EP0086833A1 - Reagent storage and delivery system - Google Patents

Reagent storage and delivery system

Info

Publication number
EP0086833A1
EP0086833A1 EP19820902884 EP82902884A EP0086833A1 EP 0086833 A1 EP0086833 A1 EP 0086833A1 EP 19820902884 EP19820902884 EP 19820902884 EP 82902884 A EP82902884 A EP 82902884A EP 0086833 A1 EP0086833 A1 EP 0086833A1
Authority
EP
European Patent Office
Prior art keywords
container
hollow needle
interior
needle
supporting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19820902884
Other languages
German (de)
French (fr)
Inventor
Arthur Milton Harris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of EP0086833A1 publication Critical patent/EP0086833A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67D—DISPENSING, DELIVERING OR TRANSFERRING LIQUIDS, NOT OTHERWISE PROVIDED FOR
    • B67D3/00—Apparatus or devices for controlling flow of liquids under gravity from storage containers for dispensing purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers

Definitions

  • the invention relates to the field of contain- ing apparatus. More particularly, the invention relates to a container system which includes a means for dispens ⁇ ing a substance- from the containers.
  • the invention includes at least one container which is secured to a rack wherein, upon securing the container to the rack, a seal on the container is pierced to allow the liquid within the container to be drained therefrom.
  • the invention is an apparatus for supplying one or more substances "to an analytical instrument. It in ⁇ cludes at least one container defining an interior of predetermined volume with a neck portion having an open ⁇ ing through the container communicating with the in- terior. A sealing means is insertable into the mouth. A supporting means onto which the container is secured includes a means for piercing the sealing means when the container is secured to the supporting means.
  • the supporting means includes a rack having receptacles to engage and secure the containers by engag ⁇ ing with a neck portion on the containers.
  • the recepta ⁇ cles include a hollow needle to pierce the septum which seals the opening in the neck portion of the container.
  • the hollow needle extends through the septum such that an inlet in the needle allows the reagent or other substance in the container to flow from the container through the needle and into an analytical instrument.
  • FIG. 1 is a partially sectioned view of the containers and the supporting rack
  • Fig. 2 is a sectional view of the container secured to the rack;
  • Fig. 3 is a view of the containers in a separ- ate storage rack; and Fig. 4 shows a container with a collapsible liner therein.
  • a plurality of containers 11, 12, and 13 each have a neck portion 14 defining a mouth 15 into which a septum 16 is inserted.
  • Neck por ⁇ tions 14 include threads 17 on the outside thereof.
  • Containers 11, 12, and 13 also include a frangible vent- tab 18.
  • Containers 11, 12, and 13 each define an in- terior of predetermined volume.
  • a supporting rack 19 includes container caps 21, 22, and 23, respectively, sized to fit containers 11, 12, and 13. Caps 21, 22, and 23 are attached to supporting rack 19.
  • Caps 21, 22, and 23 include threaded portions on the interior of the caps • for engagement with threaded neck portions 14 on contain ⁇ ers 11, 12, and 13.
  • Caps 21, 22, and 23 also include a hollow needle 24 preferably at the center of each cap.
  • a conduit 25 is connected to hollow needle 24.
  • FIG. 2 the attachment of a con- tainer to supporting rack 19 is shown.
  • this attachment will be described with ref ⁇ erence to container 11 , but it should be expressly under ⁇ stood that containers 12 and 13 are attached in a like manner.
  • Neck portion 14 of container 11 is threadably engaged with cap 21 , itself attached to supporting rack 19.
  • Septum 16 seals a liquid or other substance within the interior of container 11.
  • Hollow needle 24 pene ⁇ trates septum 16 and extends into the interior of con ⁇ tainer 11 such that an inlet 26 in hollow needle 24 com- unicates with the predetermined volume in container 11 allowing the liquid to flow therethrough.
  • Conduit 25 is attached to hollow needle 24.
  • containers 11, 12, and 13 may be placed in a separate storage rack 27 to allow storage of the reagents apart from the analytical instru ⁇ ment.
  • Containers 11, 12, and 13 include holes 28 left by the removal of the frangible vent tab 18 (Fig. 1).
  • a container 29 including a collapsible liner 31 in the interior prede ⁇ termined volume of container 29.
  • the threaded neck portion 14 may be attached to a supporting rack 19.
  • Septum 16 is configured as described above.
  • containers 11, 12, and 13 define predetermined volumes into which a reagent or other substance is placed.
  • Septum 16 fitting in mouth 15 of neck portions 14, provides a liquid and air ⁇ tight seal such that the reagent or other substance en ⁇ closed in containers 11, 12, and 13 is prevented from escaping.
  • Septums 16 are made of an elastomeric material such as silicone rubber such that, when containers 11, 12, and 13 are screwed into caps 21, 22, and 23, respec ⁇ tively, needles 24 pierce septum 16 and extend into the interior defined by the containers. This is more clearly shown in Fig. 2 where container 11 is shown in place as screwed into cap 21.
  • Reagent is conducted from container 11 to a reaction site (not shown) through hollow needle 24 and conduit 25.
  • frangible valve 18 is opened, such as by breaking the tab, so as to permit uniform flow of reagent.
  • the containers shown in Fig. 1 may be removed from rack 19 without leakage of the contents of contain- ers 11, 12 or 13. That is, if, for example, at the end of a day all the reagents are not used from containers 11, 12, or 13, then the containers may be removed to be stored in a refrigerated environment or other suitable location. Upon unscrewing containers 11, 12, and 13, needle 24 will be pulled back through septum 16. Because of the elastomeric nature of septum 16, however, the elastomeric material will fill the space formally occu ⁇ file by the needle and thus the hole punched by the nee- die 24 will be effectively sealed.
  • the container illustrated in Figs. 1 and 2 once the frangible vent is opened a hole is formed in the container bottom.
  • the container may be placed in a suitable holding means for storage such as storage rack 27 to keep the bottles turned neck down as shown in Fig. 3.
  • This rack may then be placed into the desired storage loca ⁇ tion.
  • This rack is similar to rack 19 except that no needles are included to penetrate septum 16.
  • a collapsible liner 31 can be used in a container 29, eliminating the need for venting container 29. That is, as reagent is drawn from collapsible liner 31, no air is needed to equalize the pressure inside the liner and thus venting is un ⁇ necessary.
  • Container 29 is otherwise identical to con ⁇ tainers 11, 12 and 13 including septum 16 and threaded neck portion 14, the structure and function of which have been described in connection with Figs. 1 and 2.
  • the invention provides a safe contamination-free package for reagents to ensure
  • the removability of the con ⁇ tainers from the rack allows them to be placed into a storage rack if all the reagent is not used. Different size threads may be used on each container and corres ⁇ ponding cap. In this way correct placement of each con ⁇ tainer on the supporting rack may be assured. Alterna ⁇ tively, color coding could be used.
  • the resealable sep ⁇ tum prevents leakage when the containers are removed from the supporting rack.
  • the collapsible liner may also be made opaque such that- light-sensitive reagents may be protected.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'appareil de l'invention pour le stockage et la distribution d'un agent de réaction comprend des conteneurs (11, 12, 13) pourvus de septa élastomères (16) dans leurs embouchures (15). Lorsqu'ils sont fixés à un ratelier de support (19), une aiguille creuse (24) sur le ratelier de support (19) perce les septas élastomères (15) et permet la distribution de l'agent de réaction qui s'écoule des conteneurs (11, 12, 13) au travers de l'aiguille (24).The apparatus of the invention for the storage and distribution of a reaction agent comprises containers (11, 12, 13) provided with septa elastomers (16) in their mouths (15). When attached to a support rack (19), a hollow needle (24) on the support rack (19) pierces the elastomeric septas (15) and allows the distribution of the reaction agent which flows from the containers (11, 12, 13) through the needle (24).

Description

REAGENT STORAGE AND DELIVERY SYSTEM
Background of the Invention Field of the Invention
The invention relates to the field of contain- ing apparatus. More particularly, the invention relates to a container system which includes a means for dispens¬ ing a substance- from the containers. By way of further characterization, but not by way of limitation thereto, the invention includes at least one container which is secured to a rack wherein, upon securing the container to the rack, a seal on the container is pierced to allow the liquid within the container to be drained therefrom.
Description of the Prior Art
In analytical instruments, such as medical instrumentation, samples of body fluids are combined with reagents or other substances and tested for specific components and percentages thereof. It is important, when utilizing these reagents or substances, that the reagents be kept sterile and free from contamination. In addition, the substances must be stored when not in use. Many instruments employ refillable reservoirs into which the new reagent is added. Many other instruments employ reagent bottles into which tubing may be inserted and pumps are used to pump out the liquids or other sub- stances to be used. While these arrangements are suited for their intended purpose, it would be desirable to have a containment system wherein the bottles of reagents may be inserted onto or removed from the instrument easily, with no or minimal leakage, and stored safely.
Long-term storage of the reagents is done in a refrigerated atmosphere and thus the storage system used for the reagents must allow for easy and rapid insertion onto and removal from the instrument. In addition, the reagents must be kept substantially sealed within the container to prevent leakage and contamination.
Summary of the Invention The invention is an apparatus for supplying one or more substances "to an analytical instrument. It in¬ cludes at least one container defining an interior of predetermined volume with a neck portion having an open¬ ing through the container communicating with the in- terior. A sealing means is insertable into the mouth. A supporting means onto which the container is secured includes a means for piercing the sealing means when the container is secured to the supporting means.
The supporting means includes a rack having receptacles to engage and secure the containers by engag¬ ing with a neck portion on the containers. The recepta¬ cles include a hollow needle to pierce the septum which seals the opening in the neck portion of the container. When the containers are secured to the supporting rack, the hollow needle extends through the septum such that an inlet in the needle allows the reagent or other substance in the container to flow from the container through the needle and into an analytical instrument.
Brief Description of the Drawings Fig. 1 is a partially sectioned view of the containers and the supporting rack;
Fig. 2 is a sectional view of the container secured to the rack;
Fig. 3 is a view of the containers in a separ- ate storage rack; and Fig. 4 shows a container with a collapsible liner therein.
Description of the Preferred Embodiment Referring to Fig. 1, a plurality of containers 11, 12, and 13 each have a neck portion 14 defining a mouth 15 into which a septum 16 is inserted. Neck por¬ tions 14 include threads 17 on the outside thereof. Containers 11, 12, and 13 also include a frangible vent- tab 18. Containers 11, 12, and 13 each define an in- terior of predetermined volume. A supporting rack 19 includes container caps 21, 22, and 23, respectively, sized to fit containers 11, 12, and 13. Caps 21, 22, and 23 are attached to supporting rack 19. Caps 21, 22, and 23 include threaded portions on the interior of the caps • for engagement with threaded neck portions 14 on contain¬ ers 11, 12, and 13. Caps 21, 22, and 23 also include a hollow needle 24 preferably at the center of each cap. A conduit 25 is connected to hollow needle 24.
Referring to Fig. 2 , the attachment of a con- tainer to supporting rack 19 is shown. For purposes of illustration, this attachment will be described with ref¬ erence to container 11 , but it should be expressly under¬ stood that containers 12 and 13 are attached in a like manner. Neck portion 14 of container 11 is threadably engaged with cap 21 , itself attached to supporting rack 19. Septum 16 seals a liquid or other substance within the interior of container 11. Hollow needle 24 pene¬ trates septum 16 and extends into the interior of con¬ tainer 11 such that an inlet 26 in hollow needle 24 com- unicates with the predetermined volume in container 11 allowing the liquid to flow therethrough. Conduit 25 is attached to hollow needle 24. Referring to Fig. 3, containers 11, 12, and 13 may be placed in a separate storage rack 27 to allow storage of the reagents apart from the analytical instru¬ ment. Containers 11, 12, and 13 include holes 28 left by the removal of the frangible vent tab 18 (Fig. 1).
Referring to Fig. 4, a container 29 is shown including a collapsible liner 31 in the interior prede¬ termined volume of container 29. In this alternate em¬ bodiment, as with the previously described containers 11, 12, and 13, the threaded neck portion 14 may be attached to a supporting rack 19. Septum 16 is configured as described above.
Mode of Operation
Referring to Figs. 1 and 2, containers 11, 12, and 13 define predetermined volumes into which a reagent or other substance is placed. Septum 16, fitting in mouth 15 of neck portions 14, provides a liquid and air¬ tight seal such that the reagent or other substance en¬ closed in containers 11, 12, and 13 is prevented from escaping. Septums 16 are made of an elastomeric material such as silicone rubber such that, when containers 11, 12, and 13 are screwed into caps 21, 22, and 23, respec¬ tively, needles 24 pierce septum 16 and extend into the interior defined by the containers. This is more clearly shown in Fig. 2 where container 11 is shown in place as screwed into cap 21. Reagent is conducted from container 11 to a reaction site (not shown) through hollow needle 24 and conduit 25. To equalize the pressure between the exterior and interior of container 11, frangible valve 18 is opened, such as by breaking the tab, so as to permit uniform flow of reagent.
The containers shown in Fig. 1 may be removed from rack 19 without leakage of the contents of contain- ers 11, 12 or 13. That is, if, for example, at the end of a day all the reagents are not used from containers 11, 12, or 13, then the containers may be removed to be stored in a refrigerated environment or other suitable location. Upon unscrewing containers 11, 12, and 13, needle 24 will be pulled back through septum 16. Because of the elastomeric nature of septum 16, however, the elastomeric material will fill the space formally occu¬ pied by the needle and thus the hole punched by the nee- die 24 will be effectively sealed.
In the container illustrated in Figs. 1 and 2, once the frangible vent is opened a hole is formed in the container bottom. Thus, if the contents of the container is not completely used and the container is to be stored for reuse, the container may be placed in a suitable holding means for storage such as storage rack 27 to keep the bottles turned neck down as shown in Fig. 3. This rack may then be placed into the desired storage loca¬ tion. This rack is similar to rack 19 except that no needles are included to penetrate septum 16.
Alternatively to the frangible vent tab 18 shown in Fig. 1 , as shown in. Fig. 4 a collapsible liner 31 can be used in a container 29, eliminating the need for venting container 29. That is, as reagent is drawn from collapsible liner 31, no air is needed to equalize the pressure inside the liner and thus venting is un¬ necessary. Container 29 is otherwise identical to con¬ tainers 11, 12 and 13 including septum 16 and threaded neck portion 14, the structure and function of which have been described in connection with Figs. 1 and 2.
In addition to the convenience of disposable bottles and ease of handling, the invention provides a safe contamination-free package for reagents to ensure
__O PI reproducible results when employed with an analytical • instrument. In addition, the removability of the con¬ tainers from the rack allows them to be placed into a storage rack if all the reagent is not used. Different size threads may be used on each container and corres¬ ponding cap. In this way correct placement of each con¬ tainer on the supporting rack may be assured. Alterna¬ tively, color coding could be used. The resealable sep¬ tum prevents leakage when the containers are removed from the supporting rack. The collapsible liner may also be made opaque such that- light-sensitive reagents may be protected.
While a silicone rubber septum has been dis¬ closed, it should be understood that any elastomeric material would be suitable for use as a septum. Addi¬ tionally, while threads have been used to secure the containers to the rack, it should be understood that any type of fastening means such as clamps, snap fit, or press fit may be used. In addition, while a hollow needle has been disclosed as a means for piercing the septum, it should be expressly understood that any type of piercing means may be employed such as a knife, etc. Additionally, the hole in the hollow needle, while pref¬ erably placed on the side, may be advantageously placed in various positions on the needle in order to facilitate flow of the reagent from the container. Also, while frangible vent tabs have been disclosed to vent the con¬ tainers, it should be understood that any type of vent may be employed such as removable plugs, a double needle, .etc.
While particular forms of the invention have been disclosed with respect to a preferred embodiment thereof, it is not to be so limited as changes and modi¬ fications may be made without departing from the full intended scope of the invention.

Claims

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:
1. Apparatus supplying one or more substances to an analytical instrument comprising: at least one container, each said container defining an interior of predetermined volume and including an opening communi¬ cating with said interior; means, cooperative with each said container, for supporting each said container; means, insertible into said opening, for sub¬ stantially sealing said interior; means, cooperative with each said container and said supporting means, for securing each said container to said supporting means; and means, connected to said supporting means and communicable with said interior, for con¬ ducting said substances from said contain- . er.
2. Apparatus according to claim 1 wherein said support¬ ing means includes: a supporting rack; and at least one cap connected to said rack, said cap adapted to receive said at least one container.
3. Apparatus according to claim 1 wherein said sealing means includes an elastomeric septum.
4. Apparatus according to claim 1 wherein said securing means includes mating threaded portions on said container and said supporting means.
own
5. Apparatus according to claim 1 wherein said conduct¬ ing means includes a needle connected to said sup¬ porting means, said needle oriented to pierce said sealing means when said container is secured to said supporting means.
6. Apparatus according to claim 5 wherein said needle includes: an at least partially hollow needle communicat¬ ing with said predetermined volume, one end of said hollow needle configured to penetrate said sealing means and the other end of said hollow needle connectible to an analytical instrument; and said hollow needle including at least one inlet communicating with said predetermined volume.
7. Apparatus according to claim 6 wherein said at least one inlet is on a side wall of said hollow needle.
8. Apparatus according to claim 1 wherein said contain- er includes a concave bottom portion opposite to said opening, said concave bottom including a frang¬ ible vent thereon.
9. Apparatus according to claim 1 wherein said contain¬ er includes a deformable, flexible, liner within said predetermined volume.
10. A liquid storage and delivery system comprising: a supporting rack; at least one container defining an interior of predetermined volume, each such container including a neck portion having an open-
■ υRE ing, said neck portion including an en- gageable area matable with an engageable area on said supporting rack; an elastomeric septum insertible into the open- ing of each said container; and at least one needle, adjacent said engageable area on said rack and communicating with said interior.
11. Apparatus according to claim 10 wherein said needle includes: an at least partially hollow needle communicat¬ ing with said interior, one end of said hollow needle configured to penetrate said elastomeric septum and the other end of said hollow needle connectible to an ana¬ lytical instrument; and said hollow needle including at least one inlet for communication with said interior.
12. Apparatus according to claim 11 wherein said at least one inlet is on a side wall of said hollow needle.
13. Apparatus according to claim 10 wherein said con¬ tainer includes a concave bottom portion opposite to said open mouth portion, said concave bottom portion including a frangible vent thereon.
14. Apparatus according to claim 10 wherein said con¬ tainer includes a deformable, flexible liner within said predetermined volume.
15. Apparatus according to claim 10 wherein said engage- ' able area includes mating threads on said neck por¬ tion and said supporting rack.
EP19820902884 1981-08-31 1982-08-31 Reagent storage and delivery system Withdrawn EP0086833A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29765081A 1981-08-31 1981-08-31
US297650 1981-08-31

Publications (1)

Publication Number Publication Date
EP0086833A1 true EP0086833A1 (en) 1983-08-31

Family

ID=23147195

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19820902884 Withdrawn EP0086833A1 (en) 1981-08-31 1982-08-31 Reagent storage and delivery system

Country Status (3)

Country Link
EP (1) EP0086833A1 (en)
JP (1) JPS58501367A (en)
WO (1) WO1983000932A1 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8826627D0 (en) * 1988-11-14 1988-12-21 Diversey Corp Dispenser
DE3938559A1 (en) * 1989-11-21 1991-05-23 Boehringer Mannheim Gmbh REAGENT STORAGE SYSTEM FOR A MEDICAL ANALYZER
US5253774A (en) * 1992-06-26 1993-10-19 Bio-Rad Laboratories, Inc. Reagent receptacle and support rack for automated clinical analyzers
US6145968A (en) * 1997-03-07 2000-11-14 Encad, Inc. System and method for supplying ink to a printer
US6079823A (en) * 1997-07-23 2000-06-27 Marconi Data Systems Inc. Ink bottle with puncturable diaphragm closure
JP3582316B2 (en) 1997-08-20 2004-10-27 株式会社日立製作所 Chemical analyzer
US6193933B1 (en) * 1997-10-27 2001-02-27 Hitachi, Ltd. Automatic analysis apparatus
US6095370A (en) * 1997-12-18 2000-08-01 Americlean Systems, Inc. Encapsulated liquid dispensing device and method
US6109480A (en) * 1998-07-27 2000-08-29 Ecolab Inc. Liquid dispenser and docking station for mating container
US6152327A (en) * 1998-11-12 2000-11-28 Americlean Systems, Inc. Dispensing method and device
EP1078880B1 (en) 1999-08-05 2003-03-19 The Procter & Gamble Company Dispensing device comprising a reservoir and attachment means provided with protected piercing means
US6386392B1 (en) 1999-11-02 2002-05-14 The Procter & Gamble Company Reservoirs for use with cleaning devices
US6321941B1 (en) 2000-04-20 2001-11-27 The Procter & Gamble Company Consumer safe fitment for connecting a reservoir to a dispensing appliance
US6164768A (en) * 1999-11-09 2000-12-26 Illinois Tool Works Inc. Adapter and mating bottle cap for coupling bottles to ink supplies
US6390614B2 (en) * 2000-01-06 2002-05-21 Hewlett-Packard Company Fluid-jet print cartridge and method
US8153061B2 (en) 2005-11-23 2012-04-10 Siemens Healthcare Diagnostics Inc. Storage and supply system for clinical solutions used in an automatic analyzer
DE102009013534A1 (en) * 2009-03-19 2010-09-23 Crinotec Gmbh Method and device for determining an impurity content in a matrix
DE102009052029A1 (en) * 2009-11-05 2011-05-26 Meiko Maschinenbau Gmbh & Co. Kg Suction lance and container with coding geometry
EP2736644B1 (en) 2011-07-29 2020-12-02 Corning Incorporated Magnetic separation device and methods
DE102012208074A1 (en) * 2012-05-15 2013-11-21 Robert Bosch Gmbh Device for sample introduction into a microfluidic system
DE102012216881A1 (en) * 2012-09-20 2014-03-20 Kba-Metronic Gmbh print Setup
USD713931S1 (en) 2013-01-09 2014-09-23 Central Garden & Pet Company Sprayer
CN105121294B (en) 2013-03-13 2018-09-04 雅培实验室 Keying lid for container and relative device and system
CN105474019A (en) * 2013-07-26 2016-04-06 积水医疗株式会社 Reagent supplying device
DE102013218952A1 (en) 2013-09-20 2015-03-26 Kba-Metronic Gmbh print Setup
USD886609S1 (en) 2013-12-20 2020-06-09 Abbott Laboratories Bottle cap
USD869276S1 (en) 2013-12-20 2019-12-10 Abbott Laboratories Bottle cap
USD881709S1 (en) 2013-12-20 2020-04-21 Abbott Laboratories Bottle with cap
CN111495447B (en) 2015-05-01 2022-08-26 雅培制药有限公司 Device for removing liquid contents of a container
CN105944776A (en) * 2016-07-13 2016-09-21 贵州大学 {0><}0{>Simple polyacrylamide gel pouring device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2438024A (en) * 1946-01-26 1948-03-16 Stransky Joseph Milk bottle utility device
US2628130A (en) * 1949-01-15 1953-02-10 Knapp Monarch Co Spraying device
US2911123A (en) * 1956-07-23 1959-11-03 Saccomanno Geno Bottle cap
US3186599A (en) * 1963-10-15 1965-06-01 Evelyn S Levinson Dispenser for liquid in upright container with controlled atmosphere
GB1564009A (en) * 1975-08-28 1980-04-02 Svensson J A Apparatus for collecting fluid samples in containers sealed by a resilient stopper
US4098431A (en) * 1977-01-13 1978-07-04 Cine Magnetics Inc. Chemical replenishing system
US4234103A (en) * 1978-03-31 1980-11-18 Baxter Travenol Laboratories, Inc. Diagnostic reagent dispensing bottle
US4236647A (en) * 1979-01-15 1980-12-02 Kotturan Paulson A Container for sterile liquids
US4306667A (en) * 1979-10-12 1981-12-22 The Coca-Cola Company Post-mix beverage dispensing system syrup package, valving system, and carbonator therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO8300932A1 *

Also Published As

Publication number Publication date
WO1983000932A1 (en) 1983-03-17
JPS58501367A (en) 1983-08-18

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