EP0077759A3 - Phenyl urea - Google Patents
Phenyl urea Download PDFInfo
- Publication number
- EP0077759A3 EP0077759A3 EP82810428A EP82810428A EP0077759A3 EP 0077759 A3 EP0077759 A3 EP 0077759A3 EP 82810428 A EP82810428 A EP 82810428A EP 82810428 A EP82810428 A EP 82810428A EP 0077759 A3 EP0077759 A3 EP 0077759A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- phenyl urea
- urea
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C07D213/643—2-Phenoxypyridines; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT82810428T ATE31298T1 (en) | 1981-10-20 | 1982-10-14 | PHENYLUREAS. |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH6691/81 | 1981-10-20 | ||
CH669181 | 1981-10-20 | ||
CH3231/82 | 1982-05-26 | ||
CH323182 | 1982-05-26 | ||
CH524882 | 1982-09-03 | ||
CH5248/82 | 1982-09-03 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0077759A2 EP0077759A2 (en) | 1983-04-27 |
EP0077759A3 true EP0077759A3 (en) | 1984-03-07 |
EP0077759B1 EP0077759B1 (en) | 1987-12-09 |
Family
ID=27174204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP82810428A Expired EP0077759B1 (en) | 1981-10-20 | 1982-10-14 | Phenyl urea |
Country Status (10)
Country | Link |
---|---|
US (1) | US4511571A (en) |
EP (1) | EP0077759B1 (en) |
AU (2) | AU555936B2 (en) |
BR (1) | BR8206089A (en) |
CA (1) | CA1244442A (en) |
DE (1) | DE3277810D1 (en) |
ES (1) | ES8402575A1 (en) |
IL (1) | IL67079A0 (en) |
NZ (1) | NZ202225A (en) |
TR (1) | TR21387A (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0079311B1 (en) * | 1981-11-10 | 1987-03-18 | Ciba-Geigy Ag | Phenylbenzoyl ureas as pesticides |
EP0167491A3 (en) * | 1984-07-06 | 1986-12-30 | Ciba-Geigy Ag | Thiobarbituric-acid derivatives |
EP0177455A3 (en) * | 1984-10-05 | 1987-07-15 | Ciba-Geigy Ag | N-benzoylphenyl urea |
EP0185621B1 (en) * | 1984-12-20 | 1991-10-16 | Ciba-Geigy Ag | Benzoylphenyl urea |
US5135953A (en) * | 1984-12-28 | 1992-08-04 | Ciba-Geigy | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals |
DE3545570A1 (en) * | 1985-12-21 | 1987-06-25 | Hoechst Ag | NEW PYRIDINE DERIVATIVES AND THEIR N-OXIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS INTERMEDIATE PRODUCTS |
DE3626503A1 (en) * | 1986-08-05 | 1988-02-11 | Celamerck Gmbh & Co Kg | METHOD FOR PRODUCING BENZOYL UREA |
US4983605A (en) * | 1986-10-23 | 1991-01-08 | Ishihara Sangyo Kaisha Ltd. | Pharmaceutical composition |
EP0320448B1 (en) * | 1987-12-07 | 1994-12-28 | Ciba-Geigy Ag | 3-Aminobenzoyl phenyl urea |
US6344476B1 (en) * | 1997-05-23 | 2002-02-05 | Bayer Corporation | Inhibition of p38 kinase activity by aryl ureas |
US7517880B2 (en) * | 1997-12-22 | 2009-04-14 | Bayer Pharmaceuticals Corporation | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas |
US7329670B1 (en) * | 1997-12-22 | 2008-02-12 | Bayer Pharmaceuticals Corporation | Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas |
US20080300281A1 (en) * | 1997-12-22 | 2008-12-04 | Jacques Dumas | Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas |
US20080269265A1 (en) * | 1998-12-22 | 2008-10-30 | Scott Miller | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas |
US8124630B2 (en) * | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
RU2319693C9 (en) * | 1999-01-13 | 2008-08-20 | Байер Копэрейшн | Derivatives of urea (variants), pharmaceutical composition (variants) and method for treatment of diseases associated with cancer cells growth (variants) |
US7928239B2 (en) | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
EP1140840B1 (en) | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
WO2000041698A1 (en) * | 1999-01-13 | 2000-07-20 | Bayer Corporation | φ-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS |
US7235576B1 (en) | 2001-01-12 | 2007-06-26 | Bayer Pharmaceuticals Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
MEP36208A (en) * | 2001-12-03 | 2011-02-10 | Bayer Corp | Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers |
US20080108672A1 (en) * | 2002-01-11 | 2008-05-08 | Bernd Riedl | Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors |
AU2003210969A1 (en) * | 2002-02-11 | 2003-09-04 | Bayer Corporation | Aryl ureas with raf kinase and angiogenesis inhibiting activity |
ES2378670T3 (en) | 2002-02-11 | 2012-04-16 | Bayer Healthcare, Llc | Aril ureas as kinase inhibitors |
EP1478358B1 (en) | 2002-02-11 | 2013-07-03 | Bayer HealthCare LLC | Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis |
US20030216396A1 (en) * | 2002-02-11 | 2003-11-20 | Bayer Corporation | Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors |
UY28213A1 (en) | 2003-02-28 | 2004-09-30 | Bayer Pharmaceuticals Corp | NEW CYANOPIRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS. |
EP1626714B1 (en) * | 2003-05-20 | 2007-07-04 | Bayer Pharmaceuticals Corporation | Diaryl ureas for diseases mediated by pdgfr |
SI1663978T1 (en) * | 2003-07-23 | 2008-02-29 | Bayer Pharmaceuticals Corp | Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4003733A (en) * | 1974-01-22 | 1977-01-18 | The Dow Chemical Company | Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives |
DE2748636A1 (en) * | 1976-10-29 | 1978-05-03 | Ishihara Mining & Chemical Co | N-BENZOYL-N'-PYRIDYLOXY-PHENYLURA AND METHOD FOR PREPARING THE SAME |
EP0028870A1 (en) * | 1977-08-12 | 1981-05-20 | Imperial Chemical Industries Plc | Phenoxypyridine compound |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2450955C2 (en) * | 1974-10-26 | 1976-09-29 | Ofenbaugesellschaft Berg & Co | Method and device for patenting steel wire coiled into coils |
US4173637A (en) * | 1976-10-29 | 1979-11-06 | Ishihara Sangyo Kaisha Ltd. | N-Benzoyl-N'-pyridyloxy phenyl urea and insecticidal compositions thereof |
EP0185621B1 (en) * | 1984-12-20 | 1991-10-16 | Ciba-Geigy Ag | Benzoylphenyl urea |
-
1982
- 1982-10-12 US US06/433,763 patent/US4511571A/en not_active Expired - Lifetime
- 1982-10-14 DE DE8282810428T patent/DE3277810D1/en not_active Expired
- 1982-10-14 EP EP82810428A patent/EP0077759B1/en not_active Expired
- 1982-10-18 CA CA000413667A patent/CA1244442A/en not_active Expired
- 1982-10-18 TR TR21387A patent/TR21387A/en unknown
- 1982-10-19 AU AU89602/82A patent/AU555936B2/en not_active Ceased
- 1982-10-19 BR BR8206089A patent/BR8206089A/en unknown
- 1982-10-19 ES ES516648A patent/ES8402575A1/en not_active Expired
- 1982-10-19 NZ NZ202225A patent/NZ202225A/en unknown
- 1982-10-26 IL IL67079A patent/IL67079A0/en unknown
-
1986
- 1986-08-26 AU AU61848/86A patent/AU596370B2/en not_active Ceased
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4003733A (en) * | 1974-01-22 | 1977-01-18 | The Dow Chemical Company | Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives |
DE2748636A1 (en) * | 1976-10-29 | 1978-05-03 | Ishihara Mining & Chemical Co | N-BENZOYL-N'-PYRIDYLOXY-PHENYLURA AND METHOD FOR PREPARING THE SAME |
EP0028870A1 (en) * | 1977-08-12 | 1981-05-20 | Imperial Chemical Industries Plc | Phenoxypyridine compound |
Also Published As
Publication number | Publication date |
---|---|
AU596370B2 (en) | 1990-05-03 |
AU6184886A (en) | 1987-04-09 |
CA1244442A (en) | 1988-11-08 |
US4511571A (en) | 1985-04-16 |
ES516648A0 (en) | 1984-03-01 |
EP0077759B1 (en) | 1987-12-09 |
AU555936B2 (en) | 1986-10-16 |
DE3277810D1 (en) | 1988-01-21 |
TR21387A (en) | 1984-05-10 |
EP0077759A2 (en) | 1983-04-27 |
ES8402575A1 (en) | 1984-03-01 |
AU8960282A (en) | 1983-04-28 |
NZ202225A (en) | 1985-11-08 |
IL67079A0 (en) | 1983-02-23 |
BR8206089A (en) | 1983-09-13 |
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Legal Events
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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