EP0000392A3 - Cephalosporins and penicillins, processes for their preparation and pharmaceutical compositions containing them - Google Patents

Cephalosporins and penicillins, processes for their preparation and pharmaceutical compositions containing them Download PDF

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Publication number
EP0000392A3
EP0000392A3 EP78100352A EP78100352A EP0000392A3 EP 0000392 A3 EP0000392 A3 EP 0000392A3 EP 78100352 A EP78100352 A EP 78100352A EP 78100352 A EP78100352 A EP 78100352A EP 0000392 A3 EP0000392 A3 EP 0000392A3
Authority
EP
European Patent Office
Prior art keywords
penicillins
cephalosporins
processes
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP78100352A
Other versions
EP0000392B1 (en
EP0000392A2 (en
Inventor
Michael Dr Preiss
Hans-Bodo Dr. Konig
Karl Georg Dr. Metzger
Peter Dr. Feyen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of EP0000392A2 publication Critical patent/EP0000392A2/en
Publication of EP0000392A3 publication Critical patent/EP0000392A3/en
Application granted granted Critical
Publication of EP0000392B1 publication Critical patent/EP0000392B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
EP78100352A 1977-07-16 1978-07-11 Cephalosporins and penicillins, processes for their preparation and pharmaceutical compositions containing them Expired EP0000392B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772732283 DE2732283A1 (en) 1977-07-16 1977-07-16 BETA-LACTAM COMPOUNDS
DE2732283 1977-07-16

Publications (3)

Publication Number Publication Date
EP0000392A2 EP0000392A2 (en) 1979-01-24
EP0000392A3 true EP0000392A3 (en) 1979-08-22
EP0000392B1 EP0000392B1 (en) 1982-04-28

Family

ID=6014140

Family Applications (1)

Application Number Title Priority Date Filing Date
EP78100352A Expired EP0000392B1 (en) 1977-07-16 1978-07-11 Cephalosporins and penicillins, processes for their preparation and pharmaceutical compositions containing them

Country Status (11)

Country Link
US (2) US4215118A (en)
EP (1) EP0000392B1 (en)
JP (1) JPS5439091A (en)
AT (1) AT365193B (en)
AU (1) AU525027B2 (en)
CA (1) CA1122593A (en)
DE (2) DE2732283A1 (en)
DK (1) DK318278A (en)
ES (1) ES471770A1 (en)
IL (1) IL55130A (en)
IT (1) IT1097816B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA813610B (en) * 1980-06-06 1982-06-30 Beecham Group Plc Penicillin derivatives,processes for their preparation and compositions containing them
NZ197416A (en) * 1980-06-26 1983-11-18 Beecham Group Ltd Penicillin derivatives and pharmaceutical compositions
US4436904A (en) * 1981-02-14 1984-03-13 Kanto Ishi Pharmaceutical Co., Ltd. Cephalosporins
EP0066406A1 (en) * 1981-05-28 1982-12-08 Beecham Group Plc Beta-lactam antibiotics
DE3215085A1 (en) * 1982-04-22 1983-10-27 Bayer Ag, 5090 Leverkusen SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
DE3431273A1 (en) * 1984-08-25 1986-03-06 Bayer Ag, 5090 Leverkusen CRYSTALLINE SODIUM SALT OF THE D-6 - ((ALPHA) - (2-OXO-3-FURFURYL-IDEN-AMINO-IMIDAZOLIDIN-1-YL) -CARBONYLAMINO) -THIENYL-2-ACETAMIDO) -PENICILLANIC ACID, METHODS OF PROCESSING IN MEDICINAL PRODUCTS
GB8519264D0 (en) * 1985-07-31 1985-09-04 Baldwin J E Chemical compounds
GB8713061D0 (en) * 1987-06-04 1987-07-08 Beecham Group Plc Compounds
AU782938B2 (en) * 2001-08-28 2005-09-08 Boss Rubber Technologies Pty Ltd Resilient product

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2292471A1 (en) * 1974-11-28 1976-06-25 Bayer Ag NEW ANTIBIOTICS OF THE B-LACTAM TYPE, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM
FR2359145A1 (en) * 1976-07-23 1978-02-17 Bayer Ag NEW ANTIBIOTICS OF THE B-LACTAM TYPE, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687949A (en) * 1969-01-21 1972-08-29 Bristol Myers Co Synthetic cephalosporins
US3959258A (en) * 1970-05-25 1976-05-25 Bayer Aktiengesellschaft Ureidoacetamido-penicillins
US3974142A (en) * 1971-10-23 1976-08-10 Bayer Aktiengesellschaft Penicillins
US4086340A (en) * 1974-02-18 1978-04-25 Bayer Aktiengesellschaft Cephalosporins and their production
US4087424A (en) * 1974-05-09 1978-05-02 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
JPS5852996B2 (en) * 1975-03-25 1983-11-26 バイエル・アクチエンゲゼルシヤフト Beta-lactams and antibacterial agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2292471A1 (en) * 1974-11-28 1976-06-25 Bayer Ag NEW ANTIBIOTICS OF THE B-LACTAM TYPE, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM
FR2359145A1 (en) * 1976-07-23 1978-02-17 Bayer Ag NEW ANTIBIOTICS OF THE B-LACTAM TYPE, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCT CONTAINING THEM

Also Published As

Publication number Publication date
AU3801878A (en) 1980-01-17
JPS5439091A (en) 1979-03-24
AT365193B (en) 1981-12-28
EP0000392B1 (en) 1982-04-28
IL55130A0 (en) 1978-09-29
DE2861766D1 (en) 1982-06-09
US4338434A (en) 1982-07-06
IL55130A (en) 1982-01-31
ATA510878A (en) 1981-05-15
DE2732283A1 (en) 1979-01-25
EP0000392A2 (en) 1979-01-24
IT1097816B (en) 1985-08-31
AU525027B2 (en) 1982-10-14
IT7825714A0 (en) 1978-07-14
US4215118A (en) 1980-07-29
ES471770A1 (en) 1979-02-01
DK318278A (en) 1979-01-17
CA1122593A (en) 1982-04-27

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