EP0120341A2 (en) 1984-10-03
EP0120341B1 (en) 1989-01-25
US4701540A (en) 1987-10-20
DE3476381D1 (en) 1989-03-02
JPH0557974B2 (en) 1993-08-25
JPS59176224A (en) 1984-10-05

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